Results 1 to 10 of about 1,236 (154)

Comparison of ED95 of Butorphanol and Sufentanil for gastrointestinal endoscopy sedation: a randomized controlled trial [PDF]

BMC Anesthesiology, 2020
Background Butorphanol, a synthetic opioid partial agonist analgesic, has been widely used to control perioperative pain. However, the ideal dose and availability of butorphanol for gastrointestinal (GI) endoscopy are not well known.
Linmin Pan, Limei Chen
exaly   +6 more sources

Comparison of Intubating Conditions at 60 Seconds with Cisatracurium 4*ED95 Dose and Cisatracurium 2*ED95 Dose Plus Priming Dose and Low Dose Ketamine

Journal of Pharmacy and Bioallied Sciences, 2023
Introduction: To compare the intubating conditions at 60 seconds between 4*ED95 dose of cisatracurium and 2*ED95 dose of cisatracurium in combination with priming and low dose ketamine Primary Objective: jaw relaxation for laryngoscopy, vocal cord ...
Rahul G Daga, Irbinder Kour Bali, Pushparaj Nilkanth Patil, Rohit Ghanshyamdas Daga, Rashmi Daga, G S Devika   +5 more
exaly   +5 more sources

ED95 of remimazolam in nasal administration for attenuating preoperative anxiety in children

Frontiers in Medicine, 2023
BackgroundPreoperative anxiety often prevails in children at higher levels than adults, which is a common impediment for surgeons and anesthesiologists. It is of great necessity to explore an appropriate medication to improve this situation. Remimazolam,
Yuan Gong, Gong Yuan
exaly   +5 more sources

ED50 and ED95 of intrathecal levobupivacaine with opioids for Caesarean delivery [PDF]

British Journal of Anaesthesia, 2011
Abstract Background This prospective randomized double-blind dose–response study aimed to determine the ED 50 and ED 95 of intrathecal levobupivacaine combined with morphine and sufentanil for elective Caesarean delivery. Methods Parturients undergoing elective Caesarean delivery were included and allocated to five levobupivacaine dose groups (6,
Lionel Bouvet, Emmanuel Boselli, B Allaouchiche   +2 more
exaly   +3 more sources

Determination of the ED95 of a single bolus dose of dexmedetomidine for adequate sedation in obese or nonobese children and adolescents [PDF]

British Journal of Anaesthesia, 2021
With the increasing prevalence of children who are overweight and with obesity, anaesthesiologists must determine the optimal dosing of medications given the altered pharmacokinetics and pharmacodynamics in this population. We therefore determined the single dose of dexmedetomidine that provided sufficient sedation in 95% (ED95) of children with and ...
Bin Wu, Quanhong Zhou
exaly   +3 more sources

The dose-dependent anesthetic effect of ciprofol on 8-week-old C57BL/6J mice [PDF]

Frontiers in Pharmacology
ObjectiveThe research is to explore the half effective dose (ED50) and 95% effective dose (ED95) of ciprofol with intraperitoneal injection of 8-week-old C57BL/6J adult mice, which will provide experimental basis for the reasonable dose design of ...
Huan Wang, Yongliang Chi, Zhaobing Han, Xiwen Geng, Guimao Cao   +4 more
doaj   +2 more sources

Determination of optimal combined doses of oral midazolam and intranasal dexmedetomidine for use in pediatric magnetic resonance imaging [PDF]

World Journal of Pediatric Surgery
Background Sedation is often required for infant and preschool children to obtain clear magnetic resonance imaging (MRI). This study was designed to determine the 95% effective dose (ED95) of oral midazolam (MID) and intranasal dexmedetomidine (DEX) in ...
Yaoqin Hu, Jing Gao, Jialian Zhao, Jian Tang, Chunying Bao, Haiya Tu   +5 more
doaj   +2 more sources

Age-Stratified ED₉ ₅ of Remimazolam Tosilate for Moderate Sedation in Pediatric Patients: A Biased Coin Design Study. [PDF]

Drug Des Devel Ther
Bingqing Zhu,* Wenjun Meng,* Kunyun Pan,* Li Peng, Xu Chen, Sheng Wang, Chengwei Yang Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China*These authors contributed equally to ...
Zhu B, Meng W, Pan K, Peng L, Chen X, Wang S, Yang C.   +6 more
europepmc   +3 more sources

Determination of the ED95 of intrathecal hyperbaric prilocaine with sufentanil for scheduled cesarean delivery: a dose-finding study based on the continual reassessment method [PDF]

BMC Anesthesiology, 2020
Background Scheduled cesarean section is routinely performed under spinal anesthesia using hyperbaric bupivacaine. The current study was undertaken to determine the clinically relevant 95% effective dose of intrathecal 2% hyperbaric prilocaine co ...
P. Goffard, Y. Vercruysse, R. Leloup, J-F Fils, S. Chevret, Y. Kapessidou   +5 more
doaj   +4 more sources

Chloroprocaine ED₅₀ and ED₉₅ for Propofol Injection Pain Prevention: Dixon's Sequential Method. [PDF]

J Pain Res
This study aimed to estimate the median effective dose (ED50) and the 95% effective dose (ED95) of intravenous chloroprocaine (CP), administered pre-emptively for the prevention of propofol-induced injection pain, using Dixon's up-and-down sequential allocation method, and to characterize the associated dose-response relationship.First, apply a ...
Lai P, Yang X, Yang X, Xuan Q, Fang Y, He Z, Chen B, Yin G.   +7 more
europepmc   +5 more sources