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NADPH Oxidases in Aortic Aneurysms [PDF]
Abdominal aortic aneurysms (AAAs) are a progressive dilation of the infrarenal aorta and are characterized by inflammatory cell infiltration, smooth muscle cell migration and proliferation, and degradation of the extracellular matrix.
Morgan Salmon
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NADPH Oxidases in Pain Processing [PDF]
Inflammation or injury to the somatosensory nervous system may result in chronic pain conditions, which affect millions of people and often cause major health problems.
Wiebke Kallenborn-Gerhardt+2 more
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NADPH Oxidases and Their Role in Atherosclerosis [PDF]
The current view on atherosclerosis positions it as a multifactorial disorder that results from the interplay between lipid metabolism disturbances and inflammatory processes.
Anastasia V. Poznyak+5 more
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NADPH oxidases: Current aspects and tools [PDF]
Reactive oxygen species (ROS) have been shown or at least suggested to play an essential role for cellular signaling as second messengers. NADPH oxidases represent a source of controlled ROS formation.
Katrin Schröder
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Activity-regulated growth of motoneurons at the neuromuscular junction is mediated by NADPH oxidases [PDF]
Neurons respond to changes in the levels of activity they experience in a variety of ways, including structural changes at pre- and postsynaptic terminals.
Daniel Sobrido-Cameán+4 more
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(Poly)phenols and the regulation of NADPH oxidases [PDF]
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion (O2•-) and hydrogen peroxide (H2O2), and that are widely distributed in mammalian tissues.
Cesar G. Fraga+3 more
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Cross-Talk of NADPH Oxidases and Inflammation in Obesity [PDF]
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz+6 more
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Role of NADPH Oxidases in Stroke Recovery [PDF]
Stroke is one of the most significant causes of death and long-term disability globally. Overproduction of reactive oxygen species by NADPH oxidase (NOX) plays an important role in exacerbating oxidative stress and causing neuronal damage after a stroke.
Dong-Hee Choi, In-Ae Choi, Jongmin Lee
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Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis [PDF]
Increased oxidative stress in osteoarthritis (OA) cartilage mediates catabolic signal transduction leading to extracellular matrix degradation and chondrocyte apoptosis.
Jin Han+3 more
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Unraveling the Crosstalk between Lipids and NADPH Oxidases in Diabetic Kidney Disease [PDF]
Diabetic kidney disease (DKD) is a serious complication of diabetes mellitus and a leading cause of end-stage renal disease. Abnormal lipid metabolism and intrarenal accumulation of lipids have been shown to be strongly correlated with the development ...
Rachel Njeim+2 more
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