Results 81 to 90 of about 119,483 (255)

Development of a Highly Sensitive Time‐Resolved Fluorescence Immunochromatographic Assay for Rapid Onsite Determination of Prometryn Residues in Food Samples

open access: yesFood Safety and Health, EarlyView.
The recombinant full‐length antibody against prometryn (PRO‐rAb) was prepared by HEK293 (F) cell expression system and utilized as the foundation for time‐resolved fluorescence immunochromatographic assay (TRFICA). The established method showed good performance for the detection of prometryn residues in five food samples. ABSTRACT Prometryn, a triazine
Jing Zhao   +10 more
wiley   +1 more source

NADP-Dependent Isocitrate Dehydrogenase from Arabidopsis Roots Contributes in the Mechanism of Defence against the Nitro-Oxidative Stress Induced by Salinity

open access: yesThe Scientific World Journal, 2012
NADPH regeneration appears to be essential in the mechanism of plant defence against oxidative stress. Plants contain several NADPH-generating dehydrogenases including isocitrate dehydrogenase (NADP-ICDH), glucose-6-phosphate dehydrogenase (G6PDH), 6 ...
Marina Leterrier   +4 more
doaj   +1 more source

Solution Structures of \u3cem\u3eMycobacterium tuberculosis\u3c/em\u3e Thioredoxin C and Models of Intact Thioredoxin System Suggest New Approaches to Inhibitor and Drug Design [PDF]

open access: yes, 2013
Here, we report the NMR solution structures of Mycobacterium tuberculosis (M. tuberculosis) thioredoxin C in both oxidized and reduced states, with discussion of structural changes that occur in going between redox states.
Cai, Sheng   +3 more
core   +1 more source

The mechano-chemistry of cytoskeletal force generation [PDF]

open access: yes, 2014
In this communication, we propose a model to study the non-equilibrium process by which actin stress fibers develop force in contractile cells. The emphasis here is on the non-equilibrium thermodynamics, which is necessary to address the mechanics as ...
Garikipati, Krishna, Maraldi, Mirko
core   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

open access: yesiNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen   +6 more
wiley   +1 more source

The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones [PDF]

open access: yes, 2017
Vertebrate rod and cone photoreceptors require continuous supply of chromophore for regenerating their visual pigments after photoactivation. Cones, which mediate our daytime vision, demand a particularly rapid supply of 11-cis retinal chromophore in ...
Cornwall, M. Carter   +3 more
core   +2 more sources

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Cofactor Fingerprinting with STD NMR to Characterize Proteins of Unknown Function: Identification of a Rare cCMP Cofactor Preference [PDF]

open access: yes, 2004
Proteomics efforts have created a need for better strategies to functionally categorize newly discovered proteins. To this end, we have employed saturation transfer difference NMR with pools of closely related cofactors, to determine cofactor preferences.
Sem, Daniel, Yao, Huili
core   +1 more source

In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma. [PDF]

open access: yes, 2019
Dysregulation in NAD+/NADH levels is associated with increased cell division and elevated levels of reactive oxygen species in rapidly proliferating cancer cells.
Batsios, Georgios   +7 more
core   +3 more sources

Gene turnover in the common ancestor of all C4 grasses

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira   +6 more
wiley   +1 more source

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