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Managed Care of Naked Mole-Rats
2021Naked mole-rats are a burgeoning model species in the field of biomedical research and are also housed at many zoos throughout the world. These mammals possess many traits that have a large impact on the way that they are kept in captivity such as their eusociality, thermolability and lack of need for drinking water.
Megan, Smith, Rochelle, Buffenstein
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Colony-specific dialects of naked mole-rats
Science, 2021Colony dialects are learned in early life but are modulated by the reigning ...
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Neural Computing and Applications, 2019
This work proposes a new swarm intelligent nature-inspired algorithm called naked mole-rat (NMR) algorithm. This NMR algorithm mimics the mating patterns of NMRs present in nature. Two types of NMRs called workers and breeders are found to depict these patterns.
Rohit Salgotra, Urvinder Singh
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This work proposes a new swarm intelligent nature-inspired algorithm called naked mole-rat (NMR) algorithm. This NMR algorithm mimics the mating patterns of NMRs present in nature. Two types of NMRs called workers and breeders are found to depict these patterns.
Rohit Salgotra, Urvinder Singh
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Lactate inhibits naked mole-rat cardiac mitochondrial respiration
Journal of Comparative Physiology B, 2022In aerobic conditions, the proton-motive force drives oxidative phosphorylation (OXPHOS) and the conversion of ADP to ATP. In hypoxic environments, OXPHOS is impaired, resulting in energy shortfalls and the accumulation of protons and lactate. This results in cellular acidification, which may impact the activity and/or integrity of mitochondrial ...
Kenny W. Huynh, Matthew E. Pamenter
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Animal Cognition, 1998
Naked mole-rats (Heterocephalus glaber, Rodentia: Bathyergidae) excavate extensive subterranean burrows with their procumbent incisors. Captive individuals often place a wood shaving or tuber husk behind their incisor teeth and in front of their lips and molar teeth while gnawing on substrates that yield fine particulate debris.
Gabriela Shuster, P. W. Sherman
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Naked mole-rats (Heterocephalus glaber, Rodentia: Bathyergidae) excavate extensive subterranean burrows with their procumbent incisors. Captive individuals often place a wood shaving or tuber husk behind their incisor teeth and in front of their lips and molar teeth while gnawing on substrates that yield fine particulate debris.
Gabriela Shuster, P. W. Sherman
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Spontaneous Disease and Pathology of Naked Mole-Rats
2021Naked mole-rats are highly valuable research models and popular exhibition animals at zoos worldwide. Here, we provide comprehensive descriptions of common postmortem findings of naked mole-rats from both research colonies and populations managed in zoological institutions.
Martha A, Delaney +2 more
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Sensory Systems of the African Naked Mole-Rat
2021Naked mole-rats share some sensory characteristics with other subterraneans, including lack of object vision, retention of the ability to entrain their circadian rhythm to light, and poor hearing. On the other hand, a characteristic that may be specialized in the naked mole-rat is their exquisite orienting responses to the touch of even a single body ...
Emily N, Vice +5 more
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Biochimie
Naked mole rats (NMRs) are renowned for their exceptional longevity and remarkable maintenance of health throughout their lifetime. Their subterranean lifestyle has led to adaptations that have resulted in elevated levels of a very high molecular weight hyaluronan in their tissues.
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Naked mole rats (NMRs) are renowned for their exceptional longevity and remarkable maintenance of health throughout their lifetime. Their subterranean lifestyle has led to adaptations that have resulted in elevated levels of a very high molecular weight hyaluronan in their tissues.
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Naked mole rats activate neuroprotective proteins during hypoxia
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, 2019AbstractNaked mole rats are a long‐lived animal model that age much like humans, but that can also withstand oxidative damage, cancer, neurodegenerative diseases, and severe hypoxic conditions, which is of particular interest to this study. The conditions of their underground burrows result in competition for oxygen consumption, yet despite this oxygen
Liam J. Hawkins +4 more
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Extreme hypoxia tolerance of naked mole-rat brain
NeuroReport, 2009Mammalian brains have extremely high levels of aerobic metabolism and typically suffer irreversible damage after brief periods of oxygen deprivation such as occur during stroke or cardiac arrest. Here we report that brain tissue from naked mole-rats, rodents that live in a chronically low-oxygen environment, is remarkably resistant to hypoxia: naked ...
John, Larson, Thomas J, Park
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