Results 131 to 140 of about 13,887 (276)

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

Macromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou, John T. Leman, Harper Serringer, Ke Xia, Christopher N. LaFratta, Chaitanya Ullal, Edmund F. Palermo   +6 more
wiley   +1 more source

Polyvinylidene Fluoride: Reaction Engineering and Applications

Macromolecular Reaction Engineering, EarlyView.
An updated review on polyvinylidene fluoride (PVDF) is presented in this work. Its properties, important areas of application and different methods of production are described, with particular focus on emulsion polymerization, covering the latest advances in formulations and modeling studies.
Burak Hanamirian, Giuseppe Storti, Mattia Sponchioni   +2 more
wiley   +1 more source

Photochromic carbazole photoinitiators for precision visible‐light photopolymerization

Polymer International, EarlyView.
New carbazole–naphthopyran derivatives were employed as visible‐light‐activated photoinitiators, enabling rapid and localized radical photopolymerization to produce well‐defined thin solid objects within minutes. Abstract Two carbazole derivatives, each incorporating a naphthopyran unit and an aromatic ketone, were synthesized and evaluated as ...
Mauro Magalhães, Céu M Sousa, José R Fernandes, Paulo J Coelho   +3 more
wiley   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

Pest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus, Liina Soonvald, Iris Callewaert, Ana Isabel Silva, Ericmar Ávila Dos Santos, Silva Vilumets, Riina Kaasik, Sven Vereecken, Lenny Van Daele, Peter Dubruel, Jonathan Willow, Clauvis Nji Tizi Taning, Kristof De Schutter, Eve Veromann   +13 more
wiley   +1 more source

Chitosan‐protected dsRNA increases efficacy against Helicoverpa armigera without compromising biosafety for pollinators

Pest Management Science, EarlyView.
Chitosan/tripolyphosphate/double‐stranded RNA (dsRNA) nanoparticles enhance RNA interference efficacy of orally delivered dsRNA against Helicoverpa armigera. Nanoparticles reduce the LC50 and do not cause deleterious effects or toxicity on beneficial insects.
Daniel DN Vasquez, Lays A Teixeira, Rangel F Alves, Raire Cavalcante, Leonardo LP Macedo, Carmen SS Pires, Luciano P Silva, Maria CM Silva, Feras M Afifi, Carolina V Morgante, Martin G Edwards, Angharad MR Gatehouse, Maria F Grossi‐de‐Sa   +12 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source

Acid Resistant and Highly Silver Selective Membranes Based on Charged Nanoporous 2D‐Materials

Small, EarlyView.
In this work, new membranes based on charged & nanoporous nanosheets with unprecedented selectivity to silver versus a wide range of other metallic ions are reported. Furthermore, a demonstrated and lead specific intralamellar lead pathway is demonstrated. A potential applicability for ubiquitous silver in WEEE is validated.
Sarah M. Chevrier, Thibault Rosier, Bo Han, Lina Cherni, Fabien L. Olivier, Hélène Isnard, Jean‐Christophe P. Gabriel   +6 more
wiley   +1 more source

Toward Efficient and Reliable Chemical Upgrading Using Solid Oxide Electrochemical Reactors, Mechanisms, Challenges, and Design Principles

Small, EarlyView.
Solid oxide electrochemical reactors (SOERs) offer a compelling pathway for coupling renewable electricity with chemical manufacturing, but their real application is still limited by low efficiency and instability. This review systematically summarizes SOER reaction mechanisms, performance‐limiting factors, and recent progress toward high‐efficiency ...
Nai Shi, Yun Xie, Moses Oludayo Tadé, Zongping Shao   +3 more
wiley   +1 more source