Results 81 to 90 of about 424,484 (404)
β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase [PDF]
, 2004 β-Amyloid (βA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms of neurotoxicity remain controversial. This study establishes a central role for oxidative stress by the activation of NADPH oxidase
Abramov, A.Y. +2 more
core
p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels. [PDF]
, 2016 BACKGROUND: The NADPH oxidase, by generating reactive oxygen species, is involved in the pathophysiology of many cardiovascular diseases and represents a therapeutic target for the development of novel drugs.
Brooks, G +6 more
core +1 more source
Clarity on the Isoform-Specific Roles of NADPH Oxidases and NADPH Oxidase-4 in Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016 Atherosclerosis is a complex disease that remains a leading cause of death and disability. The formation of vascular plaques arises from the interaction of dyslipidemia with the altered function of blood vessels and immune cells. The exact cause of atherosclerosis is not known, but from the 1950s onward, oxidative modifications of lipids and proteins ...
David Fulton, Scott A. Barman
openaire +3 more sources
Advanced Synthesis &Catalysis, EarlyView.Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos +5 more
wiley +1 more source
Molecules, 2023 Disruption of apoptosis leads to cancer cell progression; thus, anticancer agents target apoptosis of cancer cells. Reactive oxygen species (ROS) induce apoptosis by activating caspases and caspase-dependent DNase, leading to DNA fragmentation.
Ju Won Eom, Joo Weon Lim, Hyeyoung Kim
doaj +1 more source
Reaction of the desulfoferrodoxin from Desulfoarculus baarsii with superoxide anion. Evidence for a superoxide reductase activity [PDF]
The journal of biological chemistry, American Society for
Biochemistry and Molecular Biology, 2000, 275, pp.115-21, 2014 Desulfoferrodoxin is a small protein found in sulfate-reducing bacteria that contains two independent mononuclear iron centers, one ferric and one ferrous. Expression of desulfoferrodoxin from Desulfoarculus baarsii has been reported to functionally complement a superoxide dismutase deficient Escherichia coli strain.
arxiv +1 more source
Small, 2015 The purpose of this paper is to elucidate the key role of NADPH oxidase in NLRP3 inflammasome activation and generation of pulmonary fibrosis by multi-walled carbon nanotubes (MWCNTs).
Bingbing Sun +9 more
semanticscholar +1 more source
The Arabidopsis NADPH oxidases RbohD and RbohF display differential expression patterns and contributions during plant immunity [PDF]
, 2016 Plant NADPH oxidases, also known as respiratory burst oxidase homologues (RBOHs), produce reactive oxygen species (ROS) that perform a wide range of functions.
Antonio Molina +6 more
core +1 more source
A 3D‐Printed Microfluidic Sensor Platform for Online Bioprocess Monitoring
Advanced Sensor Research, EarlyView.A 3D‐printed microfluidic lab‐on‐a‐chip sensor platform is presented, compatible with various cultivation setups, that integrates sensors for pH, pO₂, pCO₂, glucose, lactate, and additionally features a sampling unit for small‐volume abstraction. With this platform, continuous real‐time monitoring of critical bioprocess parameters is enabled and ...
Christopher Heuer +5 more
wiley +1 more source
NADPH Oxidase Activation Contributes to Heavy Ion Irradiation–Induced Cell Death
Dose-Response, 2017 Increased oxidative stress plays an important role in heavy ion radiation–induced cell death. The mechanism involved in the generation of elevated reactive oxygen species (ROS) is not fully illustrated.
Yupei Wang +6 more
doaj +1 more source