Antimalarial Potency of Tinospora crispa Stem Extract and Artesunate Against Plasmodium berghei: A Study on Combination Therapy [PDF]
Journal of Tropical MedicineMalaria continues to be a significant global health burden, with over 249 million cases and 619,000 deaths reported in 2022, primarily affecting tropical and subtropical regions.
Sakaewan Ounjaijean, Voravuth Somsak
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Resolving coral temperature vulnerability through heat and cold bleaching thresholds [PDF]
Communications BiologyCoral bleaching is most commonly associated with heat stress, while cold-water bleaching remains an underrecognized threat. Building upon the widely used ED50 metric for standardized heat tolerance, we introduce a new metric, cold ED50, to quantify cold ...
Yusuf C. El-Khaled +9 more
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Behavioral pharmacology of novel synthetic indazole, indole, and benzimidazole cannabinoids in rodents [PDF]
Journal of Cannabis ResearchBackground Synthetic cannabinoids (SC) are created as alternatives to delta-9-tetrahydrocannabinol (∆9-THC) and can cause serious side effects like hallucinations and death.
Ritu A. Shetty +5 more
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Drug and Alcohol Dependence Reports, 2023 Aims: Benzofurans are used recreationally, due their ability to cause psychostimulant and/or entactogenic effects, but unfortunately produce substantial adverse effects, including death. Three benzofurans 5-(2-aminopropyl)-2,3-dihydrobenzofuran (5-APDB),
Rebecca D. Hill +4 more
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Macedonian Veterinary Review, 2021 The objective of our research was to estimate the therapeutic index and assess the interaction of alfaxalone (IP) with ketamine or xylazine (IM) in chicks by using isobolographic analysis.
Amjed Najem Alatrushi, Ahmed Salah Naser
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Veterinary Medicine International, 2022 Malaria is still a significant health problem in endemic countries and increases Plasmodium resistance to the available antimalarial drugs. Hence, this study aimed to investigate the antimalarial activity of allicin and its combination with artesunate ...
Sakaewan Ounjaijean, Voravuth Somsak
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Synergistic anti-allodynic effect between intraperitoneal thalidomide and morphine on rat spinal nerve ligation-induced neuropathic pain [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundThalidomide has been recognized as having an anti-allodynic effect against neuropathic pain induced by spinal nerve ligation. Its clinical beneficial effects are mainly derived from its immune-modulating property, which is known to influence ...
Hyung Gon Lee +4 more
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Fungicide resistance among Cladobotryum spp. – causal agents of cobweb disease of the edible mushroom Agaricus bisporus [PDF]
, 2000 A survey of fungicide resistance among isolates of the mushroom pathogens Cladobotryum mycophilum and C. dendroides Types I and II was undertaken, with respect to the active ingredients thiabendazole, carbendazim (benzimidazoles) and prochloraz manganese
Bonnen +19 more
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Lead optimisation of dehydroemetine for repositioned use in malaria [PDF]
, 2020 Drug repositioning offers an effective alternative to de novo drug design to tackle the urgent need for novel anti-malarial treatments. The anti-amoebic compound, emetine dihydrochloride, has been identified as a potent in-vitro inhibitor of the multi ...
Abubaker, M +8 more
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Sensitivity towards DMI fungicides and haplotypic diversity of their CYP51 target in the Mycosphaerella graminicola population of Flanders [PDF]
, 2014 Septoria leaf blotch, caused by the fungus Mycosphaerella graminicola, is the most important wheat disease in Northwestern Europe, and is currently controlled by fungicide applications.
Curvers, Katrien +4 more
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