Results 191 to 200 of about 56,952 (277)

Employing AC and DC Electrolysis to Modulate Electroenzymatic Pathways for Efficient and Stereoselective H-D Exchange. [PDF]

J Am Chem Soc
El Housseini W, Gerulskis R, Behera N, Guan H, Jadhav RG, Nguyen ZA, Baiarashov E, Pence MA, Kamaja VK, Larkin T, Luo L, Minteer SD.   +11 more
europepmc   +1 more source

The three-dimensional structure of Clostridium absonum 7α-hydroxysteroid dehydrogenase: new insights into the conserved arginines for NADP(H) recognition. [PDF]

Sci Rep, 2016
Lou D, Wang B, Tan J, Zhu L, Cen X, Ji Q, Wang Y.   +6 more
europepmc   +1 more source

Inverse Association Between Dietary Niacin Intake and Prevalence of Depressive Symptoms in Adults With Metabolic‐Associated Fatty Liver Disease: A Cross‐Sectional Study

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This cross‐sectional study included adults with MAFLD. Logistic regression and smooth curve fitting were used to evaluate the association between dietary and supplemental niacin intake (mg/day) and depression (PHQ‐9 score ≥ 10). The results indicate that moderate niacin intake may reduce the risk of depression in individuals with MAFLD, with a ...
Xiaoxian Yang, Haiyi Yan, Xueying Qin, Yan Chen   +3 more
wiley   +1 more source

Thermodynamic metabolic modeling of growth and bioproduction potential of the acetogen <i>Acetobacterium woodii</i> with and without redox cofactor swaps. [PDF]

Synth Syst Biotechnol
Bauer J, von Kamp A, Pflügl S, Klamt S.
europepmc   +1 more source

Evolutionary divergence of nocturnin led to redox regulation in mammalian orthologs. [PDF]

Biochem Biophys Rep
Olivas-Rasmussen CA, Gao P, Rasmussen ES, Green CB.   +3 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Collateral lethality of NAD kinase in 1p36 deleted tumors drives vulnerability to NAD kinase 2 depletion. [PDF]

BBA Adv
Suyama-Banjo S, Watanabe K, Ishikawa H, Yoshihama Y, Hirota Y, Tsutsumi S.   +5 more
europepmc   +1 more source

Metabolic Reprogramming and Exosome Remodeling in an Ndufs4‐Deficient Model of Leigh Syndrome

iNew Medicine, Volume 2, Issue 2, June 2026.
Ndufs4 knockout drives exosomal remodeling, reprograms cellular metabolism, impairs neural stem cell self‐renewal and differentiation, and suppresses mTOR signaling, providing a conceptual framework for understanding Leigh syndrome pathogenesis and informing therapeutic development.
Yakun Liu, Zhi Yang, Zhencai Xing, Rongrong Zhao, Yixuan Zhou, Xue Yang, Jicheng Zhu, Shuo Chen, Yuhang Zhang, Mengxue Xu, Xiang Kong, Minqiong Sun, Zhenya Tan, Hong Zheng   +13 more
wiley   +1 more source

Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen, Jennifer Hosmer, Saurab Kishore Munshi, Riya Joshi, Ayaho Yamamoto, Horst J. Schirra, Peter Sly, Alastair G. McEwan, Ulrike Kappler   +8 more
wiley   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang, Qitai Chen, YuJie Yu, Yi Zang, Rujia Zheng, Zhe Zhang, Shuaijun Lu, Li Zhou   +7 more
wiley   +1 more source