Results 11 to 20 of about 48,906 (319)
Unraveling the Crosstalk between Lipids and NADPH Oxidases in Diabetic Kidney Disease [PDF]
Pharmaceutics, 2023 Diabetic kidney disease (DKD) is a serious complication of diabetes mellitus and a leading cause of end-stage renal disease. Abnormal lipid metabolism and intrarenal accumulation of lipids have been shown to be strongly correlated with the development ...
Rachel Njeim +2 more
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Reno-Protective Effect of GLP-1 Receptor Agonists in Type1 Diabetes: Dual Action on TRPC6 and NADPH Oxidases [PDF]
Biomedicines, 2021 Diabetic kidney disease (DKD), a serious diabetic complication, results in podocyte loss and proteinuria through NADPH oxidases (NOX)-mediated ROS production.
Natalie Youssef +7 more
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Yin and Yang of NADPH Oxidases in Myocardial Ischemia-Reperfusion [PDF]
Antioxidants, 2022 Oxidative stress is critically involved in the pathophysiology of myocardial ischemic-reperfusion (I/R) injury. NADPH oxidase (Nox) 2 and 4, major sources of reactive oxygen species (ROS) in cardiomyocytes, are upregulated in response to I/R. Suppression
Shouji Matsushima, Junichi Sadoshima
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NADPH Oxidase and Neurodegeneration [PDF]
Current Neuropharmacology, 2012 NADPH oxidase (Nox) is a unique, multi-protein, electron transport system that produces large amounts of superoxide via the reduction of molecular oxygen. Nox-derived reactive oxygen species (ROS) are known to be involved in a variety of physiological processes, including host defense and signal transduction.
Marina S. Hernandes, Luiz R.G. Britto
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Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]
, 2016 The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa +8 more
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Frontiers in Pharmacology, 2021 Metabolic syndrome (MetS), a complex of interrelated risk factors for cardiovascular disease and diabetes, is comprised of central obesity (increased waist circumference), hyperglycemia, dyslipidemia (high triglyceride blood levels, low high-density ...
Hewang Lee, Pedro A Jose, Pedro A Jose
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Regulation of Plant NADPH Oxidase [PDF]
Plant Signaling & Behavior, 2007 The production of Reactive Oxygen Species (ROS) is one of the key events occurring during the response of plants to environmental changes, and contributing to establish adaptive signaling pathways. A plasma membrane bound NADPH oxidase enzyme has been evidenced as the ROS producing system in various plant-microorganisms interactions.
Elmayan, Taline, Simon-Plas, Françoise
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NADPH Oxidases in Vascular Pathology [PDF]
Antioxidants & Redox Signaling, 2014 Reactive oxygen species (ROS) play a critical role in vascular disease. While there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases play a central role. They are a source of "kindling radicals," which affect other enzymes, such as nitric oxide synthase endothelial nitric oxide synthase or xanthine oxidase.
Tomasz J. Guzik +3 more
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Haematologica, 2020 The regulation of protein function by reversible oxidation is increasingly recognized as a key mechanism for the control of cellular signaling, modulating crucial biological processes such as cell differentiation.
Rodrigo Prieto-Bermejo +5 more
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The Arabidopsis NADPH oxidases RbohD and RbohF display differential expression patterns and contributions during plant immunity [PDF]
, 2016 Plant NADPH oxidases, also known as respiratory burst oxidase homologues (RBOHs), produce reactive oxygen species (ROS) that perform a wide range of functions.
Antonio Molina +6 more
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