Results 191 to 200 of about 141,947 (341)

Connecting the Dots: Bridging Microsamples and Conventional Blood Matrices in Metabolic Biomarker Analysis

open access: yesAnalytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT Bridging the gap between microsampling techniques and standard blood matrices presents a groundbreaking opportunity in metabolic biomarker analysis, offering minimally invasive, patient‐centric alternatives to traditional venipuncture. This review presents the current knowledge obtained from the comparison of biomarkers analysis in liquid ...
Marlene Thaitumu   +3 more
wiley   +1 more source

Effects of Combining Exercise and Dietary Shifts on Motor Coordination and Oxidative Markers in a High‐Fat Diet Model in Rats

open access: yesComprehensive Physiology, Volume 15, Issue 6, December 2025.
Combining exercise with a healthier diet improved weight gain, motor coordination, and antioxidant profiles in liver and muscle tissues in a high‐fat diet rat model of Metabolic Associated Fatty Liver Disease (MAFLD). These interventions restored molecular markers, highlighting coordinated tissue benefits and their potential in managing MAFLD in both ...
Manuel Jiménez‐García   +5 more
wiley   +1 more source

Characterization and evaluation of acid rain in East Central Florida from 1978 to 1987: Ten year summary report [PDF]

open access: yes
Rainfall was collected on the University of Central Florida (UCF) campus near Orlando since July 1977 and at the Kennedy Space Center (KSC), Florida since August 1977.
Dreschel, Thomas W.   +2 more
core   +1 more source

Biosynthesis and Identification of Clenbuterol Metabolites in Urine and In Vitro Microsome Incubation Samples Using UHPLC‐Q‐Exactive Orbitrap Mass Spectrometry: A Comparison Between Human and Bovine Metabolism

open access: yesDrug Testing and Analysis, Volume 17, Issue 12, Page 2314-2322, December 2025.
Clenbuterol metabolism was studied in bovine and human urine using LC‐Q‐Exactive‐Orbitrap MS; eight metabolites were identified in human and bovine samples as well as a novel N‐methylated form. Four urinary metabolites specific to cattle were detected and identified.
Anuar Gómez‐Tagle   +5 more
wiley   +1 more source

Analysis of Microbial Community Structure and Functional Genes for Volatile Flavor in Stinky Tofu

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
This study integrated metagenomics to decipher the core microbiota (e.g., Pseudomonas, Acinetobacter, Enterobacter) and functional genes governing volatile flavor biosynthesis in stinky tofu. Key enzymes like glycoside hydrolases and alcohol dehydrogenases catalyzed carbohydrate and amino acid metabolism, generating characteristic compounds such as ...
Aiguo Luo   +4 more
wiley   +1 more source

Ketogenic Nutrition in Combination With PPARα Activation Induced Metabolic Failure and Exacerbated Muscle Weakness in Septic Mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Suppression of the peroxisome proliferator‐activated receptor alpha (PPARα) has been related to poor outcomes in sepsis and may compromise ketogenesis during critical illness. Infusion of 3‐hydroxybutyrate (3HB) was shown to attenuate muscle weakness in septic mice.
Caroline Lauwers   +12 more
wiley   +1 more source

An enantioselective NADP+-dependent alcohol dehydrogenase responsible for cooxidative production of (3S)-5-hydroxy-3-methyl-pentanoic acid [PDF]

open access: bronze, 2016
Minoru Takeda   +6 more
openalex   +1 more source

circRNA‐SORE/UBQLN1/GPX4 Mediates the Acquisition of Sorafenib Resistance in Hepatocellular Carcinoma Through Inhibition of Ferroptosis

open access: yesMedComm, Volume 6, Issue 12, December 2025.
ABSTRACT The clinical performance of targeted therapies for treating hepatocellular carcinoma (HCC) is significantly limited by the frequent emergence of drug resistance, ultimately resulting in therapeutic failure and poor prognosis. While the precise mechanisms underlying this resistance are not fully elucidated.
Lin Ji   +7 more
wiley   +1 more source

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