Results 241 to 250 of about 74,065 (268)

The NADPH Oxidase Family and Its Inhibitors

Antioxidants & Redox Signaling, 2020
Significance: The oxidative stress, resulting from an imbalance in the production and scavenging of reactive oxygen species (ROS), is known to be involved in the development and progression of several pathologies. The excess of ROS production is often due to an overactivation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) and for
Chocry, Mathieu, Leloup, Ludovic
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NADPH oxidase and heart failure

Current Opinion in Pharmacology, 2006
Reactive oxygen species play important roles in the pathophysiology of chronic heart failure secondary to chronic left ventricular hypertrophy or myocardial infarction. Reactive oxygen species influence several components of the phenotype of the failing heart, including contractile function, interstitial fibrosis, endothelial dysfunction and myocyte ...
Murdoch, Colin E., Grieve, David J., Cave, Alison C., Looi, Yee Hoo, Shah, Ajay M.   +4 more
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NADPH oxidases and cardiac remodelling

Heart Failure Reviews, 2010
A heart under chronic stress undergoes cardiac remodelling, a process that comprises structural and functional changes including cardiomyocyte hypertrophy, interstitial fibrosis, contractile dysfunction, cell death and ventricular dilatation. Reactive oxygen species (ROS)-dependent modulation of intracellular signalling is implicated in the development
Nabeebaccus, Adam, Zhang, Min, Shah, Ajay M.   +2 more
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Assembly of the phagocyte NADPH oxidase

Histochemistry and Cell Biology, 2004
Stimulated phagocytes undergo a burst in respiration whereby molecular oxygen is converted to superoxide anion through the action of an NADPH-dependent oxidase. The multicomponent phagocyte oxidase is unassembled and inactive in resting cells but assembles at the plasma or phagosomal membrane upon phagocyte activation.
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The NADPH‐Dependent Oxidase of Phagocytes

Proceedings of the Association of American Physicians, 1999
Polymorphonuclear leukocytes (PMNs) represent a prominent cellular element in the innate immune system, serving to ingest exogenous particles and microbes and to kill phagocytosed microorganisms. The microbicidal activity of PMNs depends on the interactions of a broad array of potent systems, including relatively stable degradative proteins as well as ...
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NADPH AND NADPH OXIDASE

2006
A.B. Fisher, Q. Zhang
openaire   +1 more source

NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis

Arteriosclerosis, Thrombosis, and Vascular Biology, 2021
Reiner Mailer, Katrin Schröder, Dina Vara   +2 more
exaly  

NADPH Oxidases: The Vital Performers and Center Hubs during Plant Growth and Signaling

Cells, 2020
Kun-Ming Chen, Liu Wenting, Chun-Hong Hu   +2 more
exaly  

Regulation of Metabolic Processes by Hydrogen Peroxide Generated by NADPH Oxidases

Processes, 2020
Hector Vázquez-Meza
exaly  

The activation of the electrogenic NADPH oxidase

Biochemical Society Transactions, 1991
J B, Chappell, L M, Henderson
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