Results 101 to 110 of about 75,190 (277)

Polydatin Alleviates APAP‐Induced Hepatotoxicity by Targeting C/EBPβ to Suppress the NLRP3 Inflammasome Signaling Pathway

iNew Medicine, EarlyView.
PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang, Chen Wang, Yi Ding, Wei‐Kang Zhang, Ling Zheng, Li Yue, Lei Zhang   +6 more
wiley   +1 more source

Enzymatic Synthesis of Caged NADP Cofactors:  Aqueous NADP Photorelease and Optical Properties

, 2016
The synthesis of caged NADP analogues 18, 19, and 20 has been accomplished by utilizing the transglycosidase activity of solubilized NAD glycohydrolase (porcine brain) to incorporate caged nicotinamides 2, 3, and 4 into NADP.
Andrew P. Patron (3049230), Charles P. Salerno (2998929), Douglas Magde (2485156)   +2 more
core   +1 more source

Dental enamel hypoplasia and intra‐tooth isotope records as indicators of physiological stress and environmental variability in Early Pleistocene hippopotamids from Melka Kunture (Upper Awash, Ethiopia)

Journal of Quaternary Science, EarlyView.
ABSTRACT Enamel hypoplasia results from temporary disruptions of enamel deposition during tooth development. It is widely used as an indicator of physiological stress in archeological and paleontological contexts; yet, its relationship with environmental conditions during tooth formation remains poorly constrained.
Giuseppe Briatico, Denis Geraads, Rita T. Melis, Margherita Mussi   +3 more
wiley   +1 more source

NADP⁺ and NADPH measure

The abundance of NADP+ and NADPH as well as the ratio of NADP+/NADPH measured by the LC-MS analysis in naïve NANOG iKO SHhES8 hESCs, either untreated or treated with DOX for three days. Data are presented as mean ± SEM (n=6)
王, 永强
core   +1 more source

National Atmospheric Deposition Program 2014 Annual Summary [PDF]

, 2015
The National Atmospheric Deposition Program (NADP) provides fundamental measurements that support informed decisions on environmental issues related to precipitation and atmospheric deposition chemistry, as well as atmospheric mercury and ammonia.

core  

Beyond a dual role: how Purpureocillium lilacinum reprograms citrus metabolism for integrated biocontrol and growth promotion

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Plants harbor complex microbial communities that are fundamental to their health and productivity. Among them, endophytic fungi such as Purpureocillium lilacinum establish mutualistic associations, offering dual benefits as plant growth promoters and biocontrol agents.
Sana Bouzembila, Kamel Charaabi, Haytham Hamden, Salma Fadhel, Nesrine Tanfouri, Meriem Msaad Guerfali   +5 more
wiley   +1 more source

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source

Time‐Resolved Effects of Cold Atmospheric Plasma on E. coli GW‐AmxH19 Transcriptome and Proteome in an Emulated Wastewater Environment

PROTEOMICS, EarlyView.
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt, Dominik Schneider, Julia Rielicke, Susanne Sievers, Veronika Hahn, Mechthild Bömeke, Anja Poehlein, Dirk Albrecht, Juergen F. Kolb, Katharina Riedel, Rolf Daniel, Daniela Zühlke   +11 more
wiley   +1 more source

National Atmospheric Deposition Program 2013 Annual summary [PDF]

, 2014
During 2013, 208 journal articles and reports were published using the NADP data.• Two new text books used NADP information during 2013: (Millard’s Probability, Statistics and Information, and Harris’ Exploring Chemical Analysis [in Chinese]) as well ...

core  

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source