Results 261 to 270 of about 139,842 (299)

Activation of calmodulin-dependent NAD+ kinase by trypsin

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982
Sea urchin egg NAD+ kinase (ATP:NAD+ 2'-phosphotransferase, EC 2.7.1.23), a calmodulin-dependent enzyme, can be activated by a moderate treatment with trypsin in a similar fashion to calmodulin. Stimulation by trypsin is dependent on its concentration (half-maximal dose: 1.5 microgram/ml) but independent of the presence of calcium.
L, Meijer, P, Guerrier
openaire   +2 more sources

[119] NAD+ kinase in liver tissue

1971
Publisher Summary This chapter discusses the assay method, purification procedure, and properties of the enzyme nicotinamide adenine dinucleotide (NAD + ) kinase in frozen rat and calf liver tissue. The nicotinamide adenine dinucleotide phosphate (NADP + ) formed in the reaction mixture is assayed by method based on the measurement of the change in ...
L.S. Dietrich, I.L. Yero
openaire   +1 more source

[ATP and polyphosphate-dependent bacterial NAD+-kinases].

Prikladnaia biokhimiia i mikrobiologiia, 2000
Measurable levels of activity of NAD+ kinases of actinomycetes Micrococcus luteus and Corynebacterium ammoniagenes were observed after substituting inorganic tripolyphosphate for ATP, whereas the enzyme from the eubacterium Escherichia coli was not active with this substrate. Gradient PAGE found two molecular isoforms of NAD+ kinase in C.
S Iu, Filippovich, T P, Afanas'eva, G P, Bachurina, M S, Kritskiĭ   +3 more
openaire   +3 more sources

NAD Kinase Is an AKT Substrate

Cancer Discovery, 2019
Abstract AKT-mediated phosphorylation of NAD kinase induces synthesis of NADP+ and NADPH.
openaire   +1 more source

Compact NAD mimics as selective inhibitors of NAD kinases

2009
We have examined sequence diversity of 147 co-crystal structures of proteins utilizing NAD as a cofactor or as a substrate. Most of these proteins bind NAD in an extended conformation (e.g. the distance between the adenine 6-amino group of NAD and the nicotinamide amide carbon is 16 Å or more). However, there are clear exceptions to this general trend.
PETRELLI, Riccardo, SHAM Y. Y, CHEN L, FELCZAK, K, DI STEFANO M, MAGNI G, PANKIEWICZ K. W.   +6 more
openaire   +1 more source

Immobilization of NAD Kinase

Annals of the New York Academy of Sciences, 1984
X S, Ji, H X, Li, Z Y, Yuan, S H, Liu
openaire   +2 more sources

PROBING BINDING REQUIREMENTS OF NAD KINASE WITH MODIFIED NAD ANALOGUES

2012
NAD kinase (NADK) catalyzes a magnesium-dependent phosphorylation of the 2′-hydroxyl group of the adenosine ribose moiety of nicotinamide adenine dinucleotide (NAD) using ATP or inorganic polyphosphates as phosphoryl donors to give NADP. There are two classes of the enzyme, one is specific for NAD+ and the other also phosphorylates NADH.
PETRELLI, Riccardo, VITA, PATRIZIA, TORQUATI, ILARIA, Krzysztof Felczak, Palmarisa Franchetti, Mario Grifantini, Michele Di Stefano, Giulio Magni, Krzysztof W. Pankiewicz, CAPPELLACCI, Loredana   +9 more
openaire   +1 more source

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly  

[Thermoinactivation of NAD-kinase from rabbit liver].

Biokhimiia (Moscow, Russia), 1995
Thermal inactivation of homogeneous NAD-kinase and its partially purified preparation containing NAD-kinase in complex with glutamate dehydrogenase has been studied. The complex is more resistant to thermal inactivation in comparison with isolated NAD-kinase; its inactivation consists in irreversible dissociation preceded by a period of constant ...
G V, Afanas'eva, E R, Bulygina, V I, Telepneva   +2 more
openaire   +1 more source

[Interaction of NAD-kinase with glutamate dehydrogenase].

Biokhimiia (Moscow, Russia), 1988
The formation of a NAD kinase-glutamate dehydrogenase complex was studied, using three independent methods. It was found that the polymeric form of glutamate dehydrogenase is involved in the formation of a complex with NAD kinase. Both the oligomeric and monomeric (subunit) forms of NAD kinase were shown to possess the ability to form complexes with ...
O L, Voronina, E R, Bulygina, V I, Telepneva   +2 more
openaire   +1 more source