Results 41 to 50 of about 2,289 (201)

Chloroprocaine ED₅₀ and ED₉₅ for Propofol Injection Pain Prevention: Dixon's Sequential Method. [PDF]

J Pain Res
This study aimed to estimate the median effective dose (ED50) and the 95% effective dose (ED95) of intravenous chloroprocaine (CP), administered pre-emptively for the prevention of propofol-induced injection pain, using Dixon's up-and-down sequential allocation method, and to characterize the associated dose-response relationship.First, apply a ...
Lai P, Yang X, Yang X, Xuan Q, Fang Y, He Z, Chen B, Yin G.   +7 more
europepmc   +4 more sources

Design Issues for Generalized Linear Models: A Review

, 2006
Generalized linear models (GLMs) have been used quite effectively in the modeling of a mean response under nonstandard conditions, where discrete as well as continuous data distributions can be accommodated.
Ghosh, Malay, Khuri, André I., Mukherjee, Bhramar, Sinha, Bikas K.   +3 more
core   +3 more sources

Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes. [PDF]

, 2005
The vacuolating cytotoxin VacA is a major virulence factor of Helicobacter pylori, a bacterium responsible for gastroduodenal ulcers and cancer. VacA associates with lipid rafts, is endocytosed, and reaches the late endocytic compartment where it induces
Nils Gauthier, Pascale Monzo, Vincent Kaddai, Anne Doye, Vitorio Ricci, Patrice Boquet, Hal Id Inserm   +6 more
core   +2 more sources

Machine Learning Model for an App‐Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis

Veterinary Dermatology, Volume 37, Issue 2, Page 236-246, April 2026.
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Xavier Langon, Mathieu Montoya, Isabelle Gourdon   +2 more
wiley   +1 more source

Does Climate Change Alter Weed Management Recommendations? Evaluating the Impact of Elevated CO2 on Plant Growth and the Critical Period of Weed Control

Weed Research, Volume 66, Issue 2, March/April 2026.
ABSTRACT Climate change challenges crop production, driving rising temperatures and extreme weather events. Additionally, increased atmospheric CO2 alters competitive dynamics between crops and weeds. While previous research has examined individual plant responses to elevated CO2, its direct impact on weed management recommendations remains ...
Emma G. Kubinski, Kevin E. Sheridan, Fabian D. Menalled   +2 more
wiley   +1 more source

Ultrasound-Guided Rectus Sheath Block Combined with Butorphanol for Single-Incision Laparoscopic Cholecystectomy: What is the Optimal Dose of Ropivacaine?

Journal of Pain Research, 2020
Huimin Fu, Yu Fu, Xingguo Xu, Yongtao Gao Department of Anesthesiology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People’s Republic of ChinaCorrespondence: Xingguo Xu; Yongtao GaoDepartment of Anesthesiology, Affiliated Hospital ...
Fu H, Fu Y, xu X, Gao Y
doaj  

Ilioinguinal and iliohypogastric nerves cannot be selectively blocked by using ultrasound guidance: a volunteer study [PDF]

, 2017
Background Ilioinguinal (IL) and iliohypogastric (IH) nerve blocks are used in patients with chronic postherniorrhaphy pain. The present study tested the hypothesis that our method, previously developed in cadavers, blocks the nerves separately and ...
Colvin, L., Colvin, L., Curatolo, M., Eichenberger, U., Luyet, C., Schmutz, M., Schumacher, P. M.   +6 more
core  

Beeinflussung der Mivacurium-induzierten Muskelrelaxation durch S(+)-Ketamin [PDF]

, 2019
Die Allgemeinanästhesie setzt sich aus einem Medikamentencocktail zusammen, das aus einem Hypnotikum, einem Muskelrelaxans sowie einem Analgetikum besteht. Die Analgetika sind der Opioidgruppe zugeordnet (z. B. Fentanyl oder Sufentanil).
Hescher-Jost, Ilona
core   +1 more source

Rethinking Statin Dosage in Coronary Disease

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
It is widely acknowledged that a sufficient statin dose is important in the management of symptomatic coronary disease, along with weight reduction and appropriate antithrombotic, blood pressure, and diabetes pharmacotherapy. Mid‐range statin doses have been shown to achieve the maximum improvements in total mortality and have the advantage of greater ...
Simon B. Dimmitt, Hans G. Stampfer, Michael C. Kennedy, Jennifer H. Martin   +3 more
wiley   +1 more source

Comparison of Corticosteroid Regimens for COVID-19 and Non-COVID-19 ARDSTake-Home Points

CHEST Critical Care
Background: Although previous trials suggest that systemic corticosteroids improve survival in ARDS, the optimal dose remains uncertain. Research Question: Which corticosteroid dose offers the greatest efficacy, safety, or both in ARDS?
Ryosuke Imai, MD, Takayuki Niitsu, MD, Monica Yun Liu, MD, PhD, Hilary Faust, MD, Lynn M. Schnapp, MD, Shota Yamamoto, MD, PhD   +5 more
doaj   +1 more source