Results 111 to 120 of about 54,810 (302)
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
A descriptive study of nail changes in systemic diseases
Background and Objectives: Nail findings may represent a part of the symptom complex that may be useful for the physical diagnosis. Thus, the present study was undertaken to know the nail changes in systemic diseases among patients attending the ...
Sanjay Ramachandra Thejaswi +5 more
core +1 more source
, 2015 Diagnosing nail matrix diseases requires knowledge of the nail matrix function and anatomy. This allows recognition of the clinical manifestations and assessment of potential surgical risk. Nail signs depend on the location within the matrix (proximal or
Josette André +5 more
core +1 more source
Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective
JEADV Clinical PracticeThis narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic ...
Elizabeth Botto +3 more
doaj +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Advanced Healthcare Materials, EarlyView.Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy
Advanced Healthcare Materials, EarlyView.This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su +8 more
wiley +1 more source
Nail disorders in infants and children.
, 2014 Nail diseases in infants and children are an uncommon cause of consultation and are often difficult to diagnose and to manage. This review will cover nail diseases that are most commonly seen in clinical practice, including congenital and hereditary ...
PIRACCINI, BIANCA MARIA +1 more
core +1 more source
Advanced Healthcare Materials, EarlyView.We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou +9 more
wiley +1 more source
Kuku Sebagai Petunjuk Penyakit Lain (Nail As A Hint Other Diseases) [PDF]
, 2018 Changes in the color and texture of the surface of the nail can reflect a variety of medical conditions. We can notice subtle change as variations, and often these imperfections form will not mean much to some people, but for the trained eye, nail ...
Anggowarsito, Jose L.
core
, 2019 Various advancements in the diagnosis and management of nail diseases have transpired in recent years. To provide the best care for patients with nail complaints, it is essential that physicians be updated on new diagnostic and treatment modalities.
Maddy, Austin J, Tosti, Antonella
core +1 more source