Densities of NADPH-ferrihemoprotein reductase and cytochrome P-450 molecules in the endoplasmic reticulum membrane of rat hepatocytes. [PDF]
Journal of Histochemistry & Cytochemistry, 1993 In hepatocytes, NADPH-ferrihemoprotein reductase (reductase) has been hypothesized to exist as aggregates or micelles in endoplasmic reticulum (ER) membrane. However, if the number of reductase molecules per unit area of ER is low, this hypothesis cannot explain how a few reductase molecules efficiently reduce many P-450 molecules.
J, Watanabe +3 more
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Measurement of NADPH-ferrihemoprotein reductase content in sections of liver. [PDF]
Journal of Histochemistry & Cytochemistry, 1991 We developed a method for measuring the content of NADPH-ferrihemoprotein reductase in sections of liver. First, reductase in sections of rat liver was detected with the indirect immunoperoxidase reaction. Subsequently, specific absorbances were measured in the stained sections by microphotometry.
J, Watanabe, K, Kanai, S, Kanamura
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A novel TetR family transcriptional regulator, SAV576, negatively controls avermectin biosynthesis in Streptomyces avermitilis. [PDF]
PLoS ONE, 2013 Avermectins produced by Streptomyces avermitilis are potent anti-parasitic agents that are useful in animal health care, agriculture, and the treatment of human infections. In a search for novel regulators that affect avermectin biosynthesis, comparative
Jia Guo +6 more
doaj +1 more source
PLoS ONE, 2014 Streptomyces avermitilis is an important bacterial species used for industrial production of avermectins, a family of broad-spectrum anthelmintic agents.
Jia Guo +4 more
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Tryptophan extends the life of cytochrome P450. [PDF]
Proc Natl Acad Sci U S A, 2023 Ravanfar R +3 more
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The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus. [PDF]
Antimicrob Agents Chemother, 2023 Kühbacher A +5 more
europepmc +1 more source
A Novel, Highly Potent NADPH-Dependent Cytochrome P450 Reductase from Waste Liza klunzingeri Liver. [PDF]
Mar Drugs, 2023 Bahramian Nasab S +4 more
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Tryptophan-96 in cytochrome P450 BM3 plays a key role in enzyme survival. [PDF]
FEBS Lett, 2023 Ravanfar R +3 more
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On 'Evidence for the participation of cytochrome b5 in hepatic microsomal mixed-function oxidation reactions' by Alfred Hildebrandt and Ronald W. Estabrook. [PDF]
Arch Biochem Biophys, 2022 Guengerich FP.
europepmc +1 more source