Results 61 to 70 of about 56,076 (155)

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Ferredoxin-ferredoxin NADP reductase interaction:catalytic differnces between the soluble and thylakoid-bound complex [PDF]

, 2015
2Ferredoxin-NADP reductase (FNR) and ferredoxin form a complex when the former is membrane-bound as they do when both components are in solution, with the same dissociation constant. The rate constant of NADP photoreduction, first order with respect to
Bracale, Marcella, Forti, Giorgio
core   +1 more source

Nanotechnology in brain cancer treatment: The role of gold nanoparticles as therapeutic enhancers

Ibrain, EarlyView.
This review highlights the potential of gold nanoparticles (AuNPs) in overcoming the blood‐brain barrier (BBB) to improve brain tumor treatment. By enabling targeted drug delivery and enhancing therapies like radiotherapy, phototherapy, and chemotherapy, AuNPs offer a promising approach for safer, more effective treatments of glioblastoma and other ...
Simona Tarantino, Annalisa Bianco, Valeria De Matteis, Edoardo Scarpa, Rosaria Rinaldi   +4 more
wiley   +1 more source

Leaves play a central role in the adaptation of nitrogen and sulfur metabolism to ammonium nutrition in oilseed rape (Brassica napus) [PDF]

, 2010
Background: The coordination between nitrogen (N) and sulfur (S) assimilation is required to suitably provide plants with organic compounds essential for their development and growth.
Coleto, Inmaculada, de la Peña, Marlon, Rodríguez-Escalante, Jon, Bejarano, Iraide, Glauser, Gaëtan, Aparicio-Tejo, Pedro M., González-Moro, M. Begoña, Marino, Daniel   +7 more
core   +5 more sources

The estrobolome: Estrogen‐metabolizing pathways of the gut microbiome and their relation to breast cancer

International Journal of Cancer, EarlyView.
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder, Amee R. Manges, Rachel A. Murphy   +2 more
wiley   +1 more source

Delineation of gastrointestinal tumors biopsies using a fluorescence lifetime imaging optical fiber probe

Journal of Biophotonics, EarlyView.
The efficient discrimination of a hepatic cancer lesion and its surgical margin using autofluorescence lifetime imaging is presented. White light image of the specimen on the left and the augmented image with fluorescence lifetime data on the right.
D. Suraci, E. Baria, L. Tirloni, J. L. Lagarto, S. Buccianti, C. Agostini, S. Pillozzi, L. Antonuzzo, A. Taddei, R. Cicchi   +9 more
wiley   +1 more source

Shining a Light on the Future of Biophotonics

Journal of Biophotonics, EarlyView.
ABSTRACT Biophotonics—the interdisciplinary fusion of light‐based technologies with biology and medicine—is rapidly transforming research, diagnostics, and therapy across various domains. This white paper, developed in conjunction with the International Congress on Biophotonics 2024, offers a comprehensive overview of the current landscape and future ...
Francesco Baldini, Kishan Dholakia, Paul French, Orlando Guntinas‐Lichius, Achim Kohler, Werner Mäntele, Laura Marcu, Ronald Sroka, Siva Umapathy, Juergen Popp   +9 more
wiley   +1 more source

Method for Accurately Assessing the Impact of Enzyme Encapsulation in a Protein Nanocage

Nano Select, EarlyView.
We have developed methods for both encapsulating a thermostable enzyme within the artificial protein nanocage TIP60 and releasing it by heating. This enables a direct comparison of the activity of confined and free enzymes under identical reaction conditions, providing a more accurate assessment of how encapsulation affects enzymatic activity ...
Norifumi Kawakami, Mao Kitamura, Keiichi Hayashi, Eri Kiyota, Ryoichi Arai, Kenji Miyamoto   +5 more
wiley   +1 more source

Manual for starch gel electrophoresis: A method for the detection of genetic variation [PDF]

, 1987
The procedure to conduct horizontal starch gel electrophoresis on enzymes is described in detail. Areas covered are (I) collection and storage of specimens, (2) preparation of tissues, (3) preparation of a starch gel, (4) application of enzyme extracts ...
Aebersold, Paul B., Milner, George B., Teel, David J., Utter, Fred M., Winans, Gary A.   +4 more
core  

Tissue‐Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency

PROTEOMICS, EarlyView.
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo, Jeremie Zander Lindeque, Marianne Venter   +2 more
wiley   +1 more source