Results 81 to 90 of about 989,508 (337)

Corporate Social Responsibility of Organizations as Part of a Quality Management System

Production Engineering Archives, 2021
The paper deals with the topic of social responsibility in selected organizations in the Czech Republic. This topic is mainly associated with the requirements for economical and ecological production.
Střihavková Elena, Svobodová Jaroslava, Vysloužilová Daniela   +2 more
doaj   +1 more source

NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis. [PDF]

, 2019
The 5' end of a eukaryotic mRNA transcript generally has a 7-methylguanosine (m7G) cap that protects mRNA from degradation and mediates almost all other aspects of gene expression.
Cai, Zongwei, Chen, Xuemei, Ni, Min, Shao, Xiaojian, Xia, Yiji, Zhang, Hailei, Zhang, Shoudong, Zhong, Huan   +7 more
core  

Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair‐Deficient 3xTg/POLβ+/− Alzheimer Disease Mouse Model

Journal of Neurochemistry, Volume 169, Issue 1, January 2025.
Alzheimer disease causes neurodegeneration of the hippocampus. It impedes brain glucose metabolism and impairs mitochondrial energy along electron transport chain (ETC). Will a ketone‐based diet with nicotinamide riboside restore hippocampal energy in an Alzheimer mouse model?
Robert Pawlosky, Tyler G. Demarest, M. Todd King, Darlene Estrada, Richard L. Veech, Vilhelm A. Bohr   +5 more
wiley   +1 more source

PGC‐1a integrates a metabolism and growth network linked to caloric restriction

Aging Cell, Volume 18, Issue 5, October 2019., 2019
We show that activation of mitochondria via PGC‐1a in cells impinges on diverse functions including chromatin remodeling and RNA processing. We suggest that this PGC‐1a‐directed network is implicated in the mechanisms of delayed aging by caloric restriction.
Karl N. Miller, Josef P. Clark, Stephen A. Martin, Porsha R. Howell, Maggie S. Burhans, Spencer A. Haws, Nathan B. Johnson, Timothy W Rhoads, Derek M. Pavelec, Kevin W. Eliceiri, Avtar S. Roopra, James M. Ntambi, John M. Denu, Brian W. Parks, Rozalyn M. Anderson   +14 more
wiley   +1 more source

Aerial Bombing Crater Identification: Exploitation of Precise Digital Terrain Models

ISPRS International Journal of Geo-Information, 2020
Places of past conflicts and persistent objects that reflect such events often attract the attention of archaeological prospection which facilitates the construction of conflict narratives. Field prospection as a precise method for localization of aerial
Martin Dolejš, Jan Pacina, Martin Veselý, Dominik Brétt   +3 more
doaj   +1 more source

Finding new directors: The Law of supply and demand [PDF]

, 1980
Illustrations not included in Web ...
Nad, Abraham
core   +1 more source

“Give Me Back My Children!”: Traumatic Reenactment and Tenuous Democratic Public Spheres [PDF]

, 2014
In this essay, I briefly review the cultural history of “historical reenactments” and consider one 19th century prelude to present-day traumatic reenactments.
Armstrong, Auslander, Baudrillard, Clifford, Foucault, Handler, Levi-Strauss, Nielsen, Taylor, Turner, Woolfork   +10 more
core   +2 more sources

Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila

Aging Cell, Volume 23, Issue 4, April 2024.
Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy, Reyhan Westbrook, Austin King, Nick Khosravian, Neeraj Ochaney, Tagide DeCarvalho, Qinchuan Wang, Yuqiong Yu, Qiao Huang, Adam Said, Michael Abadir, Cissy Zhang, Pratik Khare, Jennifer E. Fairman, Anne Le, Ginger L. Milne, Fernando J. Vonhoff, Jeremy D. Walston, Peter M. Abadir   +18 more
wiley   +1 more source

Biodistribution and toxicity assessment of methoxyphenyl phosphonium carbosilane dendrimers in 2D and 3D cell cultures of human cancer cells and zebrafish embryos

Scientific Reports, 2023
The consideration of human and environmental exposure to dendrimers, including cytotoxicity, acute toxicity, and cell and tissue accumulation, is essential due to their significant potential for various biomedical applications.
Zuzana Žmudová, Zuzana Šanderová, Michaela Liegertová, Stanislav Vinopal, Regina Herma, Luděk Sušický, Monika Müllerová, Tomáš Strašák, Jan Malý   +8 more
doaj   +1 more source

No significant retinal damage induced by major orthopedic surgery - a pilot study

Biomedical Papers, 2022
Background. Perioperative visual loss is one of the rare but devastating complications of anesthesia and surgery. The incidence of less severe or even subclinical postoperative visual dysfunction is unknown.
Tomas Parizek, Roman Skulec, Ivana Liehneova, Petr Prasek, Vladimir Cerny   +4 more
doaj   +1 more source