Results 21 to 30 of about 30,089 (299)

Cyba-deficient mice display an increase in hematopoietic stem cells and an overproduction of immunoglobulins

open access: yesHaematologica, 2020
The regulation of protein function by reversible oxidation is increasingly recognized as a key mechanism for the control of cellular signaling, modulating crucial biological processes such as cell differentiation.
Rodrigo Prieto-Bermejo   +5 more
doaj   +1 more source

NADPH oxidases in Parkinson’s disease: a systematic review

open access: yesMolecular Neurodegeneration, 2017
Parkinson’s disease (PD) is a progressive movement neurodegenerative disease associated with a loss of dopaminergic neurons in the substantia nigra of the brain. Oxidative stress, a condition that occurs due to imbalance in oxidant and antioxidant status,
Karim Belarbi   +4 more
doaj   +1 more source

ANXUR receptor-like kinases coordinate cell wall integrity with growth at the pollen tube tip via NADPH oxidases. [PDF]

open access: yesPLoS Biology, 2013
It has become increasingly apparent that the extracellular matrix (ECM), which in plants corresponds to the cell wall, can influence intracellular activities in ways that go far beyond their supposedly passive mechanical support. In plants, growing cells
Aurélien Boisson-Dernier   +5 more
doaj   +1 more source

The Relationship of NADPH Oxidases and Heme Peroxidases: Fallin' in and Out

open access: yesFrontiers in Immunology, 2019
Peroxidase enzymes can oxidize a multitude of substrates in diverse biological processes. According to the latest phylogenetic analysis, there are four major heme peroxidase superfamilies. In this review, we focus on certain members of the cyclooxygenase-
Gábor Sirokmány   +3 more
doaj   +1 more source

A Role for Reactive Oxygen Species Produced by NADPH Oxidases in the Embryo and Aleurone Cells in Barley Seed Germination.

open access: yesPLoS ONE, 2015
Reactive oxygen species (ROS) promote the germination of several seeds, and antioxidants suppress it. However, questions remain regarding the role and production mechanism of ROS in seed germination. Here, we focused on NADPH oxidases, which produce ROS.
Yushi Ishibashi   +8 more
doaj   +1 more source

NADPH oxidase 4 and its role in the cardiovascular system

open access: yesVascular Biology, 2019
The heart relies on complex mechanisms that provide adequate myocardial oxygen supply in order to maintain its contractile function. At the cellular level, oxygen undergoes one electron reduction to superoxide through the action of different types of ...
Stephen P Gray   +2 more
doaj   +1 more source

NADPH Oxidases Act as Key Enzyme on Germination and Seedling Growth in Barley (Hordeum vulgare L.)

open access: yesPlant Production Science, 2010
Reactive oxygen species (ROS) play an important role in seed germination. Although hydrogen peroxide (H2O2), a type of ROS, enhances the germination rate of various plant seeds, little is known about the mechanism.
Yushi Ishibashi   +4 more
doaj   +1 more source

NADPH Oxidase as a Therapeutic Target for Neuroprotection against Ischaemic Stroke: Future Perspectives

open access: yesBrain Sciences, 2013
Oxidative stress caused by an excess of reactive oxygen species (ROS) is known to contribute to stroke injury, particularly during reperfusion, and antioxidants targeting this process have resulted in improved outcomes experimentally. Unfortunately these
Carli L. Roulston, Sarah K. McCann
doaj   +1 more source

Effects of Angiotensin II on the Cerebral Circulation: Role of Oxidative Stress

open access: yesFrontiers in Physiology, 2013
Oxidative stress has emerged as a key component of many diseases that affect the vasculature. Oxidative stress is characterized as a cellular environment where the generation of oxidant molecules overwhelms endogenous antioxidant defense mechanisms ...
Travice Michael De Silva, Frank eFaraci
doaj   +1 more source

NADPH Oxidases Are Involved in Differentiation and Pathogenicity in Botrytis cinerea

open access: yesMolecular Plant-Microbe Interactions, 2008
Nicotinamide adenine dinucleotide (NADPH) oxidases have been shown to be involved in various differentiation processes in fungi. We investigated the role of two NADPH oxidases in the necrotrophic phytopathogenic fungus, Botrytis cinerea. The genes bcnoxA
Nadja Segmüller   +5 more
doaj   +1 more source

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