Results 131 to 140 of about 62,836 (259)

USP43‐mediated deubiquitination of SLC7A11 protects against LPS‐induced acute lung injury by inhibiting ferroptosis

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Ubiquitin‐specific protease 43 (USP43) in up‐regulated during lipopolysaccharide (LPS)‐induced acute lung injury (ALI). USP43 interacts and inhibits the degradation of solute carrier family 7 member 11 (SLC7A11) by removing the K48‐linked ubiquitination of it, thereby suppressing ferroptosis.
Li Zhang, Jutong He, Ming Xu, Bamawa Mwengendi Joël, Guiomar Correia, Xuefeng Zhou, Xinyi Li, Hexiao Tang   +7 more
wiley   +1 more source

Cofactor Engineering Strategy of Food-Grade Microorganisms: Redox Homeostasis Regulation and Functional Components Biofortification. [PDF]

Microorganisms
Zhang D, Wang H, Song X, Xia Y, Wang G, Xiong Z, Ai L.   +6 more
europepmc   +1 more source

An interpretable multi‐task whole‐slide histopathology AI model for non‐small cell lung cancer: Cross‐cohort generalisation, spatial attention–transcriptomic integration, and molecular–immune profiling

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
SparseAGE‐MTL analyses routine haematoxylin and eosin pathology images from multicentre non‐small cell lung cancer cohorts to generate subtype‐classification, stage‐probability and survival‐risk outputs. Task‐specific attention maps and risk scores were integrated with spatial and bulk transcriptomics, linking high‐attention regions and high‐risk cases
Renyi Lu, Anqi Lin, Aimin Jiang, Yuying Feng, Xiuhui Fang, Junyi Shen, Yifeng Bai, Shengkun Peng, Jian Zhang, Quan Cheng, Suyin Feng, Qinglin Li, Peng Luo   +12 more
wiley   +1 more source

<i>MeNADP-ME3</i> Confers Salt and Drought Tolerance in <i>Arabidopsis</i> and Drives Functional Diversification of the <i>NADP-ME</i> Family in Cassava. [PDF]

Curr Issues Mol Biol
Wu S, Xia Z, Zhao J, Wang C, Min Y, Wang D.   +5 more
europepmc   +1 more source

A Novel Workflow for Fast Elucidation of Drug Metabolites for Screening—Combining In Silico Metabolite Prediction With Trapped Ion Mobility QTOF‐MS

Drug Testing and Analysis, Volume 18, Issue 7, Page 841-851, July 2026.
UHPLC‐timsTOF‐MS with in silico prediction and automated annotation enabled rapid identification of quetiapine metabolites from pHLMs, facilitating their inclusion in targeted LC‐QTOF‐MS urine screening and improving biomarker detection for toxicological applications.
Annette Zschiesche, Birgit Schneider, Ilona Nordhorn, Carsten Baessmann, Laura M. Huppertz, Jürgen Kempf   +5 more
wiley   +1 more source

Proximity-enhanced co-immobilized enzyme cascade for efficient bioconversion of nicotine to 3-succinoylpyridine. [PDF]

Bioresour Bioprocess
Wang Y, Zhang J, Yang H, Wei J, Song K, Li S, Shen L, Yang G, Ali MY, Wang Z, Zhang Y, Wang Y.   +11 more
europepmc   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

ADH4 deficiency activates the NRF2-CSF1 axis by increased lipid peroxidation in hepatocellular carcinoma. [PDF]

Cancer Cell Int
Yan P, Luo Y, Peng D, Mou T, Lei D, Li S, Yu H, Huang Z, Wu Z.   +8 more
europepmc   +1 more source

Curcumin Attenuates Aroclor 1254‐Induced Oxidative, Genotoxic, and Apoptotic Alterations in HepG2 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
In HepG2 cells, Aroclor 1254 induced oxidative stress, DNA damage, apoptosis, and mutagenicity; co‐treatment with curcumin restored antioxidant defenses (GSH/thiols; SOD, CAT, GPx, GR, TrxR), reduced ROS and comet/8‐OHdG readouts, and attenuated caspase activation, demonstrating curcumin's hepatoprotective and genoprotective modulation of PCB toxicity.
Pınar Erkekoğlu, Selinay Başak Erdemli Köse, Hülya Tezel Yalçın, Deniz Arca Çakır   +3 more
wiley   +1 more source

Antisense reduction in NADP-ME in the C₄ species Flaveria bidentis alters stomatal sensitivity to intercellular [CO₂]. [PDF]

New Phytol
Bernardo EL, Sales CRG, Sun T, Kromdijk J.   +3 more
europepmc   +1 more source