Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri [PDF]
PLoS Pathogens, 2018 Naegleria fowleri is a free-living amoeba that can also act as an opportunistic pathogen causing severe brain infection, primary amebic meningoencephalitis (PAM), in humans.
Wenxu Zhou +2 more
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Detection and identification of Naegleria species along with Naegleria fowleri in the tap water samples [PDF]
BMC Medical GenomicsNaegleria fowleri, the causative agent of Primary Amoebic Meningoencephalitis (PAM), is commonly found in warm freshwater environments and can enter the brain through nasal passages during activities like swimming or ablution.
Muhammad Aurongzeb +7 more
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Potential Inhibitors of Human–Naegleria fowleri Interactions: An In Vitro Extracellular Matrix-Based Model [PDF]
Marine DrugsPrimary amoebic meningoencephalitis (PAM) is a rapidly progressive and fulminant disease that affects the central nervous system caused by the free-living amoeba Naegleria fowleri.
Javier Chao-Pellicer +7 more
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Naegleria fowleri: Pathogenesis, Diagnosis, and Treatment Options [PDF]
Antimicrobial Agents and Chemotherapy, 2015 ABSTRACT Naegleria fowleri has generated tremendous media attention over the last 5 years due to several high-profile cases. Several of these cases were followed very closely by the general public. N.
Eddie, Grace, Scott, Asbill, Kris, Virga
exaly +3 more sources
Detection and Confirmation of Naegleria fowleri in a Primary Amebic Meningoencephalitis Patient Using a Molecular Approach [PDF]
Journal of Parasitology ResearchThe Naegleria fowleri amoeba stands as the primary culprit behind primary amebic meningoencephalitis (PAM), presenting a substantial global public health concern. In recent years, over 17 cases of PAM have been reported in Karachi, Pakistan, highlighting
Muhammad Aurongzeb +11 more
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Advances in the study of extracellular vesicles of Naegleria fowleri and their role in contact-independent pathogenic mechanisms [PDF]
Parasites & VectorsBackground Extracellular vesicles (EVs) are spherical membrane particles released by prokaryotic and eukaryotic cells. EVs produced by pathogenic organisms are known to play a role in host-pathogen interactions; however, despite some reports on Naegleria
Ismael Castelan-Ramírez +7 more
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Fatal Case of Naegleria fowleri Primary Amebic Meningoencephalitis from Indoor Surfing Center, Taiwan, 2023 [PDF]
Emerging Infectious DiseasesWe investigated a fatal case of primary amoebic meningoencephalitis from an indoor surfing center in Taiwan. The case was detected through encephalitis syndromic surveillance.
Hsin-Yi Wei +6 more
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Etymologia: Naegleria fowleri [PDF]
Emerging Infectious Diseases, 2011 Nancy Männikkö
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Growth dynamic of biofilm-associated Naegleria fowleri in freshwater on various materials [PDF]
Frontiers in MicrobiologyIn industrial water systems, the occurrence of biofilm-associated pathogenic free-living amoebae (FLA) such as Naegleria fowleri is a potential hygienic problem, and factors associated with its occurrence remain poorly understood.
Sébastien Goudot +5 more
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First evidence of free-living Naegleria species in recreational lakes of Alberta, Canada
Journal of Water and Health, 2023 Rising temperatures are increasing environmental habitats for thermotolerant pathogens, such as the so-called ‘brain-eating amoeba’, Naegleria fowleri. To the best of our knowledge, however, Naegleria species have not been reported in environmental water
Rafik Dey +3 more
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