Results 111 to 120 of about 125,071 (335)

AKR1C3 Binds β‐Trcp to Promote the Degradation of TFRC to Protect Hepatocellular Carcinoma From Ferroptosis

open access: yesCancer Science, EarlyView.
In this study, we show that aldo‐keto reductase family 1 member C3 (AKR1C3), a protein highly expressed in ferroptosis resistant hepatocellular carcinoma cells, acts as an enzyme‐independent scaffold protein by promoting the nuclear export of β‐transducin repeat protein (β‐TrCP) and its binding to transferrin receptor (TFRC) in an enzyme‐independent ...
Lei Qi   +10 more
wiley   +1 more source

Salinity Induces Granal Development in Bundle Sheath Chloroplasts of NADP-Malic Enzyme Type C4 Plants

open access: yesPlant Production Science, 2009
In NADP-malic enzyme (NADP-ME) type C4 plants, MC chloroplasts have well-developed grana, whereas BSC chloroplasts are generally characterized by highly reduced grana.
Eiji Omoto   +3 more
doaj   +1 more source

Identification of the NADP+ Structural Binding Site and Coenzyme Effect on the Fused G6PD::6PGL Protein from Giardia lamblia

open access: yesBiomolecules, 2019
Giardia lambia is a flagellated protozoan parasite that lives in the small intestine and is the causal agent of giardiasis. It has been reported that G. lamblia exhibits glucose-6-phosphate dehydrogenase (G6PD), the first enzyme in the pentose phosphate ...
Laura Morales-Luna   +17 more
doaj   +1 more source

Manual for starch gel electrophoresis: A method for the detection of genetic variation [PDF]

open access: yes, 1987
The procedure to conduct horizontal starch gel electrophoresis on enzymes is described in detail. Areas covered are (I) collection and storage of specimens, (2) preparation of tissues, (3) preparation of a starch gel, (4) application of enzyme extracts ...
Aebersold, Paul B.   +4 more
core  

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

open access: yesThe FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito   +8 more
wiley   +1 more source

Aluminium effects on pyridine nucleotide redox state in roots of Scots pine

open access: yesActa Societatis Botanicorum Poloniae, 2014
After prolonged (3-9 weeks) hydroponic treatment of Scots pine seedlings with different concentrations (0.5-4.0 mM) of Al (AI(N03)3), the levels of pyridine nucleotides were determined in root homogenates.
Gabriela Lorenc-Plucińska   +1 more
doaj   +1 more source

Characterisation of components and mechanisms involved in redox-regulation of protein import into chloroplasts [PDF]

open access: yes, 2009
The vast majority of chloroplast proteins is encoded in the nucleus and thus has to be posttranslationally imported into the organelle, a process that is facilitated by two multimeric protein machineries, the Toc and Tic complexes (translocon at the ...
Stengel, Anna
core  

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

open access: yesThe FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo   +4 more
wiley   +1 more source

Sources of reducing equivalents for nitrite reductase in Pisum arvense roots

open access: yesActa Societatis Botanicorum Poloniae, 2014
Glucose-6-phosphate and NADP+ as well as malic acid and NADP+ present in the incubation mixture enhanced nitrite reductase (EC 1.6.6.4) activity in Pisum arvense roots.
Grażyna Kłobus
doaj   +1 more source

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