Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase [PDF]
, 2005 Human glucose-6-phosphate dehydrogenase (G6PD) is NADP(+)-dependent and catalyses the first and rate-limiting step of the pentose phosphate shunt. Binary complexes of the human deletion mutant, DeltaG6PD, with glucose-6-phosphate and NADP(+) have been ...
Adams, MJ +5 more
core +1 more source
Biological roles of crop NADP-malic enzymes and molecular mechanisms involved in abiotic stress [PDF]
, 2013 The abiotic stress tolerance of plants is very important for plant growth, development, survival and functional performance. NADP-ME is one of the most important enzymes in plants.
Brestic, M +5 more
core +2 more sources
The NAD(P)H:flavin oxidoreductase from Escherichia coli. Evidence for a new mode of binding for reduced pyridine nucleotides [PDF]
The journal of biological chemistry, American Society for
Biochemistry and Molecular Biology, 1999, 274, pp.18252-60, 2015 The NAD(P)H:flavin oxidoreductase from Escherichia coli, named Fre, is a monomer of 26.2 kDa that catalyzes the reduction of free flavins using NADPH or NADH as electron donor. The enzyme does not contain any prosthetic group but accommodates both the reduced pyridine nucleotide and the flavin in a ternary complex prior to oxidoreduction.
arxiv +1 more source
Bio-Protocol, 2014 A recent study demonstrated that cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and NADP-malic enzyme (NADP-ME) have an important role in malate metabolism during fruit ripening (Osorio et al., 2013). PEPCK catalyze the ATP-dependent decarboxylation
Sonia Osorio +7 more
doaj +1 more source
Coding Synthetic Chemistry Strategies for Furan Valorization into Bacterial Designer Cells**
ChemSusChem, Volume 16, Issue 2, January 20, 2023., 2023 Designer cells: A microbial factory is designed to directly convert furfuryl alcohols to synthetically valuable and enantioenriched delta‐lactones. Pairing Achmatowicz ring expansions and borrowing hydrogen redoxisomerizations, two otherwise non‐natural transformations, this study highlights the potential of introducing novel biocatalytic tools into ...
Yu‐Chang Liu +2 more
wiley +1 more source
Cytosolic NADP-isocitrate dehydrogenase in Arabidopsis leaves and roots
Biologia Plantarum, 2012 NADP-dependent isocitrate dehydrogenase (NADP-ICDH) catalyses the production of NADPH, which is an essential component in the cellular homeostasis. In Arabidopsis, the kinetic parameters (K m and V max) of cytosolic NADP-ICDH were different in leaves and
M. Leterrier +3 more
doaj +1 more source
Divergent evolution of protein conformational dynamics in dihydrofolate reductase. [PDF]
, 2013 Molecular evolution is driven by mutations, which may affect the fitness of an organism and are then subject to natural selection or genetic drift. Analysis of primary protein sequences and tertiary structures has yielded valuable insights into the ...
Bhabha, Gira +9 more
core +2 more sources
Phosphoenolpyruvate Carboxykinase Is Involved in the Decarboxylation of Aspartate in the Bundle Sheath of Maize [PDF]
, 1999 We recently showed that maize (Zea mays L.) leaves contain appreciable amounts of phosphoenolpyruvate carboxykinase (PEPCK; R.P. Walker, R.M. Acheson, L.I. Técsi, R.C. Leegood [1997] Aust J Plant Physiol 24: 459–468).
Chen, Z. +3 more
core +2 more sources
A Neighbourhood-Aware Differential Privacy Mechanism for Static Word Embeddings [PDF]
arXiv, 2023 We propose a Neighbourhood-Aware Differential Privacy (NADP) mechanism considering the neighbourhood of a word in a pretrained static word embedding space to determine the minimal amount of noise required to guarantee a specified privacy level. We first construct a nearest neighbour graph over the words using their embeddings, and factorise it into a ...
arxiv
Network reconstruction of platelet metabolism identifies metabolic signature for aspirin resistance. [PDF]
, 2014 Recently there has not been a systematic, objective assessment of the metabolic capabilities of the human platelet. A manually curated, functionally tested, and validated biochemical reaction network of platelet metabolism, iAT-PLT-636, was reconstructed
Bordbar, Aarash +4 more
core +2 more sources