Results 1 to 10 of about 48,906 (319)

NADPH Oxidases in Aortic Aneurysms [PDF]

Antioxidants, 2022
Abdominal aortic aneurysms (AAAs) are a progressive dilation of the infrarenal aorta and are characterized by inflammatory cell infiltration, smooth muscle cell migration and proliferation, and degradation of the extracellular matrix.
Morgan Salmon
doaj   +4 more sources

NADPH Oxidases in Pain Processing [PDF]

Antioxidants, 2022
Inflammation or injury to the somatosensory nervous system may result in chronic pain conditions, which affect millions of people and often cause major health problems.
Wiebke Kallenborn-Gerhardt, Katrin Schröder, Achim Schmidtko   +2 more
doaj   +5 more sources

NADPH Oxidases and Their Role in Atherosclerosis [PDF]

Biomedicines, 2020
The current view on atherosclerosis positions it as a multifactorial disorder that results from the interplay between lipid metabolism disturbances and inflammatory processes.
Anastasia V. Poznyak, Andrey V. Grechko, Varvara A. Orekhova, Victoria Khotina, Ekaterina A. Ivanova, Alexander N. Orekhov   +5 more
doaj   +6 more sources

NADPH oxidases: Current aspects and tools [PDF]

Redox Biology, 2020
Reactive oxygen species (ROS) have been shown or at least suggested to play an essential role for cellular signaling as second messengers. NADPH oxidases represent a source of controlled ROS formation.
Katrin Schröder
doaj   +7 more sources

Activity-regulated growth of motoneurons at the neuromuscular junction is mediated by NADPH oxidases [PDF]

Frontiers in Cellular Neuroscience, 2023
Neurons respond to changes in the levels of activity they experience in a variety of ways, including structural changes at pre- and postsynaptic terminals.
Daniel Sobrido-Cameán, Matthew C. W. Oswald, David M. D. Bailey, Amrita Mukherjee, Matthias Landgraf   +4 more
doaj   +2 more sources

(Poly)phenols and the regulation of NADPH oxidases [PDF]

Redox Biology, 2023
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion (O2•-) and hydrogen peroxide (H2O2), and that are widely distributed in mammalian tissues.
Cesar G. Fraga, Patricia I. Oteiza, Ezequiel J. Hid, Monica Galleano   +3 more
doaj   +2 more sources

Cross-Talk of NADPH Oxidases and Inflammation in Obesity [PDF]

Antioxidants, 2023
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz, Heike Brendel, Patrick Diaba-Nuhoho, Rusan Catar, Nikolaos Perakakis, Christian Wolfrum, Stefan R. Bornstein   +6 more
doaj   +2 more sources

Role of NADPH Oxidases in Stroke Recovery [PDF]

Antioxidants
Stroke is one of the most significant causes of death and long-term disability globally. Overproduction of reactive oxygen species by NADPH oxidase (NOX) plays an important role in exacerbating oxidative stress and causing neuronal damage after a stroke.
Dong-Hee Choi, In-Ae Choi, Jongmin Lee
doaj   +2 more sources

Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis [PDF]

Antioxidants, 2022
Increased oxidative stress in osteoarthritis (OA) cartilage mediates catabolic signal transduction leading to extracellular matrix degradation and chondrocyte apoptosis.
Jin Han, Donghwi Park, Ji Young Park, Seungwoo Han   +3 more
doaj   +2 more sources

Inhibiting NADPH Oxidases to Target Vascular and Other Pathologies: An Update on Recent Experimental and Clinical Studies [PDF]

Biomolecules, 2022
Reactive oxygen species (ROS) can be beneficial or harmful in health and disease. While low levels of ROS serve as signaling molecules to regulate vascular tone and the growth and proliferation of endothelial cells, elevated levels of ROS contribute to ...
Anthony L. Sylvester, David X. Zhang, Sophia Ran, Natalya S. Zinkevich   +3 more
doaj   +2 more sources