NADP+ reduction by human lymphocytes [PDF]
Clinical and Experimental Immunology, 1990 SUMMARY The hexose monophosphate shunt (HMPS) is known to be responsible for the reduction of NADP+ by lymphocytes. We tried to find other enzymatic systems that might provide the lymphocytes with NADPH. By measuring the absorbance at 340 nm we noted that the addition of NADP+ to a preparation of disrupted lymphocytes resulted in the ...
A, Klein +3 more
openaire +4 more sources
A milestone in C4 carbon concentration mechanism evolution: structural remodeling of NADP-malic enzyme in Poaceae. [PDF]
Mol Biol EvolBöhm JM +13 more
europepmc +2 more sources
Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra [PDF]
, 2007 Population surveys for niacin deficiency are normally based on clinical signs or on biochemical measurements of urinary niacin metabolites. Status may also be determined by measurement of whole blood NAD and NADP concentrations. To compare these methods,
Cheung, E +5 more
core +2 more sources
Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells [PDF]
, 2009 The goal was to determine whether endogenous cytosolic NAD(P)H:quinone oxidoreductase 1 (NQO1) preferentially uses NADPH or NADH in intact pulmonary arterial endothelial cells in culture.
Bongard, Robert D +3 more
core +2 more sources
Measurement of Chloroplastic NAD Kinase Activity and Whole Tissue NAD Kinase Assay
Bio-Protocol, 2020 Nicotinamide adenine dinucleotide phosphate (NADP) synthesis requires nicotinamide adenine dinucleotide (NAD) kinase activity, substrate NAD and ATP.
Yuma Ishikawa +2 more
doaj +1 more source
Determinants of nucleotide-binding selectivity of malic enzyme. [PDF]
PLoS ONE, 2011 Malic enzymes have high cofactor selectivity. An isoform-specific distribution of residues 314, 346, 347 and 362 implies that they may play key roles in determining the cofactor specificity. Currently, Glu314, Ser346, Lys347 and Lys362 in human c-NADP-ME
Ju-Yi Hsieh +2 more
doaj +1 more source
Identification and evolution of C4 photosynthetic pathway genes in plants
BMC Plant Biology, 2020 Background NADP-malic enzyme (NAPD-ME), and pyruvate orthophosphate dikinase (PPDK) are important enzymes that participate in C4 photosynthesis. However, the evolutionary history and forces driving evolution of these genes in C4 plants are not completely
Weiping Shi +7 more
doaj +1 more source
Divergent evolution of protein conformational dynamics in dihydrofolate reductase. [PDF]
, 2013 Molecular evolution is driven by mutations, which may affect the fitness of an organism and are then subject to natural selection or genetic drift. Analysis of primary protein sequences and tertiary structures has yielded valuable insights into the ...
Bhabha, Gira +9 more
core +2 more sources
Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis [PDF]
, 2015 Species-specific antimicrobial therapy has the potential to combat the increasing threat of antibiotic resistance and alteration of the human microbiome.
Chen, Weihau +7 more
core +9 more sources
Antioxidants, 2022 Plastidic ferredoxin-NADP+ reductase (FNR) transfers two electrons from two ferredoxin or flavodoxin molecules to NADP+, generating NADPH. The forces holding the Anabaena FNR:NADP+ complex were analyzed by dynamic force spectroscopy, using WT FNR and ...
Sandra Pérez-Domínguez +5 more
doaj +1 more source