Results 71 to 80 of about 141,947 (341)
Fermentation, 2017 Acetic acid is undesired in Icewine. It is unclear whether its production by fermenting yeast is linked to the nicotinamide adenine dinucleotide (NAD+/NADH) system or the nicotinamide adenine dinucleotide phosphate (NADP+/NADPH) system.
Fei Yang, Caitlin Heit, Debra L. Inglis
doaj +1 more source
Phytophthora infestans RxLR Effector PiAvr3b Targets NADP-Malic Enzyme to Promote Infection. [PDF]
Mol Plant PatholPiAvr3b is secreted from haustoria via a BFA‐insensitive pathway and targets host StME3 to enhance susceptibility. StME3 acts as a susceptibility factor, PiAvr3b stabilises StME3 independently of the 26S proteasome and autophagy pathways. NbME3 is essential for PiAvr3b to promote infection by P. infestans.
Gao W +6 more
europepmc +2 more sources
The Plant Journal, 2018 NADP is a key electron carrier for a broad spectrum of redox reactions, including photosynthesis. Hence, chloroplastic NADP status, as represented by redox status (ratio of NADPH to NADP+ ) and pool size (sum of NADPH and NADP+ ), is critical for ...
S. Hashida +5 more
semanticscholar +1 more source
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
MNADK, a novel liver-enriched mitochondrion-localized NAD kinase
Biology Open, 2013 Summary NADP+ and its reducing equivalent NADPH are essential for counteracting oxidative damage. Mitochondria are the major source of oxidative stress, since the majority of superoxide is generated from the mitochondrial respiratory chain. Because NADP+
Ren Zhang
doaj +1 more source
Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis [PDF]
, 2015 Species-specific antimicrobial therapy has the potential to combat the increasing threat of antibiotic resistance and alteration of the human microbiome.
Chen, Weihau +7 more
core +5 more sources
FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine
Advanced Science, EarlyView.This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang +15 more
wiley +1 more source
National Atmospheric Deposition Program 2006 Annual Summary [PDF]
, 2007 published or submitted for publicationis peer ...
National Atmospheric Deposition Program
core
CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation
Advanced Science, EarlyView.Cell proliferation requires the integration of cell cycle and anabolic signals. G1‐phase regulator CDH1 coordinates anabolism through the CDH1‐VHL‐AARS2/HIF1α axis, while CDH1‐accumulated R5P is sensed by TKTL1 to facilitate CDH1 degradation and cell cycle initiation, constituting a CDH1‐centered regulatory circuit.
Yun‐Zi Mao +18 more
wiley +1 more source
Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase [PDF]
, 2005 Human glucose-6-phosphate dehydrogenase (G6PD) is NADP(+)-dependent and catalyses the first and rate-limiting step of the pentose phosphate shunt. Binary complexes of the human deletion mutant, DeltaG6PD, with glucose-6-phosphate and NADP(+) have been ...
Adams, MJ +5 more
core +1 more source