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Evaluation of Nalbuphine Hydrochloride

American Journal of Health-System Pharmacy, 1980
The chemical properties, animal and human pharmacology, analgesic efficacy, relative potency, administration, and adverse effects of nalbuphine, a recently marketed, parenteral, strong analgesic with narcotic antagonist properties, are reviewed. Acute, subacute, and chronic toxicity studies in animals revealed no unusual adverse effects.
Miller Russell R, Russell R Miller
exaly   +3 more sources

Nalbuphine analgesia in the prehospital setting

American Journal of Emergency Medicine, 1988
Forty-six patients with moderate to severe pain caused by orthopedic injuries, burns, multiple trauma, or intraabdominal conditions were treated with intravenous (IV) nalbuphine hydrochloride (Nubain; DuPont Pharmaceuticals, Wilmington, DE) by paramedics before arrival at the hospital. Patients who weighed less than 60 kg received 15 mg nalbuphine, and
R A Myers
exaly   +3 more sources

Epidural Lidocaine, Nalbuphine, and Lidocaine–Nalbuphine Combination in Donkeys

Journal of Equine Veterinary Science, 2016
Abstract Nalbuphine is a lipophilic semisynthetic κ-agonist/μ-antagonist opioid that has been used for epidural anesthesia in humans and dogs but not in donkeys. The purpose of the present study was to report the effect of epidural nalbuphine either alone or in combination with lidocaine compared with lidocaine alone.
Faisal A. Torad, Elham A. Hassan
openaire   +1 more source

Acute Intravenous Premedication with Nalbuphine

Anesthesia & Analgesia, 1977
In a randomized, double blind study of 75 adult surgical patients, nalbuphine (0.1 mg/kg), morphine (0.1 mg/kg), or a placebo were administered intravenously as premedication 12 to 16 minutes prior to induction of anesthesia. Comparison of the 3 groups showed: (1) patients receiving nalbuphine and morphine had a significant reduction of minute ...
R J, Fragen, N, Caldwell
openaire   +2 more sources

Butorphanol and nalbuphine: A pharmacologic comparison

Oral Surgery, Oral Medicine, Oral Pathology, 1985
The agonist/antagonist analgesics, butorphanol (Stadol) and nalbuphine (Nubain), are being increasingly employed as intravenous sedation agents; nalbuphine will be available in the future as an oral analgesic. The drugs possess numerous pharmacologic similarities and some dissimilarities.
T J, Pallasch, C J, Gill
openaire   +2 more sources

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