ED95 of remimazolam in nasal administration for attenuating preoperative anxiety in children
Frontiers in Medicine, 2023 BackgroundPreoperative anxiety often prevails in children at higher levels than adults, which is a common impediment for surgeons and anesthesiologists. It is of great necessity to explore an appropriate medication to improve this situation. Remimazolam,
Xiang Long +6 more
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Swiss Medical Weekly, 2011 OBJECTIVE: Various research programmes have shown that intraoperative infusion of remifentanil has been associated with postoperative hyperalgesia.
L Hang, D Shao, W Sun
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BMC Anesthesiology, 2023 Background This study aims to estimate the safety, efficacy, and median effective dose (ED50) of esketamine for preventing early postoperative pain in patients undergoing laparoscopic cholecystectomy.
Zhongling Xu +5 more
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The effective dose of remimazolam in combination with sufentanil for sedation during transvaginal oocyte retrieval: an up-and-down sequential allocation trial [PDF]
BMC AnesthesiologyBackground The potential adverse effects of propofol on fertilization outcomes have raised concerns among patients undergoing anesthesia for oocyte retrieval. Remimazolam is a new type of ultra-short-acting benzodiazepine.
Yanfei Lu +5 more
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Determination of the Median Effective Dose of Ciprofol Combined with Sufentanil in Inhibiting Tracheal Intubation Response in Female Patients [PDF]
Scientific ReportsTo determine the median effective dose (ED50) and the 95% effective dose (ED95) of ciprofol combined with sufentanil for inhibiting the tracheal intubation response in female patients and to evaluate the hemodynamic stability and adverse events ...
Li Zhao +8 more
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Effective Dosage of Ciprofol for the Induction of General Anesthesia Across Diverse Age Groups in Adults: A Single-Center, Prospective, Non-Randomized Sequential Trial [PDF]
Journal of Pain ResearchLizhen Deng,* Chunyuan Zhang,* Meiyun Tan, Wei Zeng, Guozhan Luo, Ping Li Department of Anesthesiology, Affiliated Boai Hospital of Zhongshan, Zhongshan, Guangdong, People’s Republic of China*These authors contributed equally to ...
Deng L +5 more
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Determination of the median effective dose of sufentanil combined with remimazolam in inhibiting tracheal intubation response [PDF]
Scientific ReportsTo determine the median effective dose (ED50) and 95% effective dose (ED95) of sufentanil combined with remimazolam for inhibiting the tracheal intubation response in patients undergoing general anesthesia and to evaluate the hemodynamic stability and ...
Lin Feng +8 more
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ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery [PDF]
Frontiers in MedicineObjectiveThe spinal block was limited to the operative side during unilateral spinal anesthesia, which has less physiological interference and fewer complications for the patient.
Chao Lin +6 more
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Synephrine potentiates lidocaine-induced cutaneous analgesia via α-adrenergic receptors in male rats. [PDF]
Physiol RepThe enhanced analgesic effects of lidocaine–synephrine or lidocaine–phenylephrine combinations are mediated via α‐adrenergic receptor activation. Abstract This study aimed to assess the cutaneous analgesic effect of the lidocaine–synephrine combination and its underlying α‐adrenergic receptor‐mediated mechanism in comparison with phenylephrine ...
Chou AK +5 more
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Effective Dose of Oliceridine Fumarate Co-Administered with Remimazolam in Suppressing Gastroscope Insertion Responses for Adults [PDF]
Drug Design, Development and TherapyWeilin Yang,1,* Rui Zhou,2,* Xinyu Zhou,1 Xuemeng Chen,1 Dan Zhou,1 Xianjie Zhang1 1Department of Anesthesiology, Deyang People’s Hospital, Deyang, 618000, People’s Republic of China; 2Shanghai Key Laboratory of Anesthesiology and Brain ...
Yang W +5 more
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