Mitochondrial NAD kinase in health and disease
Nicotinamide adenine dinucleotide phosphate (NADP), a co-enzyme and an electron carrier, plays crucial roles in numerous biological functions, including cellular metabolism and antioxidation.
Ren Zhang, Kezhong Zhang
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A recent study demonstrated that cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and NADP-malic enzyme (NADP-ME) have an important role in malate metabolism during fruit ripening (Osorio et al., 2013). PEPCK catalyze the ATP-dependent decarboxylation
Sonia Osorio +7 more
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Adaptation responses in C4 photosynthesis of sweet maize (Zea mays L.) exposed to nicosulfuron
Nicosulfuron is an ingredient in photosynthesis-inhibiting herbicides and has been widely used in corn post-emergence weed control. In the current study, a pair of sister lines, HK301 (nicosulfuron-tolerence, NT) and HK320 (nicosulfuron-sensitive, NS ...
Jian Wang +6 more
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Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development [PDF]
<p>Background: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized.
Sylke Müller +23 more
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Metabolic reprogramming and metabolic plasticity allow cancer cells to fine-tune their metabolism and adapt to the ever-changing environments of the metastatic cascade, for which lipid metabolism and oxidative stress are of particular importance.
Didem Ilter +11 more
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Relationships Between C4 Enzyme Activities and Yield in Soybeans (Glycine max (L.) Merr.)
To study the relationships between C4 enzyme activities and yield, C4 enzyme activities (phosphoenolpyruvate carboxylase (PEPCase), NADP-malate dehydrogenase (NADP-MDH), NADP-malic enzyme (NADP-ME), and pyruvate phosphate dikinase (PPDK)) in different ...
Shan-shan HUANG +4 more
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Biophysical characterization of the dimer and tetramer interface interactions of the human cytosolic malic enzyme. [PDF]
The cytosolic NADP(+)-dependent malic enzyme (c-NADP-ME) has a dimer-dimer quaternary structure in which the dimer interface associates more tightly than the tetramer interface. In this study, the urea-induced unfolding process of the c-NADP-ME interface
Sujithkumar Murugan, Hui-Chih Hung
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NADP-Malate Dehydrogenase of Sweet Sorghum Improves Salt Tolerance of Arabidopsis thaliana
Sweet sorghum is a C4 crop that shows high salt tolerance and high yield. NADP-malate dehydrogenase (NADP-ME) is a crucial enzyme of the C4 pathway. The regulatory mechanism of NADP-ME remains unclear.
Hongxiang Zheng (795530) +5 more
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Structural basis for the light regulation of chloroplast NADP malate dehydrogenase
The activity of chloroplast NADP-malate dehydrogenase (NADP-MDH; EC 1.1.1.82) in both C-3 and C-4 plants is regulated by light intensity, In darkness, the activity of the enzyme can be less than 1% of the maximal activity found at high light intensities.
Carr, P. D. +4 more
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Structural and kinetic characterization of NADP-dependent, non- phosphorylating glyceraldehyde-3-phosphate dehydrogenase from celery leaves [PDF]
NADP-dependent, non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.9) from celery leaves was purified over 1200-fold to a specific activity of 35 units/mg protein, and its kinetic, regulatory and structural properties were ...
Alberto A. Iglesias +5 more
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