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Evaluation of nalbuphine for abuse potential
Clinical Pharmacology & Therapeutics, 1972Nalbuphine is a narcotic antagonist and analgesic. A dose of 8 mg. per 70 Kg. of nalbuphine in man produces subjective effects which resemble those of 10 mg. per 70 Kg. of morphine. Nalbuphine, in doses of 24 and 72 mg. per 70 Kg., produces mild effects which more closely resemble those of nalorphine.
D R, Jasinski, P A, Mansky
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Nalbuphine-induced Pulmonary Edema
Chest, 1986We report the occurrence of acute pulmonary edema in a patient receiving therapy with nalbuphine, a synthetic narcotic analgesic. Other potential causes of acute pulmonary edema were excluded. It is likely that all opiate drugs share the propensity to produce acute pulmonary edema, and nalbuphine resembles other opiates in this regard.
A, Stadnyk, R F, Grossman
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Effects of nalbuphine on the cardioprotective effect of morphine in rats
International Journal of Cardiology, 2021Yao Lu
exaly