Results 11 to 20 of about 1,434 (182)
Determination of optimal combined doses of oral midazolam and intranasal dexmedetomidine for use in pediatric magnetic resonance imaging [PDF]
World Journal of Pediatric SurgeryBackground Sedation is often required for infant and preschool children to obtain clear magnetic resonance imaging (MRI). This study was designed to determine the 95% effective dose (ED95) of oral midazolam (MID) and intranasal dexmedetomidine (DEX) in ...
Yaoqin Hu +5 more
core +3 more sources
Swiss Medical Weekly, 2011 OBJECTIVE: Various research programmes have shown that intraoperative infusion of remifentanil has been associated with postoperative hyperalgesia. Previous studies have demonstrated that low-dose ketamine can inhibit central sensitisation and prevent opioid-induced hyperalgesia (OIH). However, the optimal ketamine dose to prevent OIH has not been
L Hang, D Shao, W Sun
core +5 more sources
Determination of the 95% effective dose of remimazolam to achieve loss of consciousness during anesthesia induction in different age groups [PDF]
Korean Journal of Anesthesiology, 2022 BACKGROUND: Remimazolam is a new ultra short-acting benzodiazepine originally developed as an improved version of midazolam. Recent studies have demonstrated non-inferiority of remimazolam to propofol in general anesthesia.
Lee, SY +6 more
core +3 more sources
Ibrain, 2023 This study aimed to determine the values of the half‐effective dose (ED50) and 95% effective dose (ED95) of remimazolam besylate used in the procedural sedation of endoscopic retrograde cholangiopancreatography (ERCP).
Li‐Jin Zhao +10 more
core +2 more sources
Determination of the 95% effective dose of remimazolam tosylate in anesthesia induction inhibits endotracheal intubation response in senile patients [PDF]
Frontiers in Pharmacology, 2023 Background and Purpose: The prevalence of elderly patients prompts anesthesiologists to determine the optimal dose of medication due to the altered pharmacokinetics and pharmacodynamics of this population.
Ru Ouyang +7 more
core +3 more sources
The dose-dependent anesthetic effect of ciprofol on 8-week-old C57BL/6J mice [PDF]
Frontiers in PharmacologyObjectiveThe research is to explore the half effective dose (ED50) and 95% effective dose (ED95) of ciprofol with intraperitoneal injection of 8-week-old C57BL/6J adult mice, which will provide experimental basis for the reasonable dose design of ...
Huan Wang +4 more
doaj +2 more sources
Synephrine potentiates lidocaine‐induced cutaneous analgesia via α‐adrenergic receptors in male rats [PDF]
Physiological Reports, Volume 14, Issue 6, March 2026.The enhanced analgesic effects of lidocaine–synephrine or lidocaine–phenylephrine combinations are mediated via α‐adrenergic receptor activation. Abstract This study aimed to assess the cutaneous analgesic effect of the lidocaine–synephrine combination and its underlying α‐adrenergic receptor‐mediated mechanism in comparison with phenylephrine ...
An‐Kuo Chou +5 more
wiley +2 more sources
Revista Brasileira de Anestesiologia, 2009 JUSTIFICATIVA E OBJETIVOS: Os efeitos do IMC na dispersão subaracnóidea de bupivacaína são controversos. O presente estudo avaliou a ED95 de bupivacaína subaracnóidea em cesarianas eletivas em mulheres obesas e naquelas com peso normal.
Yung Lee +7 more
core +2 more sources
Energies, 2011 Ethanol is conventionally used as a blend with gasoline due to its similar properties, especially the octane number. However, ethanol has also been explored and used as a diesel substitute. While a low-blend of ethanol with diesel is possible with use of
Atsushi Fukuda +3 more
core +2 more sources
Clinical and Experimental Obstetrics & Gynecology, 2021 Objective: This study aimed to determine the ED50 and ED95 of 10 mg of 0.5% ropivacaine combined with different doses of sufentanil in lumbar anesthesia for cesarean sections in patients with severe preeclampsia by the sequential method. Methods: A total
Long-Xin Zhang +3 more
core +2 more sources