Results 81 to 90 of about 129,447 (312)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Prevalence of Disorders Recorded in Dogs Attending Primary-Care Veterinary Practices in England [PDF]

, 2014
Purebred dog health is thought to be compromised by an increasing occurence of inherited diseases but inadequate prevalence data on common disorders have hampered efforts to prioritise health reforms. Analysis of primary veterinary practice clinical data
A Agresti, A Egenvall, A Egenvall, A Egenvall, A Egenvall, A Hillier, A Kathrani, A Neuber, AB Stone, AJ German, AJ German, AM Lourenço-Martins, B Wilson, BN Bonnett, C Albuquerque, C Mellersh, Cheryl S. Rosenfeld, CL Aragon, Dan G. O′Neill, Dave C. Brodbelt, David B. Church, DD Sleator, DN Irion, DR Ownby, E Friedmann, EM Lund, F Walsh, FC Calboli, FD McMillan, FJD Smith, G Chodick, G Dank, G Leroy, GC Knight, GM Gobar, GP Page, H Soll-Johanning, HD Pedersen, HE Hein, J Virués-Ortega, JE Houlton, JF Summers, JI Hudson, JK Murray, JLN Wood, JM Fleming, JS Rand, KD Mandl, L Asher, L Asher, L Kearsley-Fleet, LM Collins, LM Collins, M Aickin, MB Willis, MK Rust, MP Starkey, MR Slater, MW Neff, MY Powers, N Pearce, NJ Rooney, NJ Rooney, P Froom, P Royston, Paul D. McGreevy, PC Bartlett, PD McGreevy, PD McGreevy, Peter C. Thomson, PM Mountziaris, R Bender, R Feise, R Marsella, R Medzhitov, RM Batt, RMA Packer, S Brady, S Crispin, S Greenland, S Platt, SFJ Hodgman, T Lewis, T Lewis, TP Bellumori, TW Lewis, U John, VJ Adams, WB Lober, Å Vilson   +89 more
core   +3 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Macroscopic and dermoscopic evaluation used to differentiate subungual haemorrhage from melanocytic lesions [PDF]

Journal of Primary Health Care, 2020
INTRODUCTIONSubungual haemorrhage describes blood located between the nail matrix and nail plate caused by trauma. Lack of recalled trauma and long duration of nail pigmentation results in specialist referrals to rule out malignant pathology.
Amanda Oakley, Mirain Phillips
doaj  

Installation of insecticide-treated durable wall lining: evaluation of attachment materials and product durability under field conditions. [PDF]

, 2014
BACKGROUND: Insecticide-treated durable wall lining (DL) is a new method of vector control designed to supplement LLINs and overcome two inherent limitations of LLINs and IRS: nightly behavioural compliance and short residual activity, respectively.
Larsen, Marie Louise M, Messenger, Louisa A, Rowland, Mark, Thomas, John H   +3 more
core   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel

Case Reports in Dermatology, 2020
Pincer nail is a common condition characterized by excessive transverse nail curvature, progressively pinching the nail bed distally, resulting in cosmetic discomfort, pain and functional limitation.
Laura Vollono, Ester Del Duca, Sara Mazzilli, Luca Bianchi, Terenzio Cosio, Caterina Lanna, Elena Campione   +6 more
doaj   +1 more source

Nail disease in pemphigus vulgaris

Dermatology Online Journal, 2009
Patients affected by pemphigus vulgaris will occasionally present with associated and characteristic nail changes. This manuscript was prepared as a review of this unique presentation of pemphigus. Articles describing pemphigus vulgaris of the nail were compiled and reviewed and pertinent information was extracted to provide a concise analysis.
Serratos, Brittany Dusek, Rashid, Rashid M   +1 more
openaire   +4 more sources

Endoscopic optical coherence tomography with a flexible fiber bundle

, 2018
We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope design by ...
Ginner, Laurin, Kumar, Abhishek, Leitgeb, Rainer A., Salas, Matthias, Wartak, Andreas, Wurster, Lara M.   +5 more
core   +1 more source