Results 71 to 80 of about 399,078 (208)
Role of NADPH Oxidase in the Endothelial Dysfunction and Oxidative Stress in Aorta of Aged Spontaneous Hypertensive Rats [PDF]
Iranian Journal of Basic Medical Sciences, 2010 Objective(s)Increased reactive oxygen species (ROS) production is implicated in the pathogenesis of arterial hypertension and the development of endothelial dysfunction.
Ashraf Taye, Sven Wind
doaj
NADPH oxidase in human lung fibroblasts
Journal of Biomedical Science, 2004 Reactive oxygen species produced by NADPH oxidase appear to play a role in the response of human lung fibroblast cells to rhinovirus infection. The purpose of the following studies was to characterize the NADPH oxidase components in these cells, to examine the effect of rhinovirus challenge on the expression of these proteins, and to confirm previous ...
Gursev S, Dhaunsi +3 more
openaire +2 more sources
Frontiers in ImmunologyIntroductionReceptor transactivation is a novel signaling mechanism used by several different neutrophil G protein-coupled receptors (GPCRs) to activate an allosterically modulated receptor that recognizes short chain free fatty acids.
Zahra Khan +8 more
doaj +1 more source
Circulation Journal, 2014 Reactive oxygen species (ROS) are the main facilitators of cardiovascular complications in diabetes mellitus (DM), and the ROS level is increased in cultured cells exposed to high glucose concentrations or in diabetic animal models.
Y. Teshima +9 more
semanticscholar +1 more source
Regulation of NADPH Oxidases [PDF]
Circulation Research, 2006 The role for reactive oxygen species (ROS) in cellular (patho)physiology, in particular in signal transduction, is increasingly recognized. The family of NADPH oxidases (NOXes) plays an important role in the production of ROS in response to receptor agonists such as growth factors or inflammatory cytokines that signal through the Rho-like ...
openaire +2 more sources
PLoS ONE, 2015 Reactive oxygen species (ROS) promote the germination of several seeds, and antioxidants suppress it. However, questions remain regarding the role and production mechanism of ROS in seed germination. Here, we focused on NADPH oxidases, which produce ROS.
Yushi Ishibashi +8 more
doaj +1 more source
Journal of Immunology, 2014 Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as a leading contributor to mortality during recent influenza pandemics. The mechanism for this influenza-induced susceptibility to secondary S. aureus infection is poorly understood. In this
Keer Sun, D. Metzger
semanticscholar +1 more source
NADPH oxidase 4 (NOX4) as a biomarker and therapeutic target in neurodegenerative diseases
Neural Regeneration ResearchDiseases like Alzheimer's and Parkinson's diseases are defined by inflammation and the damage neurons undergo due to oxidative stress. A primary reactive oxygen species contributor in the central nervous system, NADPH oxidase 4, is viewed as a potential ...
Napissara Boonpraman, Sun Shin Yi
doaj +1 more source
NADPH Oxidase-4 Mediates Myofibroblast Activation and Fibrogenic Responses to Lung Injury
Nature Medicine, 2009 Members of the NADPH oxidase (NOX) family of enzymes, which catalyze the reduction of O2 to reactive oxygen species, have increased in number during eukaryotic evolution.
L. Hecker +8 more
semanticscholar +1 more source
Journal of Neurochemistry, 2014 NADPH oxidases are important for neuronal function but detailed subcellular localization studies have not been performed. Here, we provide the first evidence for the presence of functional NADPH oxidase 2 (NOX2)‐type complex in neuronal growth cones and ...
Vidhya Munnamalai +6 more
semanticscholar +1 more source