Results 41 to 50 of about 9,255 (180)

Bacterial Adaptation to Venom in Snakes and Arachnida

Microbiology Spectrum, 2022
Animal venoms are considered sterile sources of antimicrobial compounds with strong membrane-disrupting activity against multidrug-resistant bacteria. However, venomous bite wound infections are common in developing nations.
Elham Esmaeilishirazifard, Louise Usher, Carol Trim, Hubert Denise, Vartul Sangal, Gregory H. Tyson, Axel Barlow, Keith F. Redway, John D. Taylor, Myrto Kremyda-Vlachou, Sam Davies, Teresa D. Loftus, Mikaella M. G. Lock, Kstir Wright, Andrew Dalby, Lori A. S. Snyder, Wolfgang Wuster, Steve Trim, Sterghios A. Moschos   +18 more
doaj   +1 more source

Biochemical and kinetic properties of crude phospholipase A2 from Naja nigricollis venom [PDF]

, 2021
Snake envenomation has been a source of concern worldwide due to potential mortality risks associated with it. This study was carried out to investigate the biochemical and kinetic properties of crude phospholipase A2 (PLA2) from Naja nigricollis venom ...
Abubakar, Mujaheed, Sallau, Abdullahi Balarabe, Ibrahim, Zurki, Hussain, Abdulrazak Muhammad, Muhammad, Zaharaddeen, Garba, Laila Miftah   +5 more
core  

The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (Naja Species) Venoms

Frontiers in Immunology, 2021
African spitting cobras are unique among cobras for their potent anticoagulant venom activity arising from strong inhibition of Factor Xa. This anticoagulant effect is exerted by venom phospholipase A2 (Group I PLA2) toxins whose activity contributes to ...
Abhinandan Chowdhury, Abhinandan Chowdhury, Matthew R. Lewin, Matthew R. Lewin, Christina N. Zdenek, Rebecca Carter, Bryan G. Fry   +6 more
doaj   +1 more source

Antivenom activity of Moringa oleifera leave against pathophysiological alterations, somatic mutation and biological activities of Naja nigricollis venom

Scientific African, 2020
Moringa oleifera is a plant that has several medicinal properties, however, there are dearth of scientific information on the antivenom activities. This study therefore focused on the neutralizing activities of ethanol leaves extract of M.
Akindele Oluwatosin Adeyi, PhD, Siji Babafemi Ajisebiola, Esther Olubisi Adeyi, Chibuisi Gideon Alimba, Ph.D, Uchennaya Godwill Okorie   +4 more
doaj   +1 more source

Neuromuscular effects of nigexine, a basic phospholipase-a2 from naja-nigricollis venom

, 1991
Nigexine is a basic phospholipase A2 from the venom of the spitting cobra Naja nigricollis. In addition to its anticoagulant and cytolytic properties, nigexine also affects neuromuscular transmission in vitro. On chick biventer cervicis preparations, 1.5
Menez, A., Harvey, A.L., Rowan, E.G.
core   +4 more sources

Elapid snakes from the late Oligocene of Tanzania with comparison to extant Naja nigricollis.

, 2014
A, Elapid Morphotype A (RRBP 04320), posterior trunk vertebra. Note the lateral view is reversed; B, Elapid Morphotype B (RRBP 07257), posterior trunk vertebra; C, Naja nigricollis (USNM 320723), posterior trunk vertebra.
Jacob A. McCartney (539585), Patrick M. O’Connor (527812), Nancy J. Stevens (91642)   +2 more
core   +1 more source

Ecological relationships in two Afrotropical cobra species (Naja melanoleuca and Naja nigricollis)

, 2000
Aspects of comparative ecology were studied in the spitting cobra, Naja nigricollis, and the black forest cobra, Naja melanoleuca, from southeastern Nigeria. Both species were common and widely distributed in the study region. Naja melanoleuca inhabited
Francesco M Angelici, Luca Luiselli
core   +1 more source

In vivo neutralization of Naja nigricollis venom by Uvaria chamae [PDF]

, 2013
Uvaria chamae is a well known medicinal plant in Nigerian traditional medicine for the management of many diseases, but investigations concerning its pharmacological characteristics are rare.
Ebiloma, Godwin, Otini, Idoko Grace, Idoko, Grace Otini, Ebiloma, Godwin; id_orcid, Omale, James   +4 more
core   +1 more source

Discovery of Neuroprotective Venom‐Derived Candidates From Naja Mandalayensis in mHippoE‐18 Cells Via Fractionation and Proteomic Mapping

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Venom‐derived peptide diversity from Naja mandalayensis reveals bioactive subfractions capable of modulating neuronal oxidative stress responses. Integration of RP‐HPLC fractionation and proteomics identifies toxin families associated with improved mitochondrial function and cellular integrity in mHippoE‐18 cells, supporting venoms as a platform for ...
Brenda Rufino da Silva, Lais Campelo Mendes, Emidio Beraldo‐Neto, Carlos Alberto‐Silva   +3 more
wiley   +1 more source

Clinical effects of immunization, bleeding, and albumin-based fluid therapy in horses used as immunoglobulin source to produce a polyspecific antivenom (Echitab-plus-ICP) towards venoms of African snakes

Toxicon: X, 2023
During the production of snake antivenoms, the animals used as immunoglobulin source are subjected to processes that could deteriorate their physical condition. Therefore, these conditions must be carefully designed and validated.
Rose Mary Huertas, Mauricio Arguedas, Juan Manuel Estrada, Edwin Moscoso, Deibid Umaña, Gabriela Solano, Mariángela Vargas, Álvaro Segura, Andrés Sánchez, María Herrera, Mauren Villalta, Cynthia Arroyo-Portilla, José María Gutiérrez, Guillermo León   +13 more
doaj   +1 more source