Results 31 to 40 of about 74,065 (268)

Reno-Protective Effect of GLP-1 Receptor Agonists in Type1 Diabetes: Dual Action on TRPC6 and NADPH Oxidases

Biomedicines, 2021
Diabetic kidney disease (DKD), a serious diabetic complication, results in podocyte loss and proteinuria through NADPH oxidases (NOX)-mediated ROS production.
Natalie Youssef, Mohamed Noureldein, Rachel Njeim, Hilda E. Ghadieh, Frederic Harb, Sami T. Azar, Nassim Fares, Assaad A. Eid   +7 more
doaj   +1 more source

ANXUR receptor-like kinases coordinate cell wall integrity with growth at the pollen tube tip via NADPH oxidases. [PDF]

PLoS Biology, 2013
It has become increasingly apparent that the extracellular matrix (ECM), which in plants corresponds to the cell wall, can influence intracellular activities in ways that go far beyond their supposedly passive mechanical support. In plants, growing cells
Aurélien Boisson-Dernier, Dmytro S Lituiev, Anna Nestorova, Christina Maria Franck, Sharme Thirugnanarajah, Ueli Grossniklaus   +5 more
doaj   +1 more source

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration [PDF]

, 2010
Ischemic stroke is the second leading cause of death worldwide. Only one moderately effective therapy exists, albeit with contraindications that exclude 90% of the patients.
Shah, Ajay M., Sven G. Meuth, de Angelis, MH, Henrike Grund, Schmidt, HHHW, Grund, Henrike, Schuhmann, M.K., Hrabě de Angelis, M., Sabine Meurer, Schuhmann, Michael, Schrewe, A., Stoll, G., Peter Kraft, Martin Hrabé de Angelis, Barit, David, Barit, D., Schwarz, Tobias, de Angelis, Martin Hrabe, Stoll, Guido, Shah, AM, Klopstock, T., Weissmann, N, Schrewe, A, Mittal, M, Herrmann, A.M., Jones, Emma, Schmidt, Harald, Konstanze Barthel, Gailus-Durner, Valérie, Hrabé de Angelis, Martin, Kraft, Peter, Becker, L., Fuchs, H, Jandeleit-Dahm, Karin, Anja Schrewe, Harald H. H. W, Herrmann, AM, David Barit, Sven G Meuth, Meurer, S., Weissmann, Norbert, Schmidt, H.H., Michael K. Schuhmann, Kraft, P., Armitage, Melanie, Schuhmann, Michael K., Weissmann, N., Meuth, SG, Schwarz, T, Karin Jandeleit-Dahm, Barthel, Konstanze, Herrmann, Alexander M., Stoll, G, Meurer, Sabine, Schmidt, Harald H. H. W., Guido Stoll, Wingler, K., Christian Geis, Mittal, Manish, Lore Becker, Schrewe, Anja, Klopstock, Thomas, Fuchs, Helmut, Shah, A.M., Jandeleit-Dahm, K, Gailus-Durner, V, Barthel, K., Ajay M. Shah, Klopstock, T, Manish Mittal, Armitage, Melanie E., Meuth, S.G., Shah, Ajay, Norbert Weissmann, Harald H. H. W. Schmidt, Kraft, P, Michael K Schuhmann, Hrabe ́ De Angelis, Grund, H, Meuth, Sven, Meuth, Sven G., Jones, E., Thomas Klopstock, Geis, C, Schuhmann, MK, Tobias Schwarz, Grund, H., Kleinschnitz, Christoph, Melanie E Armitage, Barthel, K, Meurer, S, Kleinschnitz, C, Fuchs, H., Armitage, ME, Kleinschnitz, C., Kirstin Wingler, Valérie Gailus-Durner, Geis, Christian, Geis, C., Jones, E, Karin J, Gailus-Durner, V., Emma Jones, Becker, L, Jandeleit-Dahm, Karin A., Wingler, Kirstin, Helmut Fuchs, Mittal, M., Schwarz, T., Armitage, M.E., Er M. Herrmann, Jandeleit-Dahm, K., Harald H H W Schmidt, Becker, Lore, Ajay M Shah, de Angelis, Martin, Christoph Kleinschnitz, Herrmann, Alexander, Alexander M. Herrmann, Wingler, K, Alexander M Herrmann, Melanie E. Armitage, Barit, D, Kraft Peter, Mittal Manish, Klopstock Thomas, Meurer Sabine, Schwarz Tobias, Jones Emma, Schuhmann Michael K., Barit David, Barthel Konstanze, Geis Christian, Schmidt Harald H. H. W., de Angelis Martin Hrabé, Fuchs Helmut, Kleinschnitz Christoph, Armitage Melanie E., Kleinschnitz, C. ; Grund, H. ; Wingler, K. ; Armitage, M.E. ; Jones, E. ; Mittal, M. ; Barit, D. ; Schwarz, T. ; Geis, C. ; Kraft, P. ; Barthel, K. ; Schuhmann, M.K. ; Herrmann, A.M. ; Meuth, S.G. ; Stoll, G. ; Meurer, S. ; Schrewe, A. ; Becker, L. ; Gailus-Durner, V. ; Fuchs, H. ; Klopstock, T. ; Hrabé de Angelis, M. ; Jandeleit-Dahm, K. ; Shah, A.M. ; Weissmann, N. ; Schmidt, H.H., Wingler Kirstin, Stoll Guido, Weissmann Norbert, Schrewe Anja, Jandeleit-Dahm Karin, Meuth Sven G., Shah Ajay M., Herrmann Alexander M., Grund Henrike, Gailus-Durner Valérie, Becker Lore   +149 more
core   +1 more source

NADPH oxidase (NOX) in the heart : the interplay of NOX-derived ROS in β1-integrin-induced survival signalling [PDF]

, 2011
Moderate levels of reactive oxygen species (ROS) act as mediators in cellular signalling processes. An important source of cardiac ROS is the highly expressed NADPH oxidase (NOX) family isoform NOX2. However, little is known about whether NOX-derived ROS
Rosc-Schlüter, Berit Ines
core   +1 more source

NADPH oxidase 4 and its role in the cardiovascular system

Vascular Biology, 2019
The heart relies on complex mechanisms that provide adequate myocardial oxygen supply in order to maintain its contractile function. At the cellular level, oxygen undergoes one electron reduction to superoxide through the action of different types of ...
Stephen P Gray, Ajay M Shah, Ioannis Smyrnias   +2 more
doaj   +1 more source

Activity-regulated growth of motoneurons at the neuromuscular junction is mediated by NADPH oxidases [PDF]

, 2022
Neurons respond to changes in the levels of activity they experience in a variety of ways, including structural changes at pre- and postsynaptic terminals.
Sobrido-Cameán D, Oswald MCW, Bailey DMD, Mukherjee A, Landgraf M.   +4 more
europepmc   +3 more sources

Potential role of NADPH-oxidase in early steps of lead-induced oxidative burst in Vicia faba roots [PDF]

, 2008
The mechanism of oxidative burst induced by lead in Vicia faba excised roots was investigated by luminol-dependent chemiluminescence. Results showed that lead triggered a rapid and dose-dependent increase in chemiluminescence production.
Perchet, Geoffrey-Thibault, Cecchi, M., Silvestre, Jérôme, Pinelli, Eric, Pourrut, Bertrand, Cecchi, Marie, Guiresse, Agnès Maritchù, Guiresse, Maritxu   +7 more
core   +1 more source

Signaling through NADPH oxidases [PDF]

, 2006
Vascular remodeling processes are characterized by increased proliferation of vascular cells and a prothrombotic state. Coagulation factors and vasoactive peptides have been suggested to contribute to these processes.
Djordjevic, Talija
core   +1 more source

NADPH Oxidase as a Therapeutic Target for Neuroprotection against Ischaemic Stroke: Future Perspectives

Brain Sciences, 2013
Oxidative stress caused by an excess of reactive oxygen species (ROS) is known to contribute to stroke injury, particularly during reperfusion, and antioxidants targeting this process have resulted in improved outcomes experimentally. Unfortunately these
Carli L. Roulston, Sarah K. McCann
doaj   +1 more source

Effects of Angiotensin II on the Cerebral Circulation: Role of Oxidative Stress

Frontiers in Physiology, 2013
Oxidative stress has emerged as a key component of many diseases that affect the vasculature. Oxidative stress is characterized as a cellular environment where the generation of oxidant molecules overwhelms endogenous antioxidant defense mechanisms ...
Travice Michael De Silva, Frank eFaraci
doaj   +1 more source