Results 201 to 210 of about 268,882 (295)

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Benign prostatic hyperplasia nodules in patients treated with celecoxib and/or finasteride have reduced levels of NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, a mitochondrial protein essential for efficient function of the electron transport chain. [PDF]

Prostate
Liu TT, Igarashi T, El-Khoury N, Ihejirika N, Paxton K, Jaumotte J, Dhir R, Hudson CN, Nelson JB, DeFranco DB, Yoshimura N, Wang Z, Pascal LE.   +12 more
europepmc   +1 more source

Reactive oxygen species, antioxidants and the regulation of plant development

The FEBS Journal, EarlyView.
The regulation of axillary bud outgrowth by the interplay between phytohormone and redox signals. Axillary bud outgrowth is regulated by cellular energy status and the balance between phytohormones, notably abscisic acid (ABA) and gibberellic acid (GA).
Juwita R. Dewi, Christine H. Foyer, Michael J. Considine   +2 more
wiley   +1 more source

Energetic dysregulations in psychotic disorders: Targets for new therapeutics

The FEBS Journal, EarlyView.
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson, Kai‐Christian Sonntag, Thao Do Vy Le, Kaitlin Shannon, Chao Wang, Fei Du, Xi Chen, Donna McPhie, Dost Ongur, Bruce Cohen, Virginie‐Anne Chouinard   +10 more
wiley   +1 more source

Polymorphic myopathological findings in a 77‐year‐old woman with oculo‐bulbo‐facial and distal weakness

Brain Pathology, EarlyView.
Michele Tosi, Angela Puma, Elena Faedo, Gianmarco Severa, Luisa Villa, Sabrina Sacconi, Edoardo Malfatti   +6 more
wiley   +1 more source

A comprehensive study on ferredoxin isoforms in the cyanobacterium Synechocystis sp. PCC 6803

The FEBS Journal, EarlyView.
Ferredoxins are small FeS cluster‐containing proteins that play a central role in distributing electrons within the cell. The cyanobacterium Synechocystis sp. PCC 6803 contains several ferredoxin isoforms and their biophysical properties (UV/Vis and EPR spectra, Em potential), expression patterns, and interactions with the electron donors photosystem I
Marko Boehm, Drazenka Svedruzic, Carolyn E. Lubner, Jens Appel, David W. Mulder, Effie C. Kisgeropoulos, Vanessa Hueren, Katharina Spengler, Vivek S. Bharadwaj, Zhanjun Guo, Anastasia E. Ledinina, Darja Deobald, Lorenz Adrian, Paul W. King, Kirstin Gutekunst   +14 more
wiley   +1 more source

Novel mitochondrial complex I-inhibiting peptides restrain NADH dehydrogenase activity. [PDF]

Sci Rep, 2019
Xue YP, Kao MC, Lan CY.
europepmc   +1 more source

Mitochondrial Pentatricopeptide Repeat Protein, EMB2794, Plays a Pivotal Role in NADH Dehydrogenase Subunit nad2 mRNA Maturation in Arabidopsis thaliana. [PDF]

Plant Cell Physiol, 2020
Marchetti F, Cainzos M, Shevtsov S, Córdoba JP, Sultan LD, Brennicke A, Takenaka M, Pagnussat G, Ostersetzer-Biran O, Zabaleta E.   +9 more
europepmc   +1 more source

Hydrothermal origin of metabolic phosphorylation

The FEBS Journal, EarlyView.
Serpentinizing hydrothermal vents are candidate sites for biochemical origins. They generate extremely reducing conditions, depositing phosphite (HPO32−) and transition metals, including palladium, in the native (zero‐valent) state. Schlikker et al.
Manon L. Schlikker, Nadja K. Hoffmann, Sabine Metzger, Jorge Moral‐Pombo, Harun Tüysüz, William F. Martin   +5 more
wiley   +1 more source

TIM‐3 Functions as an Activator of NK Cells in GBM and Can Be Upregulated by Torin‐1: Implications for Exogenous NK Cell Transplantation

Immunology, EarlyView.
Unlike generalized mTOR inhibitors, Torin‐1 uniquely drives compensatory upregulation of TIM‐3 on human NK cells, shielding them from immunosuppression while concurrently inhibiting glioblastoma (GBM) growth. Selecting or preconditioning ex vivo NK cell products for high TIM‐3 expression can offer a combination strategy for adoptive cell therapy in GBM.
Yuning Liu, Tram Dao, Shambhavi Borde, Diana Dinh, Sofia Lombardi, Sandra Torregrosa‐Allen, Haley A. Harper, Veronika Slivova, Aaron Cohen‐Gadol, MacKenzie McIntosh, Bennet D. Elzey, Sandro Matosevic   +11 more
wiley   +1 more source