Results 161 to 170 of about 62,836 (259)

In vitro and in vivo metabolism profiles of cathinone and pseudoephedrine: Discrimination between khat and pseudoephedrine uses

Journal of Forensic Sciences, Volume 71, Issue 4, Page 1758-1766, July 2026.
Abstract In the present study, the metabolism of khat (Catha edulis) and pseudoephedrine was compared with the aim of identifying objective criteria that could be used to discriminate between them for forensic and doping‐control purposes. An in vitro study using human liver microsomes and an in vivo study using rat urine were performed under harmonized
Jong Suk Park, Jun Sang Yu, Yejin Kim, Hee Seung Kim, Jae Chul Cheong, Jin Young Kim, Hye Hyun Yoo   +6 more
wiley   +1 more source

Flavonoids from <i>Elsholtzia ciliata</i> restore redox electron flow and metabolic signaling via PTP1B inhibition in muscle and liver cells. [PDF]

J Enzyme Inhib Med Chem
Lee SS, Kim JH, Bang K, Yu J, Kim YG, Kim SY, Lee IS, Yoo YC.   +7 more
europepmc   +1 more source

Biological Safety and Functional Properties of Açaí Seed Extract: Antioxidant Capacity and Prebiotic Potential

Journal of Food Science, Volume 91, Issue 7, July 2026.
ABSTRACT Açaí (Euterpe oleracea) is widely recognized as a functional food due to its nutritional value and abundance of bioactive compounds. Its seeds, representing approximately 80%–95% of the fruit mass, constitute an abundant agro‐industrial byproduct with promising biotechnological potential.
Marcelo Pereira da Silva Junior, Amanda de Jesus Alves Miranda, Ana Laura Gagliardi, Isabelle Guerreiro Moreira, Maria Eduarda Santos Camaceti, Mateus Kawata Salgaço, Kátia Sivieri, Cláudia Quintino da Rocha, Flávia Aparecida Resende   +8 more
wiley   +1 more source

Metformin Sensitizes PTEN-deficient Prostate Cancer to PARP Inhibitors by Rebuilding NADP⁺ Homeostasis. [PDF]

Int J Biol Sci
Hao X, Chao Z, Peng H, Guo X, Zheng S, Zhang C, Ding H, Wang Y, Xi Z, Gao Y, Qu G, Zhu Y, Chen Z, Lan P, Li L, Wang Z.   +15 more
europepmc   +1 more source

Gut Metabolism Links Precision Nutrition, Exercise, and Healthspan in Drosophila melanogaster

Aging Cell, Volume 25, Issue 7, July 2026.
This study reveals that precision nutrition, exercise, and gut microbiota pathways synergistically regulate host metabolism, redox balance, and arginine‐spermidine metabolism, enhancing antioxidant defenses and mitochondrial stabilization to combat aging.
Fangchao Wei, Shiyu Liu, Yudong Sun, Haipeng Huang, Juan Liu, Fengzhong Wang, Bei Fan   +6 more
wiley   +1 more source

Changes in the brain [NAD⁺]/[NADH] and [NADPH]/[NADP⁺] with aging and anti-aging dietary restriction. [PDF]

Front Aging Neurosci
Jamerson LE, Bradshaw TD, Bradshaw PC.
europepmc   +1 more source

AKR1C3 Binds β‐Trcp to Promote the Degradation of TFRC to Protect Hepatocellular Carcinoma From Ferroptosis

Cancer Science, Volume 117, Issue 7, Page 1867-1882, July 2026.
In this study, we show that aldo‐keto reductase family 1 member C3 (AKR1C3), a protein highly expressed in ferroptosis resistant hepatocellular carcinoma cells, acts as an enzyme‐independent scaffold protein by promoting the nuclear export of β‐transducin repeat protein (β‐TrCP) and its binding to transferrin receptor (TFRC) in an enzyme‐independent ...
Lei Qi, Jingyi Hua, Di Pan, Wanwan Yang, Geng Tian, Fangyu Ye, Lingxiang Liu, Yuhan Mao, Qinglong Guo, Haopeng Sun, Li Zhao   +10 more
wiley   +1 more source

Proteomics-Based Study of Potential Emphysema Biomarkers Reveals Systemic Redox System and Extracellular Matrix Component Dysregulation. [PDF]

Diagnostics (Basel)
Salai G, Novak R, Hrkač S, Pustka V, Potěšil D, Zdráhal Z, Ljubicic D, Grgurević L.   +7 more
europepmc   +1 more source

Gametophyte Thermal Priming Modifies the Transcriptomic Heat Stress Response of Sporophyte Progeny in Saccharina latissima

Evolutionary Applications, Volume 19, Issue 7, July 2026.
ABSTRACT Saccharina latissima (sugar kelp) is a brown macroalga that forms kelp forests along North Atlantic coasts, playing a key role in coastal ecosystems. It is also of growing economic importance as the dominant species used in European kelp aquaculture.
Anne M. L. Nilsen, Niko Steiner, Inka Bartsch, J. Mark Cock, Alexander O. Jueterbock   +4 more
wiley   +1 more source

Mitochondrial NAD kinase Pos5 is required for CoQ biosynthesis in yeasts. [PDF]

PLoS One
Nishihara S, Nishida I, Matsuo Y, Kaino T, Kawamukai M.   +4 more
europepmc   +1 more source