Results 41 to 50 of about 1,434 (182)

A Monte Carlo simulation study comparing the up and down, biased-coin up and down and continual reassessment methods used to estimate an effective dose (ED95 or ED90) in anaesthesiology research

, 2023
Background: Dose-finding studies in anaesthesiology aim to target the effective dose (ED) of an anaesthetic agent in a specific population. The common dose-finding designs used are the up and down method (UDM), the biased-coin up and down (BCD), and the ...
Kapessidou, Panayota, Guntz, Emmanuel, Van Der Linden, Philippe, Fils, Jean François   +3 more
core   +1 more source

Intravenous Bolus of Dexmedetomidine for Treatment of Severe Shivering After Caesarean Delivery Under Combined Spinal-Epidural Anaesthesia: A Randomized Dose-Response Study

Drug Design, Development and Therapy
Meijuan Yang,1,* ShuXi Li,1,* Dan Drzymalski,2 Xinzhong Chen1 1Department of Anaesthesia, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2Department of Anaesthesiology and Perioperative Medicine ...
Li S, Drzymalski D, Yang M, Chen X
core   +2 more sources

Effective Doses of Nalbuphine Combined with Propofol in Painless Hysteroscopy

International Journal of General Medicine, 2022
Weiwei Zhong,* Chen Chen,* Weixiang Tang Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China*These authors contributed equally to this workCorrespondence ...
Zhong W, Chen C, Tang W
doaj  

Determination of the Dose-Response Relationship of Epidural Dexmedetomidine Combined with Ropivacaine for Labor Analgesia

Drug Design, Development and Therapy, 2022
Jian-Xin Ni,1 Jia-Li Feng,2 Sheng-Jie Yao,1 Li-Feng Ni,1 Shao-Bo Song,1 Cong-Zhong Song,1 Xiao-Wei Qian,3 Zhong Mei,1,3,* Jing Yu1,* 1Department of Anesthesiology, Affiliated Xiaoshan Hospital, Hangzhou Normal University (Zhejiang Xiaoshan ...
Ni JX, Feng JL, Yao SJ, Ni LF, Song SB, Song CZ, Qian XW, Mei Z, Yu J   +8 more
doaj  

Pharmacodynamic analysis of intravenous bolus remimazolam for loss of consciousness in patients undergoing general anaesthesia: a randomised, prospective, double-blind study

, 2022
Background: Remimazolam is a new rapid offset benzodiazepine used for procedural sedation and general anaesthesia. This study evaluated the efficacy and safety of i.v. bolus remimazolam during induction of anaesthesia.
김현창, 한동우, 송영, 채동우
core   +1 more source

Dose–response study of prophylactic nitroglycerin for prevention of pituitrin-induced hypertension during laparoscopic myomectomy: a prospective, randomized study

Frontiers in Medicine, 2023
ObjectiveTo determine the dose–response of nitroglycerin in preventing pituitrin-induced hypertension in patients undergoing laparoscopic myomectomy.MethodsHundred patients scheduled for elective laparoscopic myomectomy were randomly allocated into one ...
Jin Wang, Jin Wang, Qiang Xu, Qiang Xu, Fei Xiao, Gang Chen   +5 more
doaj   +1 more source

Optimal volume of local anaesthetic for the adductor canal block:Using the continual reassessment method to estimate the ED95

, 2015
Background: Theoretically, the ideal volume of local anaesthetic for adductor canal block (ACB) would ensure sufficient filling ofthe canal and avoid proximal spread to the femoral triangle.
Siersma, Volkert Dirk, Brøndum, V., Jæger, P., Dahl, J. B., Jenstrup, M. T., Lund, J., Hilsted, K. L.   +6 more
core   +1 more source

Rethinking Statin Dosage in Coronary Disease

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
It is widely acknowledged that a sufficient statin dose is important in the management of symptomatic coronary disease, along with weight reduction and appropriate antithrombotic, blood pressure, and diabetes pharmacotherapy. Mid‐range statin doses have been shown to achieve the maximum improvements in total mortality and have the advantage of greater ...
Simon B. Dimmitt, Hans G. Stampfer, Michael C. Kennedy, Jennifer H. Martin   +3 more
wiley   +1 more source

Ultrasound-Guided Rectus Sheath Block Combined with Butorphanol for Single-Incision Laparoscopic Cholecystectomy: What is the Optimal Dose of Ropivacaine?

Journal of Pain Research, 2020
Huimin Fu, Yu Fu, Xingguo Xu, Yongtao Gao Department of Anesthesiology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People’s Republic of ChinaCorrespondence: Xingguo Xu; Yongtao GaoDepartment of Anesthesiology, Affiliated Hospital ...
Fu H, Fu Y, xu X, Gao Y
doaj  

Comparison of Corticosteroid Regimens for COVID-19 and Non-COVID-19 ARDSTake-Home Points

CHEST Critical Care
Background: Although previous trials suggest that systemic corticosteroids improve survival in ARDS, the optimal dose remains uncertain. Research Question: Which corticosteroid dose offers the greatest efficacy, safety, or both in ARDS?
Ryosuke Imai, MD, Takayuki Niitsu, MD, Monica Yun Liu, MD, PhD, Hilary Faust, MD, Lynn M. Schnapp, MD, Shota Yamamoto, MD, PhD   +5 more
doaj   +1 more source