Defining Rational Photoelectron Routing for Targeted Intracellular Energy Transfer. [PDF]
Wang H +8 more
europepmc +1 more source
SUMMARY An unbiased, quantitative view of biomolecules in a living cell is a prerequisite for accurate modeling approaches and informs our understanding of cellular metabolism at scale. In this work, we used the total protein approach (TPA), in which the total protein mass of a given proteomics sample is used as a calibrator for absolute protein ...
Stefan Schmollinger +6 more
wiley +1 more source
Structural and Functional Impact of the G340S Mutation in Plasmodium falciparum Ferredoxin NADP⁺ Reductase: In silico Analysis and Molecular Docking. [PDF]
Kiboi D, Muriithi B.
europepmc +1 more source
Assessing the therapeutic potential of PDE‐5 inhibitors in adults: Insights from a multi‐omics study
Abstract Phosphodiesterase‐5 inhibitors have beneficial pleiotropic effects and hold promise as adjuvant treatments for cancer, dementia, and other disorders. Sixteen men and women aged 50–60 were administered daily sildenafil/tadalafil for 1 month. We characterized molecular signatures of sildenafil/tadalafil treatment via analyses and multi‐omics ...
Kristen A. McGovern +14 more
wiley +1 more source
Smoke-Affected Rain Fertilizes Terrestrial and Aquatic Ecosystems. [PDF]
Ponette-González AG +4 more
europepmc +1 more source
ω‐Hydroxy and ω‐oxo acids are precursors to lactones, polyesters, and nylon‐6, yet selective interconverting enzymes remain scarce. Clostridium viride supplies two iron alcohol dehydrogenases: Cvir‐Hbd2, restricted to C4, and the genomic singleton Cvir‐Hvd, spanning C5–C12 substrates.
Tarik Begic +7 more
wiley +1 more source
Sevoflurane Alleviates Myocardial Ischemia-Reperfusion Injury via the HMGB1/ACSL4 Pathway to Suppress Ferroptosis. [PDF]
Mei Y, Cao Y, Sheng C, Sun G, Zhu M.
europepmc +1 more source
Employing AC and DC Electrolysis to Modulate Electroenzymatic Pathways for Efficient and Stereoselective H-D Exchange. [PDF]
El Housseini W +11 more
europepmc +1 more source
Thermodynamic metabolic modeling of growth and bioproduction potential of the acetogen <i>Acetobacterium woodii</i> with and without redox cofactor swaps. [PDF]
Bauer J, von Kamp A, Pflügl S, Klamt S.
europepmc +1 more source
A Structure-guided Active Site Affinity Ligand Unmasks a Stress-Sensitizing Role for BLVRB in the Endoplasmic Reticulum. [PDF]
Thekke Veedu RR +8 more
europepmc +1 more source

