Results 71 to 80 of about 72,905 (323)

Antagonistic Regulation by CPN60A and CLPC1 of TRXL1 that Regulates MDH Activity Leading to Plant Disease Resistance and Thermotolerance

Cell Reports, 2020
Summary: Global warming and emerging plant diseases challenge agricultural food/feed production. We identify mechanism(s) regulating both plant thermotolerance and disease resistance.
Bikram Datt Pant, Sunhee Oh, Hee-Kyung Lee, Raja Sekhar Nandety, Kirankumar S. Mysore   +4 more
doaj   +1 more source

Biochemical and molecular characterization of the isocitrate dehydrogenase with dual coenzyme specificity from the obligate methylotroph Methylobacillus Flagellatus. [PDF]

PLoS ONE, 2017
The isocitrate dehydrogenase (MfIDH) with unique double coenzyme specificity from Methylobacillus flagellatus was purified and characterized, and its gene was cloned and overexpressed in E. coli as a fused protein.
Anastasia Y Romkina, Michael Y Kiriukhin
doaj   +1 more source

Biosynthesis and Identification of Clenbuterol Metabolites in Urine and In Vitro Microsome Incubation Samples Using UHPLC‐Q‐Exactive Orbitrap Mass Spectrometry: A Comparison Between Human and Bovine Metabolism

Drug Testing and Analysis, EarlyView.
Clenbuterol metabolism was studied in bovine and human urine using LC‐Q‐Exactive‐Orbitrap MS; eight metabolites were identified in human and bovine samples as well as a novel N‐methylated form. Four urinary metabolites specific to cattle were detected and identified.
Anuar Gómez‐Tagle, Claudia Bressan, Rosa Ventura, Alan Álvarez‐Sanchez, Enrique Cardenas‐Yong, Benjamín Velasco‐Bejarano   +5 more
wiley   +1 more source

The three-dimensional structure of Clostridium absonum 7α-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition

Scientific Reports, 2016
7α-hydroxysteroid dehydrogenase (7α-HSDH) can catalyse the oxidation of C7 α-OH of the steroid nucleus in the bile acid metabolism. In the paper we determined the crystal structure of 7α-HSDH from Clostridium absonum (CA 7α-HSDH) complexed with ...
D. Lou, Bochu Wang, Jun Tan, Liancai Zhu, Xiaoxi Cen, Qingzhi Ji, Yue Wang   +6 more
semanticscholar   +1 more source

Metabolic changes during cardiac regeneration in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich, Sofie Amalie Andersson, Morten Busk, Kasper Hansen, Casper Bindzus Foldager, Johan Palmfeldt, Asger Andersen, Michael Pedersen, Mikkel Vendelbo, Kirstine Lykke Nielsen, Henrik Lauridsen   +10 more
wiley   +1 more source

Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction

Scientific Reports, 2015
Eukaryotic metabolism is organised in complex networks of enzyme catalysed reactions which are distributed over different organelles. To quantify the compartmentalised reactions, quantitative measurements of relevant physiological variables in different ...
Jinrui Zhang, A. Pierick, Harmen M. van Rossum, R. Maleki Seifar, C. Ras, J. Daran, J. Heijnen, S. Aljoscha Wahl   +7 more
semanticscholar   +1 more source

NADP-malic Enzyme OsNADP-ME2 Modulates Plant Height Involving in Gibberellin Signaling in Rice

Rice
Plants NADP-malic enzymes (NADP-MEs) act as a class of oxidative decarboxylase to mediate malic acid metabolism in organisms. Despite NADP-MEs have been demonstrated to play pivotal roles in regulating diverse biological processes, the role of NADP-MEs ...
Bing Li, Xiaolong Zhou, Wei Yao, Jinjun Lin, Xiaowen Ding, Qianru Chen, Hao Huang, Wenfeng Chen, Xilai Huang, Sujun Pan, Yinghui Xiao, Jianfeng Liu, Xionglun Liu, Jinling Liu   +13 more
doaj   +1 more source

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

International Journal of Cancer, EarlyView.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello, Eric Felli, Teresa Musarra, Lorenzo Nevi, Annamaria Altomare, Jordi Gracia‐Sancho, Andrea Baiocchini, Simone Carotti   +7 more
wiley   +1 more source

Modification of Oxidative Stress Induced by Exposure to Arsenate in Rat Chondrocytes Treated With Chitosan–Glutathione Nanoparticles

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoparticles can modify the signaling pathways related to the toxic effects of xenobiotics and their toxicity by adding compounds that alter the oxidation–reduction state, such as glutathione (GSH). This work aimed to evaluate the antioxidant capacity of chitosan–glutathione nanoparticles (NPs Q‐GSH) to modify lipoperoxidation induced by ...
Laura Denise López Barrera, Viridiana García García, Joselo Ramon Martínez Rosas, Elizabeth Soria‐Castro, Roberto Diaz Torres, Patricia Ramírez Noguera   +5 more
wiley   +1 more source

Delineation of gastrointestinal tumors biopsies using a fluorescence lifetime imaging optical fiber probe

Journal of Biophotonics, EarlyView.
The efficient discrimination of a hepatic cancer lesion and its surgical margin using autofluorescence lifetime imaging is presented. White light image of the specimen on the left and the augmented image with fluorescence lifetime data on the right.
D. Suraci, E. Baria, L. Tirloni, J. L. Lagarto, S. Buccianti, C. Agostini, S. Pillozzi, L. Antonuzzo, A. Taddei, R. Cicchi   +9 more
wiley   +1 more source