The effective sedative dose of remimazolam for BIS <60 during general anesthesia induction between elderly and non-elderly patients-A randomized controlled trial [PDF]
BackgroundThere is lack research about the effect of sufentanil on the effective dose of remimazolam during general anesthesia in both elderly and non-elderly patients scheduled for day surgery. This study was conducted to estimate the 95% effective dose
Jun-Li Zheng +10 more
doaj +2 more sources
Determination of ED50 and ED95 for Ciprofol in Morbidly Obese Patients During Induction of General Anesthesia: A Single-Center, Up-and-Down Study Based on Lean Body Weight [PDF]
Chao-min Wu, Ji-min Wu, Jian-xin Jiang, Qiao min Xu, Xue-hao Han, Gong-chen Duan Department of Anesthesiology, Lishui People’s Hospital, The First Affiliated Hospital of Lishui University, Wenzhou Medical University Lishui Hospital, Lishui, People’s ...
Wu CM +5 more
doaj +2 more sources
Optimal volume of local anaesthetic for adductor canal block: using the continual reassessment method to estimate ED95 [PDF]
Theoretically, the ideal volume of local anaesthetic for adductor canal block (ACB) would ensure sufficient filling of the canal and avoid proximal spread to the femoral triangle. In this dose-finding study, we aimed to investigate the minimal effective volume for an ACB needed to fill the adductor canal distally in at least 95% of patients (ED95).We ...
Jæger, P. +6 more
exaly +4 more sources
OBJECTIVE: Various research programmes have shown that intraoperative infusion of remifentanil has been associated with postoperative hyperalgesia.
L Hang, D Shao, W Sun
doaj +3 more sources
Jiabei Li,1,2 Wuchang Fu,3 Na Wang,1 Sisi Zeng,1 Xuechao Li,1 Jixiang Wan,1 Fangjun Wang1 1Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, People’s Republic of China; 2Department of Anesthesiology, Meishan ...
Xuechao Li
exaly +2 more sources
Liangliang Gao,1,* Aiping Tan,1,* Zehui Wang,2 Lei Wei,1 Xingshuang Wang1 1Department of Anesthesiology, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, People’s Republic of China; 2Department of Anesthesiology, Cixi ...
Gao L, Tan A, Wang Z, Wei L, Wang X
doaj +2 more sources
ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery [PDF]
ObjectiveThe spinal block was limited to the operative side during unilateral spinal anesthesia, which has less physiological interference and fewer complications for the patient.
Chao Lin +6 more
doaj +2 more sources
Determination of the median effective dose of sufentanil combined with remimazolam in inhibiting tracheal intubation response [PDF]
To determine the median effective dose (ED50) and 95% effective dose (ED95) of sufentanil combined with remimazolam for inhibiting the tracheal intubation response in patients undergoing general anesthesia and to evaluate the hemodynamic stability and ...
Lin Feng +8 more
doaj +2 more sources
Determination of the 95% effective dose of remimazolam to achieve loss of consciousness during anesthesia induction in different age groups [PDF]
Background Remimazolam is a new ultra short-acting benzodiazepine originally developed as an improved version of midazolam. Recent studies have demonstrated non-inferiority of remimazolam to propofol in general anesthesia.
Juyeon Oh +6 more
doaj +1 more source
Synephrine potentiates lidocaine-induced cutaneous analgesia via α-adrenergic receptors in male rats. [PDF]
The enhanced analgesic effects of lidocaine–synephrine or lidocaine–phenylephrine combinations are mediated via α‐adrenergic receptor activation. Abstract This study aimed to assess the cutaneous analgesic effect of the lidocaine–synephrine combination and its underlying α‐adrenergic receptor‐mediated mechanism in comparison with phenylephrine ...
Chou AK +5 more
europepmc +2 more sources

