Results 141 to 150 of about 13,887 (276)

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

open access: yesIntegrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li   +5 more
wiley   +1 more source

Investigating relationships among strontium, barium, and seasonality in wild baboons

open access: yesArchaeometry, EarlyView.
Abstract Geochemical profiles of Australopithecus africanus and baboon teeth show fluctuating trace elements, possibly reflecting seasonal diets. Here we use laser ablation–inductively coupled plasma–mass spectrometric measurements of calcium‐normalized strontium and barium ratios (Sr/Ca and Ba/Ca) and ion microprobe analyses of oxygen isotopes (δ18O ...
Maya Bharatiya   +12 more
wiley   +1 more source

Trace Element Patterns in Juvenile Wild Chimpanzee Dentitions

open access: yesArchaeometry, EarlyView.
ABSTRACT Trace elements are used to infer mammalian early‐life diets, environmental toxins, dispersal patterns, stress histories, and weaning ages. Here, we employ laser ablation‐inductively coupled plasma‐mass spectrometry (LA‐ICP‐MS) to reveal elemental patterns in our closest living relatives, chimpanzees.
Tanya M. Smith   +5 more
wiley   +1 more source

Droughts and human impact in the ancient Uaymil region of the Maya lowlands inferred from a 2800‐year sedimentary archive at Lake Kaná, Mexico

open access: yesBoreas, EarlyView.
The relationship between the climate and societal transformation in Maya lowlands has long been debated, particularly the role of drought in shaping the civilization trajectory during the Classic Period. A high‐resolution, multi‐proxy, geochemical record from Lake Kaná, located in the underexplored Uaymil region of the Yucatán Peninsula in Mexico ...
Haydar B. Martinez‐Dyrzo   +5 more
wiley   +1 more source

Orthotopic Esophageal Cancer Xenograft Model in Immunosuppressed Microminipigs for Near‐Infrared Fluorescence Endoscopy

open access: yesCancer Science, EarlyView.
We report the first successful orthotopic engraftment of human esophageal squamous cell carcinoma in immunosuppressed microminipigs and demonstrate high‐contrast near‐infrared fluorescence endoscopic detection using EGFR‐targeted cetuximab. This large‐animal model bridges preclinical imaging research and future clinical translation in esophageal cancer.
Takanori Miyake   +14 more
wiley   +1 more source

Effectiveness of Scenario‐Based Dental Hygiene Education Using Virtual Reality: Intraoral Radiography Training

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Purpose/Objectives This study aimed to develop a virtual reality simulation (VRS) program that is based on a scenario, training dental hygiene students in the intraoral bisecting angle technique. We tested the effectiveness of VRS in education using performance confidence (PC), clinical competency (CC) and learning satisfaction (LS).
Bogeun Lee   +6 more
wiley   +1 more source

Fracture load and three‐dimensional internal void analysis of direct composites used to restore worn molars

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This study evaluated (1) the load‐bearing capacity of molars restored with direct occlusal veneers fabricated either from short‐fiber‐reinforced composite (SFRC) or particulate‐filled composite (PFC) and the presence of internal voids within the materials, and (2) effect of water storage on the fracture load and correlation between internal ...
Topias Yli‐Urpo   +6 more
wiley   +1 more source

Proteostasis of organelles in aging and disease

open access: yesThe FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi   +5 more
wiley   +1 more source

Effects of Substructure Color and Restoration Thickness on the Final Color of Ultra‐Translucent Zirconia Ceramics

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective This in vitro study aimed to evaluate the effects of substructure color and restoration thickness on the final color of shade‐gradient ultra‐translucent zirconia ceramics. Material and Methods A total of 180 flat‐shaped ultra‐translucent zirconia specimens (5Y‐PSZ) with thicknesses of 0.4, 0.6, and 0.8 mm (n = 60) were fabricated and
Elif Yılmaz Biçer   +2 more
wiley   +1 more source

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