Results 51 to 60 of about 1,770 (171)

Interactions between Naegleria fowleri and Legionella pneumophila [PDF]

open access: yesInfection and Immunity, 1985
Using electron microscopy we documented some of the intracellular events that occur in Naegleria fowleri suspended in Page amoeba saline after ingestion of Legionella pneumophila. Photomicrographs showed intracellular vacuoles containing bacteria in the process of binary fission that was accompanied by alignment of mitochondria and ribosome-like ...
A L, Newsome   +3 more
openaire   +2 more sources

Rare Infectious Diseases: Detection and Clinical Implications

open access: yesiLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian   +7 more
wiley   +1 more source

Copper Metabolism in Naegleria gruberi and Its Deadly Relative Naegleria fowleri

open access: yesFrontiers in Cell and Developmental Biology, 2022
Although copper is an essential nutrient crucial for many biological processes, an excessive concentration can be toxic and lead to cell death. The metabolism of this two-faced metal must be strictly regulated at the cell level. In this study, we investigated copper homeostasis in two related unicellular organisms: nonpathogenic Naegleria gruberi and ...
Ženíšková, Kateřina   +2 more
openaire   +3 more sources

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou   +18 more
wiley   +1 more source

A giant virus infecting the amoeboflagellate Naegleria

open access: yesNature Communications
Giant viruses (Nucleocytoviricota) are significant lethality agents of various eukaryotic hosts. Although metagenomics indicates their ubiquitous distribution, available giant virus isolates are restricted to a very small number of protist and algal ...
Patrick Arthofer   +12 more
doaj   +1 more source

Clinical, Laboratory Characteristics, and Microorganism Infection Status in Neonates With Meningitis in Vietnam: A Cross‐Sectional Descriptive Study

open access: yesInternational Journal of Pediatrics, Volume 2025, Issue 1, 2025.
Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham   +4 more
wiley   +1 more source

Role of protein arginine methyltransferase 1 in obesity‐related metabolic disorders: Research progress and implications

open access: yesDiabetes, Obesity and Metabolism, Volume 26, Issue 9, Page 3491-3500, September 2024.
Abstract Obesity has become a major global problem that significantly confers an increased risk of developing life‐threatening complications, including type 2 diabetes mellitus, fatty liver disease and cardiovascular diseases. Protein arginine methyltransferases (PRMTs) are enzymes that catalyse the methylation of target proteins.
Xiaolei Xuan   +6 more
wiley   +1 more source

Immunization of mice against Naegleria fowleri infection [PDF]

open access: yesInfection and Immunity, 1977
Naegleria fowleri produces fatal meningoencephalitis in humans and in experimentally infected laboratory animals. The course of the disease in mice is dependent upon the infecting dose of amoebae, route of inoculation, and prior exposure to Naegleria antigens. DUB/ICR mice were immunized by various routes and antigen preparations, held for 21 days, and,
D T, John, R R, Weik, A C, Adams
openaire   +2 more sources

Fossil Geyserite and Testate Amoebae in Geothermal Spring Vent Pools: Paleoecology and Variable Preservation Quality in Jurassic Sinter of Patagonia (Deseado Massif, Argentina)

open access: yesGeobiology, Volume 22, Issue 5, September/October 2024.
ABSTRACT Geyserite is a type of terrestrial siliceous hot spring deposit (sinter) formed subaerially in proximal vent areas, with near‐neutral pH, alkali chloride discharge fluids characterized by initial high temperatures (~73°C to up to 100°C) that fluctuate rapidly in relation to dynamic hydrology, seasonality, wind, and other environmental ...
Ana Julia Sagasti   +5 more
wiley   +1 more source

Population Structure in Naegleria fowleri as Revealed by Microsatellite Markers. [PDF]

open access: yesPLoS ONE, 2016
Naegleria sp. is a free living amoeba belonging to the Heterolobosea class. Over 40 species of Naegleria were identified and recovered worldwide in different habitats such as swimming pools, freshwater lakes, soil or dust. Among them, N.
Bénédicte Coupat-Goutaland   +6 more
doaj   +1 more source

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