Results 71 to 80 of about 923,736 (263)

Pathway analysis of NAD+ metabolism [PDF]

Biochemical Journal, 2011
NAD+ is well known as a crucial cofactor in the redox balance of metabolism. Moreover, NAD+ is degraded in ADP-ribosyl transfer reactions, which are important components of multitudinous signalling reactions. These include reactions linked to DNA repair and aging.
Toni I. Gossmann, Toni I. Gossmann, Stefan Schuster, Mathias Ziegler, Luis F. de Figueiredo, Luis F. de Figueiredo   +5 more
openaire   +4 more sources

NAD+ Homeostasis and NAD+-Consuming Enzymes: Implications for Vascular Health

Antioxidants, 2023
Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous metabolite that takes part in many key redox reactions. NAD+ biosynthesis and NAD+-consuming enzymes have been attracting markedly increasing interest since they have been demonstrated to be involved in several crucial biological pathways, impacting genes transcription, cellular signaling, and ...
Roberto Campagna, Arianna Vignini
openaire   +3 more sources

A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation. [PDF]

, 2019
Nicotinamide adenine dinucleotide (NAD+)-dependent ADP-ribosylation plays important roles in physiology and pathophysiology. It has been challenging to study this key type of enzymatic post-translational modification in particular for protein poly-ADP ...
Chen, Jingwen, Cheng, Qinqin, Dai, Zhefu, Evdokimov, Nikolai M, Lam, Albert T, Louie, Stan G, Lu, Yanran, Pei, Hua, Zhang, Xiao-Nan, Zhang, Yong   +9 more
core   +1 more source

Aerial Bombing Crater Identification: Exploitation of Precise Digital Terrain Models

ISPRS International Journal of Geo-Information, 2020
Places of past conflicts and persistent objects that reflect such events often attract the attention of archaeological prospection which facilitates the construction of conflict narratives. Field prospection as a precise method for localization of aerial
Martin Dolejš, Jan Pacina, Martin Veselý, Dominik Brétt   +3 more
doaj   +1 more source

Metabolic control of mitophagy

European Journal of Clinical Investigation, Volume 54, Issue 4, April 2024.
Abstract Mitochondrial dysfunction is a major hallmark of ageing and related chronic disorders. Controlled removal of damaged mitochondria by the autophagic machinery, a process known as mitophagy, is vital for mitochondrial homeostasis and cell survival.
Andreas Zimmermann, Frank Madeo, Abhinav Diwan, Junichi Sadoshima, Simon Sedej, Guido Kroemer, Mahmoud Abdellatif   +6 more
wiley   +1 more source

Bud blight (Gemmamyces piceae) in the eastern part of the Krušné hory Mountains

Journal of Forest Science, 2020
A survey was carried out in 2013-2019 on the life cycle of the bud blight Gemmamyces piceae (Borthw.) Casagrande and the trend assessment in the infestation of the Colorado blue spruce Picea pungens Engelm. stands.
Jiří Šefl, Veronika Mottlová, Iva Schořálková   +2 more
doaj   +1 more source

Personalized Porous Gelatin Methacryloyl Sustained‐Release Nicotinamide Protects Against Noise‐Induced Hearing Loss

Advanced Science, Volume 11, Issue 12, March 27, 2024.
NAD+ decreases in cochlear after noise trauma, and nicotinamide supplementation boosts NAD+ and prevents neuroexcitatory in cochlear by round window administration. Personalized porous gelatin methacryloyl (PGMA) achieves long term drug release in cochlear, and nicotinamide encapsulated PGMA enhances mitochondria and synapse function, and protects ...
Baoyi Feng, Tingting Dong, Xinyu Song, Xiaofei Zheng, Chenxi Jin, Zhenzhe Cheng, Yiqing Liu, Wenjie Zhang, Xueling Wang, Yong Tao, Hao Wu   +10 more
wiley   +1 more source

Miasta nad najdłuższymi polskimi rzekami

Studia Regionalne i Lokalne
W Polsce jest prawie tysiąc miast, w tym wiele miast nadrzecznych, które w pracach naukowych najczęściej są opisywane i analizowane oddzielnie, jako indywidualny przedmiot badań.
Miasta nad najdłuższymi polskimi rzekami
doaj   +1 more source

Unusual Enzymatic Hydrolysis of NAD by Solubilized Form of NAD+ Glycohydrolase.

Chemical and Pharmaceutical Bulletin, 2002
Using solubilized form (sNADase) of membrane-bound porcine brain NAD(+) glycohydrolase (pNADase), the NADase-catalyzed hydrolysis and transglycosidation reactions of NAD (1) were examined. Unexpectedly, products in the reactions were found to be nicotinamide (5'-O-diphosphono)-beta-D-ribofuranoside (4) and adenosine (5).
Masanori Hatakeyama, Shuichi Tono-oka
openaire   +3 more sources

Postoj studentů sociální pedagogiky k homoparentálním rodinám [PDF]

Sociální Pedagogika
The paper is focused on the research of the attitude of the students of the Bachelor's and Master's degree programmes in social pedagogy from the J. E.
Pavel Doulík, Jiří Škoda, Barbora Čechová, Zuzana Procházková   +3 more
doaj   +1 more source