Evolutionary insights into bilin biosynthesis: Functional characterization of pre‐PcyA enzymes
Protein Science, Volume 35, Issue 9, September 2026.Abstract Biosynthesis of the linear tetrapyrrole phycocyanobilin (PCB) by the ferredoxin‐dependent bilin reductase (FDBR) PcyA is essential for light‐harvesting and regulatory processes in diverse photosynthetic organisms, yet its evolutionary origins are not fully understood. PcyA evolved from pre‐PcyA proteins found in diverse bacteria.
Federica Frascogna +3 more
wiley +1 more source
Protein Science, Volume 35, Issue 9, September 2026.Abstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Isaac A. Paddy +7 more
wiley +1 more source
Dynamics of blood NAD and glutathione in health, disease, aging, and under NAD<sup>+</sup>-booster treatment. [PDF]
Redox BiolEuro L +5 more
europepmc +1 more source
Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1610-1627, September 2026.ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi +12 more
wiley +1 more source
NOX2/NOX4-associated oxidative stress contributes to G6PD-associated metabolic remodeling and ferroptosis during mice luteolysis. [PDF]
Redox RepLi F +7 more
europepmc +1 more source
Genetic analyses of leaf traits in an interspecific Zoysia japonica × Zoysia matrella F2 population
The Plant Genome, Volume 19, Issue 3, September 2026.Abstract Zoysiagrass (Zoysia spp.) is an important warm‐season turfgrass cultivated across tropical, subtropical, and temperate regions of the world. The genus is characterized by the presence of salt‐secreting glands on the adaxial leaf surface, which contribute to its high salt tolerance.
Shreena Pradhan +5 more
wiley +1 more source
Metabolic imaging for gamete and embryo assessment through advanced microscopy technologies: a novel avenue for artificial intelligence? [PDF]
Hum ReprodHorta F +8 more
europepmc +1 more source
Volatile Organic Compounds in Rainwater: A New Frontier in Atmosphere–Biosphere Interactions
Journal of Geophysical Research: Biogeosciences, Volume 131, Issue 9, September 2026.Abstract Rainwater is a key vector of atmospheric deposition, linking the atmosphere with terrestrial and aquatic ecosystems. While the inorganic chemistry of precipitation (dominated by sulfate, nitrate, ammonium, and trace metals) has been extensively studied, organic compounds in rainwater have received less attention, and Volatile Organic Compounds
Ana M. Yáñez‐Serrano +6 more
wiley +1 more source
Malic enzyme 1 senses L-lactate to determine tumor heterogeneity. [PDF]
Signal Transduct Target TherCao SY +14 more
europepmc +1 more source
Methaemoglobinaemia: From pathophysiology to contemporary clinical management
British Journal of Haematology, Volume 209, Issue 3, Page 900-910, September 2026.Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley +1 more source