Results 41 to 50 of about 3,419 (134)
Engineering Caffeic Acid O‐Methyltransferase for Efficient De Novo Ferulic Acid Synthesis
Engineering in Life Sciences, Volume 25, Issue 4, April 2025.ABSTRACT Ferulic acid is a high‐value chemical synthesized in plants. The ferulic acid biosynthesis is still affected by the insufficient methylation activity of caffeic acid O‐methyltransferase (COMT). In this study, we engineered COMT from Arabidopsis thaliana to match caffeic acid, and the mutant COMTN129V‐H313A‐F174L showed 4.19‐fold enhanced ...
Huai Qi Shang +7 more
wiley +1 more source
Food Frontiers, Volume 6, Issue 2, Page 801-818, March 2025.This study elucidates how the V‐shaped multicellular structuring facilitates the 3D‐biofilm formation through the LuxS‐dependent quorum‐sensing pathway, which provides an extraordinary protection mode for cellular survivability in highly acidic conditions.
Athira Venugopal +4 more
wiley +1 more source
ChemCatChem, Volume 17, Issue 4, February 17, 2025.The cascade using methionine adenosyltransferases (MATs), O‐methyltransferases (O‐MTs), and thioadenosine nucleosidase (MTAN) was utilized for the regioselective biocatalytic O‐allylation of a variety of catechols and tetrahydroisoquinolines. (S)‐Tetrahydroisoquinoline substrates were stereoselectively generated from the catecholamine dopamine and ...
Matthew T. Salinger +4 more
wiley +1 more source
Protein Science, Volume 34, Issue 2, February 2025.Abstract N‐Methylation of the peptide backbone confers pharmacologically beneficial characteristics to peptides that include greater membrane permeability and resistance to proteolytic degradation. The borosin family of ribosomally synthesized and post‐translationally modified peptides offer a post‐translational route to install amide backbone α‐N ...
Kathryn K. Crone +3 more
wiley +1 more source
STUDY OF NUCLEOSIDE DEGRADING ENZYME ACTIVITIES IN BEAN, ORGANIC BEAN, OKRA, ORGANIC OKRA, SQUASH AND ORGANIC SQUASH [PDF]
, 2016 Pyrimidine and purine nucleotide metabolism are essential for development and growth of all organisms. Nucleoside degradation reactions have been found in virtually all organisms.
Alshaiban, Shafiqa Ali
core +1 more source
Gene mining a marama bean expressed sequence tags (ESTs) database: Embryonic seed development genes and microsatellite marker identification [PDF]
, 2015 Tylosema esculentum (marama bean) is one of the underutilized legumes that have potential to provide protein and fatty acids to ensure food security in dry parts of Southern Africa.
Chimwamurombe, PM, Sheehama, EN
core +2 more sources
Induction of antiinflammatory purinergic signaling in activated human iNKT cells. [PDF]
, 2018 Invariant natural killer T (iNKT) cells are activated at sites of local tissue injury, or globally during vaso-occlusive episodes of sickle cell disease (SCD). Tissue damage stimulates production of CD1d-restricted lipid antigens that activate iNKT cells
Field, Joshua +3 more
core +1 more source
AMINO ACID SEQUENCE OF NUCLEOSIDE HYDROLASES FROM PLANTS [PDF]
, 2014 Nucleoside hydrolases are key enzymes of the purine salvage pathways of various bacteria, yeast, parasitic protozoa, insects, fish, and plants. While the structures of nucleoside hydrolases from parasitic protozoans have been extensively studied, almost
Ogorodnik, Kateryna V.
core +1 more source
SURVEY OF NUCLEOSIDE DEGRADING ENZYME ACTIVITIES IN SOYBEAN, CORN AND YELLOW LUPIN [PDF]
, 2014 Efficient pyrimidine and purine nucleotide metabolism is essential for healthy growth and development of all organisms. Significant energy cost reduction and a mutation bypass mechanism is afforded via the recycling pathways of nucleotide metabolism in ...
Ustynov, Sergiy
core +1 more source
Examination of \u3cem\u3eKlebsiella pneumoniae\u3c/em\u3e 5\u27-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase and 5-Methylthioribose Kinase [PDF]
, 2016 Klebsiella pneumoniae is an opportunistic bacterial pathogen that is emerging as a major global threat as an infectious agent. This organism, along with many other pathogens, possesses a broad suite of antibiotic resistances that can make treatment ...
Stonick, Jason Alan
core +1 more source