Results 41 to 50 of about 465,834 (342)

NADH dehydrogenase complex I is overexpressed in incipient metastatic murine colon cancer cells. [PDF]

Oncol Rep, 2019
Colon cancer is one of the most frequently occurring types of cancers in the world. Primary tumours are treated very efficiently, but the metastatic cases are known to have severe outcomes.
Marquez J, Kratchmarova I, Akimov V, Unda F, Ibarretxe G, Clerigué AS, Osinalde N, Badiola I.   +7 more
europepmc   +3 more sources

NADH Dehydrogenases in Pseudomonas aeruginosa Growth and Virulence [PDF]

Frontiers in Microbiology, 2019
Pseudomonas aeruginosa is an opportunistic human pathogen with a complex respiratory chain. The bacterium is predicted to express three NADH:ubiquinone oxidoreductases (NDH-1, NDH-2 and Nqr). We created deletions strains of the predicted NADH:ubiquinone oxidoreductases alone, and in combination to determine the respective roles of the NADH ...
Angela Torres, Naomi Kasturiarachi, Matthew DuPont, Vaughn S. Cooper, Jennifer Bomberger, Anna Zemke   +5 more
openaire   +3 more sources

Uncovering evolutionary and phylogenetic relationships in Glyptothorax species through comparative mitochondrial genomics

Journal of Genetic Engineering and Biotechnology
The mitochondrial genome serves as a crucial molecular marker for studying phylogenetic relationships and molecular evolution in fish. Despite their ecological significance in freshwater ecosystems, Glyptothorax fishes have limited evolutionary research,
Somasundaram Iyyappan, Suvadip Ghara, Irfan Ahmad Bhat, Irfan Ahmad Khan, Mohd Ashraf Rather   +4 more
doaj   +1 more source

Lactate Limits T Cell Proliferation via the NAD(H) Redox State

Cell Reports, 2020
Summary: Immune cell function is influenced by metabolic conditions. Low-glucose, high-lactate environments, such as the placenta, gastrointestinal tract, and the tumor microenvironment, are immunosuppressive, especially for glycolysis-dependent effector
William J. Quinn, III, Jing Jiao, Tara TeSlaa, Jason Stadanlick, Zhonglin Wang, Liqing Wang, Tatiana Akimova, Alessia Angelin, Patrick M. Schäfer, Michelle D. Cully, Caroline Perry, Piotr K. Kopinski, Lili Guo, Ian A. Blair, Louis R. Ghanem, Michael S. Leibowitz, Wayne W. Hancock, Edmund K. Moon, Matthew H. Levine, Evgeniy B. Eruslanov, Douglas C. Wallace, Joseph A. Baur, Ulf H. Beier   +22 more
doaj   +1 more source

A Redox-Neutral, Two-Enzyme Cascade for the Production of Malate and Gluconate from Pyruvate and Glucose

Applied Sciences, 2021
A triple mutant of NADP(H)-dependent malate dehydrogenase from thermotolerant Thermococcus kodakarensis has an altered cofactor preference for NAD+, as well as improved malate production compared to wildtype malate dehydrogenase.
Ravneet Mandair, Pinar Karagoz, Roslyn M. Bill   +2 more
doaj   +1 more source

In Planta Mutagenesis of Src Homology 3 Domain-like Fold of NdhS, a Ferredoxin-binding Subunit of the Chloroplast NADH Dehydrogenase-like Complex in Arabidopsis

Journal of Biological Chemistry, 2013
Background: NdhS is a ferredoxin-binding subunit of chloroplast NADH dehydrogenase-like (NDH) complex. Results: Mutagenesis of the Src homology 3-like domain of NdhS revealed that its positively charged pocket is required for high affinity binding of ...
Hiroshi Yamamoto, T. Shikanai
semanticscholar   +1 more source

NADH-Free Electroenzymatic Reduction of CO₂ by Conductive Hydrogel-Conjugated Formate Dehydrogenase

, 2019
The electrocatalytic reduction of CO2 under low overpotential and mild conditions using redox enzyme is a propitious route for carbon capture and conversion.
Tae-Doo Kim (6714002), Youngjun Lee, Jung-Kul Lee, Su Keun Kuk, Chan Beum Park, Krishnasamy Gopinath (6713999), Raushan K. Singh (1325724), Jung-Kul Lee (451432), Raushan K. Singh, Su Keun Kuk (4405879), Tae-Doo Kim, Youngjun Lee (1941202), Woo Seok Choi, Woo Seok Choi (1351647), Chan Beum Park (1579897), Krishnasamy Gopinath   +15 more
core   +1 more source

Functional characterization of SlscADH1, a fruit-ripening associated short-chain alcohol dehydrogenase of tomato [PDF]

, 2012
A tomato short-chain dehydrogenase-reductase (SlscADH1) is preferentially expressed in fruit with a maximum expression at the breaker stage while expression in roots, stems, leaves and flowers is very weak.
Moummou, Hanane, Chervin, Christian, Latché, Alain, Pech, Jean-Claude, Benichou, Mohamed, Tonfack, Libert Brice, Ginies, Christian, Van der Rest, Benoît, Youmbi, Emmanuel   +8 more
core   +1 more source

Self-sufficient asymmetric reduction of β-ketoesters catalysed by a novel and robust thermophilic alcohol dehydrogenase co-immobilised with NADH [PDF]

, 2021
Agradecimientos FLG, JRM y JMG agradecen la financiación del proyecto HOTZYMES de la Unión Europea (UE) (acuerdo de subvención nº 829162) en el marco del programa H2020-FETOPEN.
Rocha Martín, Javier, Orrego, Alejandro, Sanchez-Costa, Mercedes, Orrego, A.H., Velasco-Lozano, Susana, Velasco-Lozano, S., Andrés-Sanz, Daniel, Berenguer Carlos, José, Berenguer, José, Sánchez-Costa, M., Rocha-Martín, J., López-Gallego, F., Andrés-Sanz, D., Guisán, José M., López-Gallego, Fernando, Guisan, J.M.   +15 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source