Results 31 to 40 of about 465,834 (342)

Influence of electrode potential, pH and NAD+ concentration on the electrochemical NADH regeneration

Scientific Reports, 2022
Electrochemical NAD+ reduction is a promising method to regenerate NADH for enzymatic reactions. Many different electrocatalysts have been tested in the search for high yields of the 1,4-isomer of NADH, the active NADH, but aside from electrode material,
Emad Aamer, Jorg Thöming, Michael Baune, Nicholas Reimer, Ralf Dringen, Manuela Romero, Ingmar Bösing   +6 more
doaj   +1 more source

Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity

Angewandte Chemie, 2018
The generation of ATP through oxidative phosphorylation is an essential metabolic function for Mycobaterium tuberculosis (Mtb), regardless of the growth environment.
Michael B. Harbut, Baiyuan Yang, Renhe Liu, T. Yano, C. Vilchèze, Bo Cheng, Jonathan W Lockner, Hui Guo, Chenguang Yu, S. Franzblau, H. Mike Petrassi, William R. Jacobs, H. Rubin, A. Chatterjee, Feng Wang   +14 more
semanticscholar   +1 more source

Graphene and graphene oxide induce ROS production in human HaCaT skin keratinocytes: the role of xanthine oxidase and NADH dehydrogenase.

Nanoscale, 2018
The extraordinary physicochemical properties of graphene-based nanomaterials (GBNs) make them promising tools in nanotechnology and biomedicine. Considering the skin contact as one of the most feasible exposure routes to GBNs, the mechanism of toxicity ...
M. Pelin, L. Fusco, Cristina Martín, S. Sosa, Javier Frontiñán-Rubio, J. González-Domínguez, M. Durán-Prado, E. Vázquez, M. Prato, A. Tubaro   +9 more
semanticscholar   +1 more source

Photosystem I cyclic electron flow via chloroplast NADH dehydrogenase-like complex performs a physiological role for photosynthesis at low light

Scientific Reports, 2015
Cyclic electron transport around photosystem I (PS I) was discovered more than a half-century ago and two pathways have been identified in angiosperms.
W. Yamori, T. Shikanai, A. Makino
semanticscholar   +1 more source

Quantifying NAD(P)H production in the upper Entner–Doudoroff pathway from Pseudomonas putida KT2440

FEBS Open Bio, 2015
Despite the lack of biochemical information, all available in silico metabolic models of Pseudomonas putida KT2440 consider NADP as the only cofactor accepted by the glucose‐6‐phosphate dehydrogenases.
Karel Olavarria, Marina Pupke Marone, Henrique da Costa Oliveira, Juan Camilo Roncallo, Fernanda Nogales da Costa Vasconcelos, Luiziana Ferreira da Silva, José Gregório Cabrera Gomez   +6 more
doaj   +1 more source

From identification of fluorescent flavoproteins to mitochondrial redox indicators in intact tissues [PDF]

Journal of Innovative Optical Health Sciences, 2014
Development of the use of flavin and nicotinamide-adenine nucleotide fluorescence in monitoring the redox state of the free mitochondrial NADH/NAD+ couple in cells, tissues and organs is reviewed.
Ilmo E. Hassinen
doaj   +1 more source

Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells

Cell Reports, 2018
Summary: Highly glycolytic cancer cells prevent intracellular acidification by excreting the glycolytic end-products lactate and H+ via the monocarboxylate transporters 1 (MCT1) and 4 (MCT4).
Don Benjamin, Dimitri Robay, Sravanth K. Hindupur, Jens Pohlmann, Marco Colombi, Mahmoud Y. El-Shemerly, Sauveur-Michel Maira, Christoph Moroni, Heidi A. Lane, Michael N. Hall   +9 more
doaj   +1 more source

Physiological relevance, localization and substrate specificity of the alternative (type II) mitochondrial NADH dehydrogenases of Ogataea parapolymorpha

Frontiers in Microbiology
Mitochondria from Ogataea parapolymorpha harbor a branched electron-transport chain containing a proton-pumping Complex I NADH dehydrogenase and three Type II NADH dehydrogenases (NDH-2).
Hannes Juergens, Álvaro Mielgo-Gómez, Albert Godoy-Hernández, Jolanda ter Horst, Janine M. Nijenhuis, Duncan G. G. McMillan, Duncan G. G. McMillan, Robert Mans   +7 more
doaj   +1 more source

A Toolbox for Quantitative Gene Expression in Varroa destructor: RNA Degradation in Field Samples and Systematic Analysis of Reference Gene Stability.

PLoS ONE, 2016
Varroa destructor is the major pest of Apis mellifera and contributes to the global honey bee health crisis threatening food security. Developing new control strategies to combat Varroa will require the application of molecular biology, including gene ...
Ewan M Campbell, Catriona H McIntosh, Alan S Bowman   +2 more
doaj   +1 more source

Effect of different NADH oxidase levels on glucose metabolism by Lactococus lactis : kinetics of intracellular metabolite pools determined by in vivo nuclear magnetic resonance

, 2002
Three isogenic strains of Lactococcus lactis with different levels of H2O-forming NADH oxidase activity were used to study the effect of oxygen on glucose metabolism: the parent strain L.
Vos, W.M., de, Kleerebezem, M., Hugenholtz, J., Ramos, A., Santos, H., Neves, A.R., Costa, H., Swam, I.I., van   +7 more
core   +1 more source