Results 131 to 140 of about 9,255 (180)
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Immunological studies on Naja nigricollis antivenin
Toxicon, 1973Abstract Monovalent Naja nigricollis antivenin was prepared in horses using venom adsorbed to bentonite (first three injections) followed by increasing doses (up to 50 mg) of unmodified venom. The serum (1 ml) neutralized 51 ld 50 's of its homologous venom. Good neutralizing capacity (30–50 ld 50 's per ml) was also shown against venoms of N.
A H, Mohamed +2 more
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The effect of Naja nigricollis venom on blood clotting
Toxicon, 1971Abstract Naja nigricollis venom has an in vivo anticoagulant action which is heat-labile and is prevented by protamine and polyvalent horse anti-snake venom serum containing no specific antivenin against this venom. This anticoagulant action may be attributed partly to an anti-thromboplastin-like action and partly to heparin release.
A H, Mohamed +2 more
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Toxicon, 2021
Proteomics technologies enable a comprehensive study of complex proteins and their functions. The venom proteomes of three medically important Nigerian Elapidae snakes Naja haje, Naja katiensis and Naja nigricollis was studied using HILIC coupled with LC-MS/MS analysis. Results revealed a total of 57, 55, and 46 proteins in the venoms of N.
Fatima Amin, Adamude +6 more
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Proteomics technologies enable a comprehensive study of complex proteins and their functions. The venom proteomes of three medically important Nigerian Elapidae snakes Naja haje, Naja katiensis and Naja nigricollis was studied using HILIC coupled with LC-MS/MS analysis. Results revealed a total of 57, 55, and 46 proteins in the venoms of N.
Fatima Amin, Adamude +6 more
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Purification of a neurotoxin from the venom of Naja nigricollis
Biochimica et Biophysica Acta (BBA) - General Subjects, 1966A neurotoxin, called toxin α, has been isolated from the venom of Naja nigricollis by ion-exchange chromatography on Amberlite IRC-50. The yield of neurotoxin obtained corresponded to about 3% of crude venom, by weight. The neurotoxin was homogeneous by chromatography on IRC-50, free-zone electrophoresis, starch-gel electrophoresis ...
E, Karlsson, D L, Eaker, J, Porath
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Snake Venom Ophthalmia and Blindness Caused by the Spitting Cobra (Naja nigricollis) in Nigeria
American Journal of Tropical Medicine and Hygiene, 1976 Venom entered the eyes of 9 patients spat at by the spitting cobra, Naja nigricollis. In 5 the only effect was a simple conjunctivitis but 4 had corneal ulceration, 1 developed anterior uveitis indicating absorption of venom in the anterior chamber, and ...
Warrell, DA, Ormerod, LD
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Effects of Naja nigricollis venom on blood and tissue histamine
Toxicon, 1971Abstract Naja nigricollis venom produces a marked increase of blood histamine and release of tissue histamine. This latter effect is inhibited by EDTA and Egyptian polyvalent antivenin (containing no specific antivenin against Naja nigricollis venom).
A H, Mohamed +2 more
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Experimental studies on the spitting cobra ophthalmia (Naja nigricollis)
Graefe's Archive for Clinical and Experimental Ophthalmology, 1985Experimental studies were conducted to investigate the clinical and morphological effects of various doses of Naja nigricollis venom (0.1-5.0 mg) on the eyes of rabbits. Our findings suggest that in the early stage of the ophthalmia caused by the spitting cobra, specific fractions of the venom are responsible for the nitrogen mustardlike effect ...
J, Grüntzig +3 more
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[Comparison of two Elapidae venoms: Naja naja and Naja nigricollis].
Annales pharmaceutiques francaises, 1991In our study on the identification of snake venoms by electrofocusing technics, the protein profiles of Naja naja naja, Naja nigricollis pallida and Naja nigricollis West Africa were compared. The typical profile of venoms of Elapidae was easily identified in this comparison.
N, Pichon-Prum +2 more
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Purification and characterization of phospholipase a from the venom of Naja nigricollis
Toxicon, 1971Abstract Two enzymes with phospholipase A activity (AI and AII) have been purified from the venom of Naja nigricollis by gel filtration on Sephadex and ion-exchange chromatography on DEAE-cellulose. The yield of AII corresponded to about 3 per cent by weight of crude venom.
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1997
Abstract The cobra snakes of the species Naja (Elapidae) produce potent venoms with which they subdue their prey. Among the most toxic components are the curaremimetic toxins which provoke flaccid paralysis and death, as a result of respiratory failure. Detected by Boquet and coworkers (1966), Eaker and Porath showed, in 1967, that toxin
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Abstract The cobra snakes of the species Naja (Elapidae) produce potent venoms with which they subdue their prey. Among the most toxic components are the curaremimetic toxins which provoke flaccid paralysis and death, as a result of respiratory failure. Detected by Boquet and coworkers (1966), Eaker and Porath showed, in 1967, that toxin
openaire +1 more source