Results 1 to 10 of about 5,412 (250)

Detection and Confirmation of Naegleria fowleri in a Primary Amebic Meningoencephalitis Patient Using a Molecular Approach. [PDF]

J Parasitol Res
The Naegleria fowleri amoeba stands as the primary culprit behind primary amebic meningoencephalitis (PAM), presenting a substantial global public health concern. In recent years, over 17 cases of PAM have been reported in Karachi, Pakistan, highlighting
Aurongzeb M, Nazir MA, Yasmin R, Kiran A, Fatima R, Ali R, Khan SA, Ul-Haq A, Al-Regaiey K, Abualait T, Kaleem I, Bashir S.   +11 more
europepmc   +4 more sources

Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri [PDF]

BMC Biology, 2021
Background The opportunistic pathogen Naegleria fowleri establishes infection in the human brain, killing almost invariably within 2 weeks. The amoeba performs piece-meal ingestion, or trogocytosis, of brain material causing direct tissue damage and ...
Chiu, Charles, Dacks, Joel B., Elias, Marek, Fritz-Laylin, Lilian, Ginger, Michael L., Greninger, Alex, Herman, Emily K., MacIntyre, Georgina, Marciano-Cabral, Francine, Miller, Haylea C., Morgan, Matthew J., Muller, Norbert, Najle, Sebastian Rodrigo, Puzon, Geoffrey J., Ramirez-Macias, Inmaculada, Slamovits, Claudio H., Tsaousis, Anastasios D., van der Giezen, Mark, Vargova, Romana, Velle, Katrina, Walsh, Tom, Weirauch, Matthew T., Wittwer, Mattias, Zahonova, Kristina, Zysset-Burri, Denise C.   +24 more
core   +4 more sources

Naegleria fowleri from Pakistan Has Type-2 Genotype

Iranian Journal of Parasitology, 2022
Background: Primary amoebic meningoencephalitis (PAM) is an acute and fulminant CNS infection caused by Naegleria fowleri. Recreational activities and ritual ablution with contaminated warm fresh water are the main reason of PAM.
Muhammad Aurongzeb, Yasmeen Rashid, Syed Habib Ahmed Naqvi, Ambrina Khatoon, Sadia Abdul Haq, Muhammad Kamran Azim, Imdad Kaleem, Shahid Bashir   +7 more
doaj   +2 more sources

Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis

Data in Brief, 2018
The recombinant TvCP4 prepro region (ppTvCP4r) acts as an exogenous inhibitor of cathepsin L-like CPs from Trichomonas vaginalis (Cárdenas-Guerra et al., 2015 [1]). Here, we present the dataset of the trichomonad ppTvCP4r inhibitory effect against the CP
Rosa E. Cárdenas-Guerra, Moisés Martínez-Castillo, Jaime Ortega-López, Mineko Shibayama, Rossana Arroyo   +4 more
doaj   +2 more sources

Potential Inhibitors of Human-<i>Naegleria fowleri</i> Interactions: An In Vitro Extracellular Matrix-Based Model. [PDF]

Mar Drugs
Primary amoebic meningoencephalitis (PAM) is a rapidly progressive and fulminant disease that affects the central nervous system caused by the free-living amoeba Naegleria fowleri.
Chao-Pellicer J, Arberas-Jiménez I, Sifaoui I, Díaz-Marrero AR, Fernández JJ, Jamerson M, Piñero JE, Lorenzo-Morales J.   +7 more
europepmc   +2 more sources

Detection and identification of Naegleria species along with Naegleria fowleri in the tap water samples. [PDF]

BMC Med Genomics
Naegleria fowleri, the causative agent of Primary Amoebic Meningoencephalitis (PAM), is commonly found in warm freshwater environments and can enter the brain through nasal passages during activities like swimming or ablution.
Aurongzeb M, Fatima SZ, Hussain SI, Rashid Y, Aziz T, Alhomrani M, Alsanie WF, Alamri AS.   +7 more
europepmc   +2 more sources

Computational identification of putative miRNAs and their target genes in pathogenic amoeba Naegleria fowleri [PDF]

, 2015
Naegleria fowleri is a parasitic unicellular free living eukaryotic amoeba. The parasite spreads through contaminated water and causes primary amoebic meningoencephalitis (PAM). Therefore, it is of interest to understand its molecular pathogenesis. Hence,
Padmashree, D., Swamy, N.R.
core   +3 more sources

Detection of Naegleria Species in Environmental Samples from Peninsular Malaysia [PDF]

PLoS ONE, 2011
In Malaysia, researchers and medical practitioners are unfamiliar with Naegleria infections. Thus little is known about the existence of pathogenic Naegleria fowleri, and the resultant primary amoebic meningoencephalitis (PAM) is seldom included in the ...
Arine Fadzlun Ahmad, C MaCarthy, DC Warhurst, FM Welling, I Init, Init Ithoi, J Felsenstein, JF De Jonckheere, JF De Jonckheere, JF De Jonckheere, JF De Jonckheere, JF De Jonckheere, JH Diaz, JL Griffin, Joon Wah Mak, KB Sheehan, M Carraway, M Kimura, M Pélandakis, M Pélandakis, N Saitou, R Chenna, RF Carter, RL Tyndal, Rohela Mahmud, RS Felleisen, RV Lawande, S Kumar, S Shakoor, S Tiewcharoen, SF Altschul, Stefan Bereswill, T Garstecki, V Wiwanitkit, Veeranoot Nissapatorn, Y Sugita, Yee Ling Lau   +36 more
core   +5 more sources

Fatal Case of Naegleria fowleri Primary Amebic Meningoencephalitis from Indoor Surfing Center, Taiwan, 2023. [PDF]

Emerg Infect Dis
We investigated a fatal case of primary amoebic meningoencephalitis from an indoor surfing center in Taiwan. The case was detected through encephalitis syndromic surveillance.
Wei HY, Lai YW, Li SY, Lee YI, Hu MK, Ji DD, Su CP.   +6 more
europepmc   +2 more sources

Advances in the study of extracellular vesicles of Naegleria fowleri and their role in contact-independent pathogenic mechanisms. [PDF]

Parasit Vectors
Background Extracellular vesicles (EVs) are spherical membrane particles released by prokaryotic and eukaryotic cells. EVs produced by pathogenic organisms are known to play a role in host-pathogen interactions; however, despite some reports on Naegleria
Castelan-Ramírez I, Flores-Maldonado C, Hernández-Martínez D, Salazar-Villatoro L, Saucedo-Campos AD, Segura-Cobos D, Méndez-Cruz AR, Omaña-Molina M.   +7 more
europepmc   +2 more sources