Results 1 to 10 of about 296,542 (336)
NADPH Oxidases in Aortic Aneurysms [PDF]
Antioxidants, 2022 Abdominal aortic aneurysms (AAAs) are a progressive dilation of the infrarenal aorta and are characterized by inflammatory cell infiltration, smooth muscle cell migration and proliferation, and degradation of the extracellular matrix.
Morgan Salmon
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NADPH Oxidases and Their Role in Atherosclerosis [PDF]
Biomedicines, 2020 The current view on atherosclerosis positions it as a multifactorial disorder that results from the interplay between lipid metabolism disturbances and inflammatory processes.
Anastasia V. Poznyak +5 more
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NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors. [PDF]
J Med Chem, 2023 NADPH oxidases (NOXs) form a family of electron-transporting membrane enzymes whose main function is reactive oxygen species (ROS) generation. Strong evidence suggests that ROS produced by NOX enzymes are major contributors to oxidative damage under ...
Cipriano A +6 more
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Activity-regulated growth of motoneurons at the neuromuscular junction is mediated by NADPH oxidases [PDF]
Frontiers in Cellular Neuroscience, 2023 Neurons respond to changes in the levels of activity they experience in a variety of ways, including structural changes at pre- and postsynaptic terminals.
Daniel Sobrido-Cameán +4 more
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NADPH Oxidases in Pain Processing [PDF]
Antioxidants, 2022 Inflammation or injury to the somatosensory nervous system may result in chronic pain conditions, which affect millions of people and often cause major health problems.
Wiebke Kallenborn-Gerhardt +2 more
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The Role of Oxidative Stress in NAFLD-NASH-HCC Transition-Focus on NADPH Oxidases. [PDF]
Biomedicines, 2021 A peculiar role for oxidative stress in non-alcoholic fatty liver disease (NAFLD) and its transition to the inflammatory complication non-alcoholic steatohepatitis (NASH), as well as in its threatening evolution to hepatocellular carcinoma (HCC), is ...
Gabbia D, Cannella L, De Martin S.
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NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology. [PDF]
Antioxidants (Basel), 2021 The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first identified in the membrane of phagocytic cells. For many years, its only known role was in immune defense, where its ROS production leads to the destruction of pathogens by ...
Vermot A +3 more
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(Poly)phenols and the regulation of NADPH oxidases [PDF]
Redox Biology, 2023 Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that generate superoxide anion (O2•-) and hydrogen peroxide (H2O2), and that are widely distributed in mammalian tissues.
Cesar G. Fraga +3 more
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Cross-Talk of NADPH Oxidases and Inflammation in Obesity [PDF]
Antioxidants, 2023 Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz +6 more
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Pathophysiology and Therapeutic Potential of NADPH Oxidases in Ischemic Stroke-Induced Oxidative Stress. [PDF]
Oxid Med Cell Longev, 2021 Stroke is a leading cause of death and disability in humans. The excessive production of reactive oxygen species (ROS) is an important contributor to oxidative stress and secondary brain damage after stroke.
Duan J +5 more
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