Small changes in the activity of chloroplastic NADP+‐dependent ferredoxin oxidoreductase lead to impaired plant growth and restrict photosynthetic activity of transgenic tobacco plants [PDF]
Mohammad‐Reza Hajirezaei +6 more
openalex +1 more source
Insights into the catalytic mechanism of formate dehydrogenases from different microbial sources
This integrated study combines experimental enzyme kinetics with QM/MM simulations to map the catalytic mechanisms of four formate dehydrogenases at the atomic level. This approach reveals the key determinants of catalytic efficiency and guides the rational design of biocatalysts for effective CO2 reduction—a crucial step towards sustainable ...
Laura Legnani +8 more
wiley +1 more source
Crystal Packing of Protomers Provides a Valuable Structural Insight into Protein Structure
The crystal structure of proteins is generally considered static due to the constraints imposed by crystal packing. We determined the crystal structure of rice NADP-malic enzyme 2 (OsNADP-ME2), an oxidative decarboxylase that converts malic acid to ...
Dong-Hyun Lee +7 more
doaj +1 more source
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors. [PDF]
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Xu Z +9 more
europepmc +3 more sources
Expression analysis of ROS scavenging enzyme encoding genes in rubber tree infected by Microcyclus ulei [PDF]
South American Leaf Blight (SALB), caused by the ascomycete Microcyclus ulei is responsible for the low productivity of rubber tree in Latin America and represents an important threat for rubber plantations in Asia and Africa, where production is derived
Cardoso, Sandro +6 more
core
Fast & fuelious: the malate–aspartate shuttle in brown adipocyte lipid metabolism
Brown adipose tissue (BAT) produces heat in response to cold exposure, for which it relies on the coordination of aerobic and anaerobic metabolism. However, how reaction intermediates connect these two essential pathways is unclear. In this issue of The FEBS Journal, Veliova et al., report that the malate–aspartate shuttle (MAS) supports norepinephrine‐
Lukas Blaas, Alexander Bartelt
wiley +1 more source
The multidimensional regulation roles and mechanisms of calcium in fruit quality
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang +6 more
wiley +1 more source
Characterization and transcriptional regulation of the Synechocystis PCC 6803, petH gene, encoding ferredoxin-NADP+ oxidoreductase: involvement of a novel type of divergent operator [PDF]
Jasper J. van Thor +2 more
openalex +1 more source
Genomic variation drives plant flavor diversification
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu +5 more
wiley +1 more source

