Results 131 to 140 of about 95,947 (261)

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

open access: yesSensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa   +5 more
wiley   +1 more source

Immunomodulatory Nanozymes as Programmable Redox–Immune Set‐Point Regulators

open access: yesSmall, EarlyView.
Conceptual phase space linking reactive oxygen species level/dynamics to immune state, with pathological set‐points for chronic inflammation, tumor escape, and degeneration contrasted against a central healthy redox–immune set‐point. Buffering and amplifying nanozymes are depicted as devices that dial redox tone up or down to steer diseased ...
Sumi Choi   +3 more
wiley   +1 more source

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior   +10 more
wiley   +1 more source

NADPH Oxidase 1 Mediates Endothelial Dysfunction and Hypertension in a Murine Model of Obesity. [PDF]

open access: yesAntioxidants (Basel)
Padgett CA   +5 more
europepmc   +1 more source

Beyond Removal Efficiency: Environmental Risk Assessment of Tartrazine Degradation via ZnO and TiO2 Nanoparticles in Mussels

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Tartrazine (TZ) is a widely used synthetic azo dye with high aqueous stability, resulting in persistence in wastewater. Photoreactive nanomaterials, principally zinc oxide (ZnO) and titanium dioxide (TiO2) nanoparticles (NPs), are frequently employed for dye removal under light‐exposed conditions; nevertheless, their ecotoxicological ...
İrem Can   +3 more
wiley   +1 more source

Influence of Age and Exposure Pathway on Copper and Cadmium Mixture Toxicity: A Study on Daphnia magna

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Metal contamination in aquatic ecosystems poses substantial risks to freshwater organisms, with mixture effects often deviating from predictions based on single‐metal toxicity. Understanding how age‐specific sensitivities and multiple exposure pathways influence mixture effects is critical for accurate risk assessment.
Sanah Majid   +3 more
wiley   +1 more source

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