Results 171 to 180 of about 75,190 (277)

MicroRNA–mRNA Networks in Skeletal Muscle of Tailored Pig Models for Dystrophinopathies

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X‐linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD‐causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression.
Sarah Reschke, Alexander Graf, Frieder Hadlich, Florian Jaudas, Thomas Fröhlich, Michael Stirm, Nikolai Klymiuk, Stefan Krebs, Eckhard Wolf, Asghar Ali   +9 more
wiley   +1 more source

A cryptic allosteric pocket shapes isoform-selective inhibition of human malic enzymes. [PDF]

Protein Sci
Krinkel BA, Yosaatmadja Y, Slayton MD, Krinkel A, Copping J, Jeon JH, Eu J, Kohagen K, Ashoorzadeh A, Smaill J, Flanagan J, Walker C, Merajver SD, Loomes K, Squire CJ.   +14 more
europepmc   +1 more source

Glutamine Metabolism in Health and Diseases

MedComm, Volume 7, Issue 10, October 2026.
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding, Fan Tong, Jing Zeng, Chun‐Ping Cui   +3 more
wiley   +1 more source

The urinary tract commensal <i>Peptoniphilus</i> spp. encodes a novel 17β-hydroxysteroid dehydrogenase. [PDF]

Appl Environ Microbiol
Binion B, Ahmad S, Wang T, Tang E, Barnick B, Olukoya D, Mbuvi P, Dutta D, Erdman JW, Gaskins HR, Yang G, Irudayaraj J, Ridlon JM.   +12 more
europepmc   +1 more source

Antioxidant Responses to Dietary Supplementation With Non‐Enriched and Selenium‐Enriched Mushrooms and Selenized Yeast in Piglets

Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.
The findings highlight tissue‐specific responses to dietary selenium supplementation, with hepatic antioxidant modulation occurring without changes in plasma parameters, while selenium deposition patterns differed among tissues, emphasizing the complex relationship between selenium sources, metabolism, and antioxidant defense.
Diene France de de Souza, Gabriel Cipriano Rocha, Dairon Pérez Fuentes, Lucas Eduardo Oliveira Porto, Pedro Vitoriano Oliveira, Marliane de Cássia Soares da Silva, Maria Catarina Megumi Kasuya, Maiane de Paula Alves, Monique Renon Eller   +8 more
wiley   +1 more source

Metabolic imaging for gamete and embryo assessment through advanced microscopy technologies: a novel avenue for artificial intelligence? [PDF]

Hum Reprod
Horta F, Sakkas D, Handley S, Xiong Y, Mihalas B, Deans R, Hart RJ, Gilchrist RB, Goldys EM.   +8 more
europepmc   +1 more source

Two distinct alcohol dehydrogenase classes mediate bacterial 2‐hydroxyethylphosphonate catabolism

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Phosphonates are molecules containing a direct carbon‐phosphorus bond. In nature, these compounds are produced by a variety of organisms, and many environmental microbes are able to degrade specific phosphonates and feed on them. This work focuses on 2‐hydroxyethylphosphonate (HEP)—a natural compound that is found frequently in the environment,
Francesca Piazza, Marianna Rodella, Nicholas Salanti, Giovanni Merici, Elisa Rossi, Claudio Rivetti, Florian Götzinger, Katharina Pallitsch, Alessio Peracchi   +8 more
wiley   +1 more source

Defining Rational Photoelectron Routing for Targeted Intracellular Energy Transfer. [PDF]

Angew Chem Int Ed Engl
Wang H, Li J, Feng Y, Wang L, He D, Zeng C, Cai Z, Xiao K, Wang B.   +8 more
europepmc   +1 more source

Strong‐Acid Weathering in a Carbonate‐Siliciclastic Cropland Diminishes Removal of CO2 From the Atmosphere Without Becoming a CO2 Source

Journal of Geophysical Research: Biogeosciences, Volume 131, Issue 10, October 2026.
Abstract One strategy to remove carbon dioxide (CO2) from the atmosphere is to accelerate weathering in croplands by adding powdered rock. Both silicate and carbonate minerals can be effective as amendments, but strong acids from rain and fertilizer diminish CO2 removal and can promote degassing of CO2 from carbonate minerals (geogenic CO2).
Michael J. Forgeng, Jonathan M. Duncan, Caitlin A. Hodges, Jason Kaye, Brandon Forsythe, Timothy S. White, Susan L. Brantley   +6 more
wiley   +1 more source

Functional characterization of 3β-hydroxysteroid dehydrogenases in Asiatic toad reveals an efficient broad substrate specificity of Bg-3βHSD2. [PDF]

Biosci Rep
Meng Q, Hu Y, Chen W, Xiao C, Yang L, Wang R, Zhang B, Zhao S, Wang Z.   +8 more
europepmc   +1 more source