Results 141 to 150 of about 95,947 (261)

Investigation of the Protective Effect of Morin on Oxidative Stress and Apoptosis in Malathion‐Induced Hepatotoxicity in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Malathion (MAL) is a widely used organophosphate pesticide associated with hepatotoxicity through oxidative stress and apoptosis. Morin, a naturally occurring flavonoid, exhibits potent antioxidant and anti‐inflammatory properties. This study investigated oxidative stress, inflammatory, and apoptotic alterations induced by acute and subacute ...
Seval Yılmaz, Eda İ. Demirbağ, Hakan Bağ, Ali O. Çeribaşı   +3 more
wiley   +1 more source

NADPH oxidase 2 inhibitor GSK2795039 exerts antiplatelet and antithrombotic activity. [PDF]

Sci Rep
Oh EB, Kong YJ, Kim T, Jang J, Yu H, Park JW, Kim S, Kim T, Sohn J, Chang TS.   +9 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Ice-Cold Temperature Enhances NADPH Oxidase-Dependent Release of Tissue Factor-Bearing Extracellular Vesicles from Human Monocytic Cells. [PDF]

Life (Basel)
Nishioka A, Azma T, Mieda T, Mio Y.
europepmc   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source

Synaptic rescue in an Alzheimer's mouse model: low-temperature steam-derived black ginseng oligosaccharides remodel protein S-nitrosylation-NADPH oxidase axis. [PDF]

NPJ Sci Food
Yu P, Liu J, Xu W, Peng L, Li Y, Shao S, Wang Y, Qiu Z, Yang H.   +8 more
europepmc   +1 more source

YK‐4‐250, a synthetic telmisartan–tempol conjugate: crystal structure of a stabilized free radical containing an angiotensin AT1 receptor inhibitor

Acta Crystallographica Section C, EarlyView.
The first crystal structure of the telmisartan–tempol conjugate YK‐4‐250 is reported, revealing the intramolecular C–H…π interactions that stabilize the nitroxide radical while preserving the angiotensin AT1 receptor antagonist pharmacophore.We report the first crystal structure of the telmisartan–tempol conjugate 2,2,6,6‐tetramethyl‐1‐(λ′‐oxidaneyl ...
Simon Friedrich, Yali Kong, Faik N. Musayev, Milton L. Brown, B. Frank Gupton   +4 more
wiley   +1 more source

NADPH Oxidases in Innate Immunity [PDF]

Journal of Innate Immunity, 2009
openaire   +2 more sources

The Role of NADPH Oxidase 2 in Leukocytes. [PDF]

Antioxidants (Basel)
Leiding JW, Mathews CE, Arnold DE, Chen J.   +3 more
europepmc   +1 more source

Mycobacterium intracellulare M.i.198—A Promising Strain for Studying Pathogenesis of Nontuberculous Mycobacterial Pulmonary Disease (NTM‐PD)

Microbiology and Immunology, EarlyView.
ABSTRACT In this review, we introduce a promising strain for studying pathogenesis of nontuberculous mycobacterial pulmonary disease (NTM‐PD), Mycobacterium intracellulare M.i.198. M.i.198 was isolated from a patient with progressive Mycobacterium avium‐intracellulare complex pulmonary disease (MAC‐PD) in whom surgical operation was required to ...
Yoshitaka Tateishi, Ryoji Maekura, Yukiko Nishiuchi, Sohkichi Matsumoto   +3 more
wiley   +1 more source