Results 91 to 100 of about 2,208,935 (290)

Synchronous subungual glomus tumors in the same finger Tumores glômicos subungueais sincrônicos no mesmo dedo

open access: yesAnais Brasileiros de Dermatologia, 2012
The glomus tumor is an uncommon benign neoplasm of glomus cells. In the majority of the cases it is presented as a solitary painful papule in the subungual region. We report a rare case of a patient with two individual synchronous glomus tumors under the
Nilton Di Chiacchio   +3 more
doaj   +1 more source

Nail colour changes (chromonychia)

open access: yes, 2005
There are some important points to note concerning the examination of abnormal nails for colour changes. The nails should be studied with the fingers completely relaxed and not pressed against any surface.

core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Investigation of Nailfold Capillary Structures Using Digital Dermatoscopy in Rheumatological Diseases

open access: yesArchives of Basic and Clinical Research
Objective: Evaluating the microvascular structure in rheumatological diseases provides important information for understanding the pathogenesis and clinical management of these diseases.
Haticetül Kübra Sarı, Şevki Özdemir
doaj   +1 more source

Nail trick

open access: yes, 2014
This activity proposes to balance 15 nails on the head of one nail. Nails can be balanced across the first nail if their weight is evenly distributed and if they can be stopped from slipping off.
Science Museum
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Tofacitinib successful treatment of idiopathic twenty-nail dystrophy: a case report

open access: yesJournal of Dermatological Treatment
Purpose Twenty-nail dystrophy (TND) is a chronic nail disorder affecting all or some nails and posing a significant therapeutic challenge for dermatologists.
Wenjun Zhao, Shijun Shan, Dongmei Liu
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Drug-induced nail diseases.

open access: yes, 2006
Although many nail disorders have been associated with drug intake, most reports are anecdotal. Most nail changes caused by drugs are the outcome of acute toxicity to the nail epithelia; nail symptoms depend on which nail structure is damaged.
IORIZZO, MATILDE   +3 more
core   +1 more source

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