Results 111 to 120 of about 180,191 (302)

ResearchConnect: An AI‐Powered Platform for Interdisciplinary Research Team Formation and Ideation Development

open access: yesAdvanced Intelligent Systems, EarlyView.
ResearchConnect is an AI‐powered platform that automates researcher profiling, interdisciplinary team formation, and early‐stage research ideation. By extracting keywords from papers and web sources, it quickly clusters researchers into coherent teams and generates collaborative ideas using large language models. Validation on NSF‐funded projects shows
Akshay Vilas Jadhav   +2 more
wiley   +1 more source

α-Lipoic Acid Inhibits Helicobacter pylori-Induced Oncogene Expression and Hyperproliferation by Suppressing the Activation of NADPH Oxidase in Gastric Epithelial Cells

open access: yesMediators of Inflammation, 2014
Hyperproliferation and oncogene expression are observed in the mucosa of Helicobacter pylori- (H. pylori-) infected patients with gastritis or adenocarcinoma. Expression of oncogenes such as β-catenin and c-myc is related to oxidative stress.
Eunyoung Byun   +3 more
doaj   +1 more source

Attenuation of NADPH Oxidase Activation and Glomerular Filtration Barrier Remodeling With Statin Treatment [PDF]

open access: yes, 2008
Activation of reduced nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase by angiotensin II is integral to the formation of oxidative stress in the vasculature and the kidney.
Andresen, Bradley T.   +10 more
core   +1 more source

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew   +8 more
wiley   +1 more source

Role of NADPH Oxidase in the Endothelial Dysfunction and Oxidative Stress in Aorta of Aged Spontaneous Hypertensive Rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2010
Objective(s)Increased reactive oxygen species (ROS) production is implicated in the pathogenesis of arterial hypertension and the development of endothelial dysfunction.
Ashraf Taye, Sven Wind
doaj  

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

open access: yesAdvanced NanoBiomed Research, EarlyView.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus   +5 more
wiley   +1 more source

NADPH Oxidase 4 [PDF]

open access: yesCirculation Research, 2009
Over the last decade, the NADPH oxidases have been recognized as an important source of reactive oxygen species (ROS) involved in both normal physiologic redox-dependent processes, and in the generation of oxidative stress, with a role in the development of cardiovascular disease.
openaire   +2 more sources

NADPH oxidases: Current aspects and tools

open access: yesRedox Biology, 2020
Reactive oxygen species (ROS) have been shown or at least suggested to play an essential role for cellular signaling as second messengers. NADPH oxidases represent a source of controlled ROS formation. Accordingly, understanding the role of individual NADPH oxidases bears potential to interfere with intracellular signaling cascades without disturbing ...
openaire   +5 more sources

The free fatty acid 2 receptor regulates C5a induced neutrophil superoxide production and its sensitivity to inhibition by the antagonist avacopan

open access: yesFrontiers in Immunology
IntroductionReceptor transactivation is a novel signaling mechanism used by several different neutrophil G protein-coupled receptors (GPCRs) to activate an allosterically modulated receptor that recognizes short chain free fatty acids.
Zahra Khan   +8 more
doaj   +1 more source

A Role for Reactive Oxygen Species Produced by NADPH Oxidases in the Embryo and Aleurone Cells in Barley Seed Germination.

open access: yesPLoS ONE, 2015
Reactive oxygen species (ROS) promote the germination of several seeds, and antioxidants suppress it. However, questions remain regarding the role and production mechanism of ROS in seed germination. Here, we focused on NADPH oxidases, which produce ROS.
Yushi Ishibashi   +8 more
doaj   +1 more source

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